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The map label for this gene is dppA [H]

Identifier: 16272793

GI number: 16272793

Start: 899639

End: 901288

Strand: Direct

Name: dppA [H]

Synonym: HI0853

Alternate gene names: 16272793

Gene position: 899639-901288 (Clockwise)

Preceding gene: 16272792

Following gene: 16272794

Centisome position: 49.16

GC content: 37.7

Gene sequence:

>1650_bases
ATGCTTATGAAACTAAAAGCAACATTAACTCTCGCCGCTGCAACTCTTGTTTTGGCAGCTTGTGATCAATCTAGCTCGGC
AAATAAATCTACCGCTCAAACTGAAGCAAAATCCTCGTCAAATAATACTTTCGTTTATTGCACAGCGAAAGCTCCATTGG
GATTTAGCCCTGCGTTAATAATTGAAGGTACTTCTTATAATGCAAGCTCACAACAAGTGTATAACCGCTTAGTTGAATTT
AAAAAAGGCTCAACGGATATTGAACCAGCTTTAGCTGAAAGTTGGGAAATTAGCGATGATGGTTTAAGTTATACTTTTCA
TTTAAGAAAGGGTGTTAAATTCCATACAACAAAAGAATTTACCCCGACACGTGATTTTAATGCAGATGATGTTGTATTTT
CATTCCAGCGTCAGTTAGATCCAAATCATCCATATCACAATGTATCTAAGGGGACTTATCCATATTTTAAAGCAATGAAA
TTCCCTGAATTGTTGAAATCAGTGGAGAAAGTAGACGATAACACAATTCGTATTACCTTAAACAAGACAGATGCGACTTT
CTTGGCTAGTCTTGGTATGGATTTTATTTCTATTTATTCTGCAGAATATGCTGATTCAATGCTGAAAGCGGGTAAACCAG
AAACACTTGATAGTCGCCCAGTGGGGACAGGCCCTTTTGTTTTTGTGGATTATAAAACAGATCAAGCCATACAATATGTT
GCGCATGAAAATTATTGGAAAGGTAGAACACCTTTAGATCGTTTAGTCATTAGCATTGTGCCTGATGCAACAACACGTTA
TGCAAAATTACAGGCGGGTACTTGCGATTTAATTTTATTCCCAAATGTAGCGGATTTAGCCAAAATGAAAACCGATCCAA
AAGTACAACTTTTGGAACAAAAAGGTTTGAACGTAGCGTATATCGCATTCAATACCGAAAAAGCACCGTTTGATAATGTC
AAAGTGCGCCAAGCGTTGAATTACGCAGTGGATAAAAAAGCGATTATTGAAGCGGTTTATCAAGGCGCAGGAACATCAGC
TAAAAACCCACTTCCTCCAACAATTTGGAGTTATAATGATGAAATCCAAGATTATCCGTACGATCCAGAAAAAGCAAAAC
AACTTTTAGCAGAAGCGGGTTATCCAAATGGTTTTGAAACTGATTTCTGGATTCAACCTGTTATTCGTGCTTCTAATCCA
AATCCAAAACGTATGGCTGAATTAATTATGGCGGATTGGGCGAAAATTGGTGTAAAAACTAACCCAGTGACTTATGAATG
GGCTGATTATAGAAAACGAGCAAAAGAGGGAGAATTAACTGCGGGTATCTTTGGTTGGTCTGGCGACAATGGCGATCCTG
ATAATTTCTTATCCCCATTATTAGGTAGCTCAAATATAGGTAATTCTAATATGGCACGTTTCAATAATTCAGAATTTGAT
GCTTTACTCAATGAGGCTATTGGATTAACCAATAAGGAAGAACGTGCGAAACTTTATAAACAAGCTCAAGTTATTGTCCA
TAATCAAGCACCTTGGATTCCAGTTGCCCACTCTGTTGGTTTTGCACCACTTAGTCCTCGTGTAAAAGGTTATGTACAAA
GCCCATTTGGCTATGACGCTTTTTATGGTGTGAGTGTTGATGGTAAATAA

Upstream 100 bases:

>100_bases
AAGGGAAATTTGCTTATATCTTATTGATATTTCTTGTTGGTGGAGATAGCTCCATCGTTTAACCATAAATGGTAGGGCAT
TCCCTGCCTAACATTGAGGT

Downstream 100 bases:

>100_bases
TTCATATTGATTTACTTATTTTAAGCCCTTATTTATAAGGGCTTTTTATTTATCAAGGATTATTCTGTAAAAAATATGTT
AAATAACTTTAACTTGAGTA

Product: heme-binding lipoprotein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALIIEGTSYNASSQQVYNRLVEF
KKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEFTPTRDFNADDVVFSFQRQLDPNHPYHNVSKGTYPYFKAMK
FPELLKSVEKVDDNTIRITLNKTDATFLASLGMDFISIYSAEYADSMLKAGKPETLDSRPVGTGPFVFVDYKTDQAIQYV
AHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILFPNVADLAKMKTDPKVQLLEQKGLNVAYIAFNTEKAPFDNV
KVRQALNYAVDKKAIIEAVYQGAGTSAKNPLPPTIWSYNDEIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPVIRASNP
NPKRMAELIMADWAKIGVKTNPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFD
ALLNEAIGLTNKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDAFYGVSVDGK

Sequences:

>Translated_549_residues
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALIIEGTSYNASSQQVYNRLVEF
KKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEFTPTRDFNADDVVFSFQRQLDPNHPYHNVSKGTYPYFKAMK
FPELLKSVEKVDDNTIRITLNKTDATFLASLGMDFISIYSAEYADSMLKAGKPETLDSRPVGTGPFVFVDYKTDQAIQYV
AHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILFPNVADLAKMKTDPKVQLLEQKGLNVAYIAFNTEKAPFDNV
KVRQALNYAVDKKAIIEAVYQGAGTSAKNPLPPTIWSYNDEIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPVIRASNP
NPKRMAELIMADWAKIGVKTNPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFD
ALLNEAIGLTNKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDAFYGVSVDGK
>Mature_549_residues
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALIIEGTSYNASSQQVYNRLVEF
KKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEFTPTRDFNADDVVFSFQRQLDPNHPYHNVSKGTYPYFKAMK
FPELLKSVEKVDDNTIRITLNKTDATFLASLGMDFISIYSAEYADSMLKAGKPETLDSRPVGTGPFVFVDYKTDQAIQYV
AHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILFPNVADLAKMKTDPKVQLLEQKGLNVAYIAFNTEKAPFDNV
KVRQALNYAVDKKAIIEAVYQGAGTSAKNPLPPTIWSYNDEIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPVIRASNP
NPKRMAELIMADWAKIGVKTNPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFD
ALLNEAIGLTNKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDAFYGVSVDGK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=518, Percent_Identity=54.4401544401544, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1787551, Length=535, Percent_Identity=35.8878504672897, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1787052, Length=443, Percent_Identity=31.8284424379233, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1787762, Length=505, Percent_Identity=27.5247524752475, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1789887, Length=472, Percent_Identity=26.6949152542373, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789397, Length=512, Percent_Identity=28.125, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787495, Length=462, Percent_Identity=25.7575757575758, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87081878, Length=467, Percent_Identity=25.9100642398287, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60905; Mature: 60905

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALI
CEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCEEE
IEGTSYNASSQQVYNRLVEFKKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEF
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCCEEEECCCC
TPTRDFNADDVVFSFQRQLDPNHPYHNVSKGTYPYFKAMKFPELLKSVEKVDDNTIRITL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCEEEEEE
NKTDATFLASLGMDFISIYSAEYADSMLKAGKPETLDSRPVGTGPFVFVDYKTDQAIQYV
ECCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
AHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILFPNVADLAKMKTDPKVQLLEQ
HHCCCCCCCCCHHHHHEEECCCCCCCEEEEECCCEEEEECCCHHHHHHCCCCCCHHHHHH
KGLNVAYIAFNTEKAPFDNVKVRQALNYAVDKKAIIEAVYQGAGTSAKNPLPPTIWSYND
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPVIRASNPNPKRMAELIMADWAKIGVKT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECEEEECCCCCHHHHHHHHHHHHHHCCCCC
NPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFD
CCCEEEHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
ALLNEAIGLTNKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDA
HHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCEEEHHCCCCCCCCCCHHHEEECCCCCCE
FYGVSVDGK
EEEEEECCC
>Mature Secondary Structure
MLMKLKATLTLAAATLVLAACDQSSSANKSTAQTEAKSSSNNTFVYCTAKAPLGFSPALI
CEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCEEE
IEGTSYNASSQQVYNRLVEFKKGSTDIEPALAESWEISDDGLSYTFHLRKGVKFHTTKEF
EECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCCEEEECCCC
TPTRDFNADDVVFSFQRQLDPNHPYHNVSKGTYPYFKAMKFPELLKSVEKVDDNTIRITL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCEEEEEE
NKTDATFLASLGMDFISIYSAEYADSMLKAGKPETLDSRPVGTGPFVFVDYKTDQAIQYV
ECCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHH
AHENYWKGRTPLDRLVISIVPDATTRYAKLQAGTCDLILFPNVADLAKMKTDPKVQLLEQ
HHCCCCCCCCCHHHHHEEECCCCCCCEEEEECCCEEEEECCCHHHHHHCCCCCCHHHHHH
KGLNVAYIAFNTEKAPFDNVKVRQALNYAVDKKAIIEAVYQGAGTSAKNPLPPTIWSYND
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EIQDYPYDPEKAKQLLAEAGYPNGFETDFWIQPVIRASNPNPKRMAELIMADWAKIGVKT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECEEEECCCCCHHHHHHHHHHHHHHCCCCC
NPVTYEWADYRKRAKEGELTAGIFGWSGDNGDPDNFLSPLLGSSNIGNSNMARFNNSEFD
CCCEEEHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
ALLNEAIGLTNKEERAKLYKQAQVIVHNQAPWIPVAHSVGFAPLSPRVKGYVQSPFGYDA
HHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCEEEHHCCCCCCCCCCHHHEEECCCCCCE
FYGVSVDGK
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]