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The map label for this gene is cpxR

Identifier: 16272778

GI number: 16272778

Start: 887135

End: 887818

Strand: Reverse

Name: cpxR

Synonym: HI0837

Alternate gene names: 16272778

Gene position: 887818-887135 (Counterclockwise)

Preceding gene: 16272779

Following gene: 16272776

Centisome position: 48.51

GC content: 34.5

Gene sequence:

>684_bases
ATGTCAAAACTCTTACTCGTTGATGATGATATTGAATTAACTGAACTACTTTCTACACTTTTAGAACTTGAGGGTTTTGA
CGTTGAAACTGCAAATAATGGATTAGAAGCATTACAAAAACTCAATGAAAGCTATAAACTGGTTTTACTTGATGTAATGA
TGCCAAAGTTAAATGGTATCGAAACATTAAAAGAAATTCGTAAAGTCTCTAACGTGCCAGTGATGATGCTAACAGCAAGA
GGCGAAGACATTGATCGCGTATTAGGCTTAGAATTGGGAGCGGATGATTGTTTACCCAAGCCTTTTAACGATCGTGAACT
TATTGCAAGAATTAAGGCGATTTTGCGTCGTAGTGCATCTCCTTCAAATAATATATCAAATGTAGAAATCCTTTCTTTTG
ACGGAATTACTCTCCACTTTTCTCACGGAATTGCAACCTATAATGAAGAAAATCTAAATTTAACGGATTATGAATTTAAG
ATTCTTTGTTTATTGCTTAAATCTAAGGGAAATGTGGTAAGTCGAGAAGAATTAAGTTTAGAAGTAATGGAAAAACCGCT
CACTCCATTTGACCGTTCTCTTGATATGCACATCTCTAATTTAAGACGCAAATTACCAAAACGAAAAAACAAGCCCTCTT
GGTTTAAAACTTTACGCGGAAAAGGATACGCTTTAGTTACCTAA

Upstream 100 bases:

>100_bases
AAACAGGTGAGAAACCAAAATCAAGCTGGTGGAAATTCTGGAAATAATCTTTTTATTTTCACCACACTACAATAAGAATA
ATTGGTAAAAGGAATCTCCA

Downstream 100 bases:

>100_bases
TTTTTATGAAATTAGGTTATTTTTTCAATTTAAATCAACTCACTATCCAAACATTTCTTATGTTTTGGTTTTCTTTTTTT
CATAATGATGAGCCTTGTGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKLNESYKLVLLDVMMPKLNGIETLKEIRKVSNVPVMMLTAR
GEDIDRVLGLELGADDCLPKPFNDRELIARIKAILRRSASPSNNISNVEILSFDGITLHFSHGIATYNEENLNLTDYEFK
ILCLLLKSKGNVVSREELSLEVMEKPLTPFDRSLDMHISNLRRKLPKRKNKPSWFKTLRGKGYALVT

Sequences:

>Translated_227_residues
MSKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKLNESYKLVLLDVMMPKLNGIETLKEIRKVSNVPVMMLTAR
GEDIDRVLGLELGADDCLPKPFNDRELIARIKAILRRSASPSNNISNVEILSFDGITLHFSHGIATYNEENLNLTDYEFK
ILCLLLKSKGNVVSREELSLEVMEKPLTPFDRSLDMHISNLRRKLPKRKNKPSWFKTLRGKGYALVT
>Mature_226_residues
SKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKLNESYKLVLLDVMMPKLNGIETLKEIRKVSNVPVMMLTARG
EDIDRVLGLELGADDCLPKPFNDRELIARIKAILRRSASPSNNISNVEILSFDGITLHFSHGIATYNEENLNLTDYEFKI
LCLLLKSKGNVVSREELSLEVMEKPLTPFDRSLDMHISNLRRKLPKRKNKPSWFKTLRGKGYALVT

Specific function: Member of a two-component regulatory system

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=59.1304347826087, Blast_Score=246, Evalue=6e-67,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.117903930131, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.8260869565217, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=37.9464285714286, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=35.1351351351351, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=33.7777777777778, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=33.1858407079646, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.7777777777778, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=36.1233480176211, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.304347826087, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.9130434782609, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=27.8026905829596, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=27.0042194092827, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=38.5321100917431, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=38.655462184874, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=38.7096774193548, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=34.1666666666667, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CPXR_HAEIN (P44895)

Other databases:

- EMBL:   L42023
- PIR:   C64159
- RefSeq:   NP_438997.1
- ProteinModelPortal:   P44895
- SMR:   P44895
- GeneID:   949851
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0837
- NMPDR:   fig|71421.1.peg.805
- TIGR:   HI_0837
- HOGENOM:   HBG753323
- OMA:   ATYNEEN
- ProtClustDB:   CLSK808453
- BioCyc:   HINF71421:HI_0837-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 25727; Mature: 25596

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKLNESYKLVLLDVMMPKLNGI
CCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCH
ETLKEIRKVSNVPVMMLTARGEDIDRVLGLELGADDCLPKPFNDRELIARIKAILRRSAS
HHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PSNNISNVEILSFDGITLHFSHGIATYNEENLNLTDYEFKILCLLLKSKGNVVSREELSL
CCCCCCEEEEEEECCEEEEEECCEEEECCCCCCCCCHHHHHHEEEHHCCCCCCCHHHHHH
EVMEKPLTPFDRSLDMHISNLRRKLPKRKNKPSWFKTLRGKGYALVT
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SKLLLVDDDIELTELLSTLLELEGFDVETANNGLEALQKLNESYKLVLLDVMMPKLNGI
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCH
ETLKEIRKVSNVPVMMLTARGEDIDRVLGLELGADDCLPKPFNDRELIARIKAILRRSAS
HHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PSNNISNVEILSFDGITLHFSHGIATYNEENLNLTDYEFKILCLLLKSKGNVVSREELSL
CCCCCCEEEEEEECCEEEEEECCEEEECCCCCCCCCHHHHHHEEEHHCCCCCCCHHHHHH
EVMEKPLTPFDRSLDMHISNLRRKLPKRKNKPSWFKTLRGKGYALVT
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800