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The map label for this gene is lex1

Identifier: 16272494

GI number: 16272494

Start: 570690

End: 571598

Strand: Reverse

Name: lex1

Synonym: HI0550

Alternate gene names: 16272494

Gene position: 571598-570690 (Counterclockwise)

Preceding gene: 16272497

Following gene: 30995385

Centisome position: 31.23

GC content: 28.16

Gene sequence:

>909_bases
ATGAGTGCTATTGAAAATATTGTCATTAGTATGGAAAATGCAACTGAACGTCGCAAACATATTACTAAGCAATTTGAATC
AAAAAAACTTTCATTTAGTTTCTTTAATGCGTACACTTATCAATCAATCAATCAATCAATCAATCAATCAATCAATCAAT
CAATCAATCAATCAATCAATCAATCAATCAATCAATCAATCAATCAATCAAACTCCATATTACATAATATAGAGGAATCT
AGAATACTTACTAAAGGAGAAAAAGGCTGTTTAATTAGCCATTTCTTATTATGGAATAAGTGTGTGAATGAAAATTTTGA
ATATCTCAAAATTTTTGAAGATGATGTAATTCTTGGCGAGAATGCGGAAGTATTTTTGAACCAAAATGAATGGTTAAAAA
CACGTTTTGATTTTAATGATATTTTTATTATTCGTTTAGAAACTTTTTTACAGCCAGTTAAACTTGAGAAACAAACTAAA
ATTCCACCTTTTAATTCTAGGAACTTTGATATTTTAAAATCAACTCACTGGGGGACGGCAGGTTATATTATTTCTCAAGG
TGCGGCTAAATATGTAATTGAATATTTAAAGAATATTCCTTCTGATGAAATTGTTGCAGTTGATGAACTTATTTTTAATA
AATTAGTTGATGTTGATAATTATATTGTCTATCAACTGAATCCAGCAATTTGTATTCAAGAACTCCAAGCGAATCAAAGT
AAAAGTGTATTAACAAGCGGATTGGAAAAAGAACGACAAAAACGTTCAAAAATCCGTAAGAAAAAGACATTGAAACAGCG
TTTAACTCGGATAAAAGAAAATATTATACGAGCTTTAAATAGAAAAAAATGGAAAGAACAACAACGTATTAAAGAAATGC
AAGGTAAAGAAATTGTTCGTTTTATGTAG

Upstream 100 bases:

>100_bases
AAATAAATTTTGAAAATTTTAACACAGACTTTTATTGTTGATTTATTCTTTTTGTATAGTAGAATGCGAAAAATTTAGTT
ATTTCCATTTTTATTTAAAT

Downstream 100 bases:

>100_bases
AAAGCCAAGGTGTAACAAGGGTTACACCTTTTTATTATTTTTACTCTTCTGAATCTAAGATTTCATCTTTATTGACATCT
GCTGGTGGATTATCCGCTAA

Product: lipooligosaccharide biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSINQSINQSINQSINQSINQSINQSINQSNSILHNIEES
RILTKGEKGCLISHFLLWNKCVNENFEYLKIFEDDVILGENAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTK
IPPFNSRNFDILKSTHWGTAGYIISQGAAKYVIEYLKNIPSDEIVAVDELIFNKLVDVDNYIVYQLNPAICIQELQANQS
KSVLTSGLEKERQKRSKIRKKKTLKQRLTRIKENIIRALNRKKWKEQQRIKEMQGKEIVRFM

Sequences:

>Translated_302_residues
MSAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSINQSINQSINQSINQSINQSINQSINQSNSILHNIEES
RILTKGEKGCLISHFLLWNKCVNENFEYLKIFEDDVILGENAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTK
IPPFNSRNFDILKSTHWGTAGYIISQGAAKYVIEYLKNIPSDEIVAVDELIFNKLVDVDNYIVYQLNPAICIQELQANQS
KSVLTSGLEKERQKRSKIRKKKTLKQRLTRIKENIIRALNRKKWKEQQRIKEMQGKEIVRFM
>Mature_301_residues
SAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSINQSINQSINQSINQSINQSINQSINQSNSILHNIEESR
ILTKGEKGCLISHFLLWNKCVNENFEYLKIFEDDVILGENAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTKI
PPFNSRNFDILKSTHWGTAGYIISQGAAKYVIEYLKNIPSDEIVAVDELIFNKLVDVDNYIVYQLNPAICIQELQANQSK
SVLTSGLEKERQKRSKIRKKKTLKQRLTRIKENIIRALNRKKWKEQQRIKEMQGKEIVRFM

Specific function: Involved in extracellular lipooligosaccharide (LOS) biosynthesis and virulence expression. Involved in the synthesis of the oligosaccharide moiety of the LOS molecule by adding GalNAc

COG id: COG3306

COG function: function code M; Glycosyltransferase involved in LPS biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 25 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LIC2A_HAEIN (Q03974)

Other databases:

- EMBL:   L42023
- EMBL:   X56903
- EMBL:   L19441
- PIR:   A64077
- RefSeq:   NP_438708.1
- GeneID:   949673
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0550
- NMPDR:   fig|71421.1.peg.521
- TIGR:   HI_0550
- HOGENOM:   HBG495618
- OMA:   NIVISME
- ProtClustDB:   CLSK808424
- BioCyc:   HINF71421:HI_0550-MONOMER
- GO:   GO:0009405
- InterPro:   IPR002654
- PANTHER:   PTHR10730:SF2

Pfam domain/function: PF01755 Glyco_transf_25

EC number: NA

Molecular weight: Translated: 35490; Mature: 35359

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSINQSINQSINQSINQSIN
CCCHHHHHEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSINQSINQSNSILHNIEESRILTKGEKGCLISHFLLWNKCVNENFEYLKIFEDDVILGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECC
NAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTKIPPFNSRNFDILKSTHWGTA
CCEEEECCCCCEEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCH
GYIISQGAAKYVIEYLKNIPSDEIVAVDELIFNKLVDVDNYIVYQLNPAICIQELQANQS
HHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCH
KSVLTSGLEKERQKRSKIRKKKTLKQRLTRIKENIIRALNRKKWKEQQRIKEMQGKEIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FM
CC
>Mature Secondary Structure 
SAIENIVISMENATERRKHITKQFESKKLSFSFFNAYTYQSINQSINQSINQSINQSIN
CCHHHHHEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSINQSINQSNSILHNIEESRILTKGEKGCLISHFLLWNKCVNENFEYLKIFEDDVILGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECC
NAEVFLNQNEWLKTRFDFNDIFIIRLETFLQPVKLEKQTKIPPFNSRNFDILKSTHWGTA
CCEEEECCCCCEEEECCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCH
GYIISQGAAKYVIEYLKNIPSDEIVAVDELIFNKLVDVDNYIVYQLNPAICIQELQANQS
HHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCH
KSVLTSGLEKERQKRSKIRKKKTLKQRLTRIKENIIRALNRKKWKEQQRIKEMQGKEIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 1956289; 7523834; 8861214