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The map label for this gene is frr [H]

Identifier: 16272749

GI number: 16272749

Start: 857310

End: 857867

Strand: Reverse

Name: frr [H]

Synonym: HI0808

Alternate gene names: 16272749

Gene position: 857867-857310 (Counterclockwise)

Preceding gene: 16272750

Following gene: 16272748

Centisome position: 46.87

GC content: 37.46

Gene sequence:

>558_bases
ATGCTTAACCAAATTAAAAAAGATGCTCAAGATCGTATGGAAAAAAGCCTTGAAGCATTAAAAGGTCATATTTCAAAAAT
TCGTACTGGTCGTGCTCAACCGAGTTTACTTGATGCAATTCAAGTTGAATATTACGGTGCGGCGACCCCACTTCGCCAAT
TAGCAAACGTAGTGGCAGAAGATGCGCGTACTTTAGCCGTAACTGTGTTTGATCGTTCTTTAATCTCTGCGGTAGAAAAA
GCAATTTTAACCTCAGATTTAGGTTTAAACCCATCTTCAGCGGGTACCACAATCCGTGTTCCGCTTCCGCCATTAACAGA
AGAACGTCGTCGCGATTTAATCAAAATTGTAAAAGGCGAAGGTGAACAAGGTAAAGTTGCGGTTCGTAATGTGCGTCGTG
ATGCGAATGATAAAATCAAAGCATTATTAAAAGACAAAGAAATCAGCGAAAACGAACAACATAAAGCAGAAGAAGAAATC
CAAAAAATCACAGATATTTACATTAAAAAAGTAGATGAAGTATTAGCGGATAAAGAAAAAGAATTAATGGATTTCTAA

Upstream 100 bases:

>100_bases
TTTTTTATCTGTTTTCAAGCTGATAAATGTATTCAAAAATTTAAAAAAATCCAGTAAAATCACGGCGTTCTAACTTTCAT
CAATTAAAAAGGACAATGCA

Downstream 100 bases:

>100_bases
TCATAAAAAATGCGAAAGGCAGACAGTTTTGTCTGCCTTTATTTTATTAGGTATGCAAATTTAGACGTACCAATGAAAAT
GTAATCAACAAAAGTGCGGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEK
AILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGEGEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEI
QKITDIYIKKVDEVLADKEKELMDF

Sequences:

>Translated_185_residues
MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEK
AILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGEGEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEI
QKITDIYIKKVDEVLADKEKELMDF
>Mature_185_residues
MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAEDARTLAVTVFDRSLISAVEK
AILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGEGEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEI
QKITDIYIKKVDEVLADKEKELMDF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=31.8435754189944, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=68.6486486486486, Blast_Score=265, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20729; Mature: 20729

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DARTLAVTVFDRSLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
GEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVDEVLADKEK
CCCCHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELMDF
HHHCC
>Mature Secondary Structure
MLNQIKKDAQDRMEKSLEALKGHISKIRTGRAQPSLLDAIQVEYYGAATPLRQLANVVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
DARTLAVTVFDRSLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
GEQGKVAVRNVRRDANDKIKALLKDKEISENEQHKAEEEIQKITDIYIKKVDEVLADKEK
CCCCHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELMDF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA