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The map label for this gene is mglC

Identifier: 16272765

GI number: 16272765

Start: 876143

End: 877153

Strand: Direct

Name: mglC

Synonym: HI0824

Alternate gene names: 16272765

Gene position: 876143-877153 (Clockwise)

Preceding gene: 16272764

Following gene: 16272766

Centisome position: 47.87

GC content: 38.38

Gene sequence:

>1011_bases
ATGAGTGCCTTAGAAAAAAACAAATCCTTTGATCTCTTAAAACAAAATGCGATTTATTTTGTGTTATTGATTTTGCTCGG
CATCATCATTGCACAAGATCCGACATTCTTAAATTTAGTCAATTTCAGTAACATCTTAACCCAATCTTCTGTACGTTTAA
TTATTGCTTTAGGGGTTGCGGGTTTATTGATTACACAAGGGACTGACTTATCTGCAGGTCGTCAAGTTGGTTTGGCTGCA
GTTATCTCTGCAACAATGTTGCAATCAATGGAAAATATTAACCGCGTGTTCCCTGAAATGGGACAAATACCAATTCCAGT
GGTTATTCTCGCAGTTTGTGCTATCGGTGCAGTAATTGGTTTAGTGAATGGTTTAGTTATCGCTTACTTAAATGTAACTC
CATTCATCGCAACCATGGGTACAATGATCATCATATATGGTTTCAACTCACTATACTATGATGCTGTAGGTGGTTCTCCA
ATCGCAGGTTTTAGTGAAAATTTCTCAACATTTGCTCAAGGATTCTTCCGAGTCGGCAGCTTTAAACTCTCTTACATCAC
GATTTATGCAGCTATTGCAGCATTATTAGTATGGATTATGTGGAACAAAACTCGTTTCGGTAAAAACGTATTTGCTATCG
GTGGTAACCCAGAAGCAGCTAAAGTATCTGGTGTAAACGTTGCACGTAACTTAGTTGCAATCTATATGATTGCAGGTATG
TTCTATGCCTTTGGTGGTATGCTTGAAGCGGGTCGTATCGGTTCTGCAACTAACAACTTAGGTTTTATGTATGAATTAGA
TGCTATCGCCGCTTGCGTAGTGGGTGGTGTATCTTTTGCTGGTGGGGTAGGTACAGTAATTGGTGTTATCACTGGGGTTA
TTATCTTTACTGTTATCAACTACGGTTTAACTTACATCGGTGTAAACCCTTACTGGCAATACATCATTAAAGGTAGCATT
ATCATTCTAGCGGTAGCCATTGACTCGTTAAAATATGCGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
AGTAACGGTAAATTAGCAGGTATCGTTGAAAGCGCAAAAACATCGCAAGAAGAAATTTTGCAACTCGCGGCAAAATATTT
ATAAACATAAGGAATGAATT

Downstream 100 bases:

>100_bases
AGCTGACGCAATCTTAATAAAATGAATGAAAAGTGGGCAAATTTGTCCACTTTTGTTTTATCTATTCAATTCTGAATTAA
GGATATTTATGCAATAATCG

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSALEKNKSFDLLKQNAIYFVLLILLGIIIAQDPTFLNLVNFSNILTQSSVRLIIALGVAGLLITQGTDLSAGRQVGLAA
VISATMLQSMENINRVFPEMGQIPIPVVILAVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIIYGFNSLYYDAVGGSP
IAGFSENFSTFAQGFFRVGSFKLSYITIYAAIAALLVWIMWNKTRFGKNVFAIGGNPEAAKVSGVNVARNLVAIYMIAGM
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVITGVIIFTVINYGLTYIGVNPYWQYIIKGSI
IILAVAIDSLKYAKKK

Sequences:

>Translated_336_residues
MSALEKNKSFDLLKQNAIYFVLLILLGIIIAQDPTFLNLVNFSNILTQSSVRLIIALGVAGLLITQGTDLSAGRQVGLAA
VISATMLQSMENINRVFPEMGQIPIPVVILAVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIIYGFNSLYYDAVGGSP
IAGFSENFSTFAQGFFRVGSFKLSYITIYAAIAALLVWIMWNKTRFGKNVFAIGGNPEAAKVSGVNVARNLVAIYMIAGM
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVITGVIIFTVINYGLTYIGVNPYWQYIIKGSI
IILAVAIDSLKYAKKK
>Mature_335_residues
SALEKNKSFDLLKQNAIYFVLLILLGIIIAQDPTFLNLVNFSNILTQSSVRLIIALGVAGLLITQGTDLSAGRQVGLAAV
ISATMLQSMENINRVFPEMGQIPIPVVILAVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIIYGFNSLYYDAVGGSPI
AGFSENFSTFAQGFFRVGSFKLSYITIYAAIAALLVWIMWNKTRFGKNVFAIGGNPEAAKVSGVNVARNLVAIYMIAGMF
YAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVITGVIIFTVINYGLTYIGVNPYWQYIIKGSII
ILAVAIDSLKYAKKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=79.1666666666667, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1790191, Length=322, Percent_Identity=35.0931677018634, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1790524, Length=333, Percent_Identity=29.7297297297297, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789992, Length=130, Percent_Identity=46.1538461538462, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693152, Length=338, Percent_Identity=30.4733727810651, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788896, Length=306, Percent_Identity=32.3529411764706, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787794, Length=291, Percent_Identity=29.8969072164948, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787793, Length=305, Percent_Identity=25.9016393442623, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=27.9605263157895, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693214, Length=268, Percent_Identity=29.8507462686567, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MGLC_HAEIN (P44885)

Other databases:

- EMBL:   L42023
- PIR:   I64096
- RefSeq:   NP_438984.1
- GeneID:   949838
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0824
- TIGR:   HI_0824
- HOGENOM:   HBG663180
- OMA:   IAIIFVW
- ProtClustDB:   PRK09478
- BioCyc:   HINF71421:HI_0824-MONOMER
- InterPro:   IPR001851

Pfam domain/function: PF02653 BPD_transp_2

EC number: NA

Molecular weight: Translated: 35728; Mature: 35597

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd6e4e54)-; HASH(0xd12f688)-; HASH(0xd07b748)-; HASH(0xd8954b8)-; HASH(0xd1e615c)-; HASH(0xd481804)-; HASH(0xd6cee24)-; HASH(0xd6693d0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALEKNKSFDLLKQNAIYFVLLILLGIIIAQDPTFLNLVNFSNILTQSSVRLIIALGVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GLLITQGTDLSAGRQVGLAAVISATMLQSMENINRVFPEMGQIPIPVVILAVCAIGAVIG
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LVNGLVIAYLNVTPFIATMGTMIIIYGFNSLYYDAVGGSPIAGFSENFSTFAQGFFRVGS
HHHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEECCCCCCCCCCCCCHHHHHHHHHHHCC
FKLSYITIYAAIAALLVWIMWNKTRFGKNVFAIGGNPEAAKVSGVNVARNLVAIYMIAGM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVITGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGSIIILAVAIDSLKYAKKK
CCCEEEECCHHHHHHHCCCCEEEEEHHHHHHHHCCH
>Mature Secondary Structure 
SALEKNKSFDLLKQNAIYFVLLILLGIIIAQDPTFLNLVNFSNILTQSSVRLIIALGVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GLLITQGTDLSAGRQVGLAAVISATMLQSMENINRVFPEMGQIPIPVVILAVCAIGAVIG
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LVNGLVIAYLNVTPFIATMGTMIIIYGFNSLYYDAVGGSPIAGFSENFSTFAQGFFRVGS
HHHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEECCCCCCCCCCCCCHHHHHHHHHHHCC
FKLSYITIYAAIAALLVWIMWNKTRFGKNVFAIGGNPEAAKVSGVNVARNLVAIYMIAGM
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVITGVIIFTVIN
HHHHHCHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGSIIILAVAIDSLKYAKKK
CCCEEEECCHHHHHHHCCCCEEEEEHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800