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The map label for this gene is deoD

Identifier: 16272462

GI number: 16272462

Start: 540760

End: 541476

Strand: Reverse

Name: deoD

Synonym: HI0518

Alternate gene names: 16272462

Gene position: 541476-540760 (Counterclockwise)

Preceding gene: 16272463

Following gene: 16272461

Centisome position: 29.59

GC content: 39.05

Gene sequence:

>717_bases
ATGACTCCACATATTAACGCGCCTGAAGGTGCATTTGCTGATGTTGTTTTAATGCCTGGCGATCCACTTCGTGCAAAATA
TATTGCAGAAACTTTTTTACAAGATGTTGTTGAAGTAACGAATGTTCGTAATATGCTTGGTTTTACTGGAACTTATAAAG
GTCGTAAAATTTCTATTATGGGGCACGGTATGGGGATTCCATCTTGCTCTATTTACGCGAAAGAATTAATCACTGAATAT
GGCGTGAAAAAAATTATCCGTGTAGGTTCTTGTGGCACTGTTCGTATGGACGTGAAAGTGCGCGATGTGATTATCGGTTT
AGGTGCATGTACTGATTCAAAAGTAAACCGTATTCGTTTCAAAGATAACGACTTTGCAGCTATTGCTGACTTTGATATGG
CACAAGCCGCTGTTCAAGCTGCAAAAGCAAAAGGTAAAGTCGTTCGTGTAGGTAATTTATTCTCGGCGGATTTATTCTAT
ACACCCGATGTGGAAATGTTCGATGTAATGGAAAAATACGGCATTTTAGGTGTGGAAATGGAAGCTGCTGGAATTTATGG
TGTGGCTGCAGAATATGGTGCAAAAGCATTAACGATTTGTACCGTGTCTGACCATATTCGTACTCACGAACAAACCACGG
CAGAAGAACGTCAATTAACATTCAATGATATGATTGAAATTGCGTTAGATTCAGTATTAATTGGTGATGCACTATAA

Upstream 100 bases:

>100_bases
GTGCTGCAGCACTTTAATTTATCTTAATCAATTAAAAAGTGCGGTAAAAAATGACCGCACTTTATTCATTTTTATTCATT
ATTAAAAATAAGGAAAAATT

Downstream 100 bases:

>100_bases
TATCTTCTATCGGATTTAAGAAGTGCTTGAAAAACAACCGCACTTTTTATATAATCCGTGCCCATTATGAGCCGTTTGTG
GCTCATATTTTTGTGTGGTG

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEY
GVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFY
TPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL

Sequences:

>Translated_238_residues
MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEY
GVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFY
TPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL
>Mature_237_residues
TPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEYG
VKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFYT
PDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=235, Percent_Identity=84.6808510638298, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1790265, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_HAEI8 (Q4QN30)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248227.1
- ProteinModelPortal:   Q4QN30
- SMR:   Q4QN30
- STRING:   Q4QN30
- GeneID:   3429954
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0644
- eggNOG:   COG0813
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- PhylomeDB:   Q4QN30
- ProtClustDB:   PRK05819
- BioCyc:   HINF281310:NTHI0644-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25885; Mature: 25754

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIM
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GHGMGIPSCSIYAKELITEYGVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRF
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCEEEEE
KDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFYTPDVEMFDVMEKYGILGVEM
CCCCEEEEECHHHHHHHHHHHHCCCCEEEECCEEECCEEECCCCHHHHHHHHHCCEEEEE
EAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL
ECCCEEEEHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIM
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GHGMGIPSCSIYAKELITEYGVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRF
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCEEEEE
KDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFYTPDVEMFDVMEKYGILGVEM
CCCCEEEEECHHHHHHHHHHHHCCCCEEEECCEEECCEEECCCCHHHHHHHHHCCEEEEE
EAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL
ECCCEEEEHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA