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The map label for this gene is truD [H]

Identifier: 16272642

GI number: 16272642

Start: 747228

End: 748247

Strand: Direct

Name: truD [H]

Synonym: HI0701

Alternate gene names: 16272642

Gene position: 747228-748247 (Clockwise)

Preceding gene: 16272636

Following gene: 16272643

Centisome position: 40.83

GC content: 40.49

Gene sequence:

>1020_bases
ATGCTCGAACAACTCCCTTATTTAGCATTAAAAACTCCGCCAAAAACCACCGCACTTTTAAAGGCTGAATGTGCGGATTT
TATTGTAAAAGAGCATTTAGGCTATGAAATGTCAGGTGACGGTGAGTTTGTTGCGTTGTATGTACGCAAAACAGATTGCA
ACACCTTATTTGTTGGCGAAAAATTAGCTAAATTTGCTGGTGTTTCTGAACGCAATATGGGATATGCAGGGTTGAAAGAT
CGTCGAGCGGTGACAGAACAATGGTTTTGCTTGCAAATGCCAGGAATGGAAACGCCCGATTTCAGTCAATTTGAATTAGA
TGGCGTAGAGATTTTAACGGTTACTCGACATAACCGAAAAATTCGCACGGGTAGCCTTGAAGGAAATTATTTCGATATTT
TATTACGCGGTGCAGAAGAATCTGATGAGCTTAAAGCGCGGCTGGATTTTGTGGCAAATTTTGGTTTCCCCAATTATTTT
ACGGAACAACGTTTTGGTCGGGATGGCCATAACCTCACGCAAGCCTTGCGTTGGGCTCAAGGGGAAATCAAGGTAAAAGA
TCGCAAAAAACGCAGTTTTTATCTTTCCGCCGCGCGCAGTGAAATTTTTAATTTAGTTGTGGCTGCGCGTATCGAAAAGA
GCACAATAAATCAAGTTTTACCAAATGATATTGTGCAATTAGCAGGTTCGCACAGTTGGTTCAAAGCGGATGAAAAAGAA
GACTTAACTGCCTTACAAGTGCGGTTAGAAAATCAAGATATTTTGCTTACTGCCCCTTTAATTGGCGAAGATATTTTAGC
AGCAAGCGAGATTGAAAATGAAATCGTAAATCAACATTCAGCTTTCGATCCTTTAATGAAACAAGAAAGAATGAAGGCTG
CACGTCGCCCATTATTGATGAAAGCAAAAGGGTTTTCTTGGGCATTTGAGCCAGAAGGCTTGCGTTTAAAATTTTATTTG
CCAGCAGGCAGTTATGCCACGGCATTAGTTCGTGAGTTAGTAAATTACACAGAAGAATAA

Upstream 100 bases:

>100_bases
CCTTCAACAAGAACAAAAGTGCGGTTATTTTAGTGGATAAATCACGAAAAGTCGCATAGAATTTCGCACAATTATTTTCG
ATAAAAAAGAGCCCTTAACT

Downstream 100 bases:

>100_bases
GGAAATATAATGCGAATTTTAGTTAGTAATGATGATGGTTTTCACGCGGAAGGCATTCAGGTTTTAGCAACAGAATTAAG
AAAAATTGCAGAAGTCATTA

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGEKLAKFAGVSERNMGYAGLKD
RRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRKIRTGSLEGNYFDILLRGAEESDELKARLDFVANFGFPNYF
TEQRFGRDGHNLTQALRWAQGEIKVKDRKKRSFYLSAARSEIFNLVVAARIEKSTINQVLPNDIVQLAGSHSWFKADEKE
DLTALQVRLENQDILLTAPLIGEDILAASEIENEIVNQHSAFDPLMKQERMKAARRPLLMKAKGFSWAFEPEGLRLKFYL
PAGSYATALVRELVNYTEE

Sequences:

>Translated_339_residues
MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGEKLAKFAGVSERNMGYAGLKD
RRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRKIRTGSLEGNYFDILLRGAEESDELKARLDFVANFGFPNYF
TEQRFGRDGHNLTQALRWAQGEIKVKDRKKRSFYLSAARSEIFNLVVAARIEKSTINQVLPNDIVQLAGSHSWFKADEKE
DLTALQVRLENQDILLTAPLIGEDILAASEIENEIVNQHSAFDPLMKQERMKAARRPLLMKAKGFSWAFEPEGLRLKFYL
PAGSYATALVRELVNYTEE
>Mature_339_residues
MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGEKLAKFAGVSERNMGYAGLKD
RRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRKIRTGSLEGNYFDILLRGAEESDELKARLDFVANFGFPNYF
TEQRFGRDGHNLTQALRWAQGEIKVKDRKKRSFYLSAARSEIFNLVVAARIEKSTINQVLPNDIVQLAGSHSWFKADEKE
DLTALQVRLENQDILLTAPLIGEDILAASEIENEIVNQHSAFDPLMKQERMKAARRPLLMKAKGFSWAFEPEGLRLKFYL
PAGSYATALVRELVNYTEE

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=341, Percent_Identity=43.9882697947214, Blast_Score=287, Evalue=8e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 38549; Mature: 38549

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGE
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCCEEEHHH
KLAKFAGVSERNMGYAGLKDRRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRK
HHHHHCCCCCCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCEEECCEEEEEEEECCCE
IRTGSLEGNYFDILLRGAEESDELKARLDFVANFGFPNYFTEQRFGRDGHNLTQALRWAQ
EEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCC
GEIKVKDRKKRSFYLSAARSEIFNLVVAARIEKSTINQVLPNDIVQLAGSHSWFKADEKE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
DLTALQVRLENQDILLTAPLIGEDILAASEIENEIVNQHSAFDPLMKQERMKAARRPLLM
CCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
KAKGFSWAFEPEGLRLKFYLPAGSYATALVRELVNYTEE
EECCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEQLPYLALKTPPKTTALLKAECADFIVKEHLGYEMSGDGEFVALYVRKTDCNTLFVGE
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCCEEEHHH
KLAKFAGVSERNMGYAGLKDRRAVTEQWFCLQMPGMETPDFSQFELDGVEILTVTRHNRK
HHHHHCCCCCCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCEEECCEEEEEEEECCCE
IRTGSLEGNYFDILLRGAEESDELKARLDFVANFGFPNYFTEQRFGRDGHNLTQALRWAQ
EEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCC
GEIKVKDRKKRSFYLSAARSEIFNLVVAARIEKSTINQVLPNDIVQLAGSHSWFKADEKE
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
DLTALQVRLENQDILLTAPLIGEDILAASEIENEIVNQHSAFDPLMKQERMKAARRPLLM
CCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
KAKGFSWAFEPEGLRLKFYLPAGSYATALVRELVNYTEE
EECCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA