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The map label for this gene is atpB

Identifier: 16272432

GI number: 16272432

Start: 505478

End: 506266

Strand: Reverse

Name: atpB

Synonym: HI0485

Alternate gene names: 16272432

Gene position: 506266-505478 (Counterclockwise)

Preceding gene: 16272433

Following gene: 16272431

Centisome position: 27.66

GC content: 35.74

Gene sequence:

>789_bases
ATGTCTGGACAAACAACATCGGAATACATTAGCCACCATTTATCCTTTCTCAAAACAGGGGATGGATTTTGGAATGTTCA
TATAGATACGTTGTTCTTTTCTATTCTTGCTGCGGTTATTTTCCTATTTGTTTTTTCTCGAGTAGGGAAAAAAGCAACAA
CTGGCGTTCCAGGAAAAATGCAATGCTTAGTTGAAATTGTTGTGGAATGGGTTAATGGAATCGTGAAAGAAAATTTTCAT
GGTCCACGTAACGTAGTTGCGCCACTTGCATTAACAATTTTCTGTTGGGTATTCATCATGAATGCTATCGACTTAATTCC
TGTTGATTTCTTACCTCAATTTGCAGGTTTGTTCGGTATTCATTATCTTCGTGCAGTGCCGACAGCAGATATTAGCGCAA
CTTTGGGTATGTCCATTTGTGTTTTCTTTTTAATTCTTTTTTATACAATAAAATCTAAAGGATTCAAAGGTTTAGTTAAA
GAATATACGCTTCATCCATTCAATCATTGGGCGTTTATTCCTGTTAATTTTATTCTTGAAACGGTGACTTTATTGGCTAA
ACCAATTTCACTTGCCTTCCGTTTATTCGGTAACATGTATGCAGGGGAGTTGATCTTTATTCTTATCGCTGTAATGTATT
CCGCTAATATGGCCATTGCAGCATTAGGGATTCCGTTACATCTTGCTTGGGCTATTTTCCATATTTTGGTTATTACCTTG
CAGGCTTTCATCTTTATGATGTTGACGGTTGTTTATTTAAGTATTGCTTATAACAAAGCAGATCATTAA

Upstream 100 bases:

>100_bases
TGTTGGTTTTTTATTGGCATTAGTGCTGAATAATATTATTCCACTTATTCTCAATAAAATTTAACTTTGGGTTATTCTTC
TTCAGAACAAAGGATCGATT

Downstream 100 bases:

>100_bases
TCGTTTTTTATTAACCGGCTCTAGGGCTAAAACTTAACTTCTATTGGAGAAAATTATGGAAACTGTAATTACAGCAACAA
TCATCGGTGCATCAATTCTT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFH
GPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
QAFIFMMLTVVYLSIAYNKADH

Sequences:

>Translated_262_residues
MSGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFH
GPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVK
EYTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
QAFIFMMLTVVYLSIAYNKADH
>Mature_261_residues
SGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKMQCLVEIVVEWVNGIVKENFHG
PRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGIHYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVKE
YTLHPFNHWAFIPVNFILETVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITLQ
AFIFMMLTVVYLSIAYNKADH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=272, Percent_Identity=53.6764705882353, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_HAEI8 (Q4QN58)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248199.1
- ProteinModelPortal:   Q4QN58
- SMR:   Q4QN58
- STRING:   Q4QN58
- GeneID:   3429926
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0615
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   AGELVFM
- PhylomeDB:   Q4QN58
- ProtClustDB:   PRK05815
- BioCyc:   HINF281310:NTHI0615-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 29333; Mature: 29202

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc5e37e8)-; HASH(0xc6cd49c)-; HASH(0xc438638)-; HASH(0xbc64aac)-; HASH(0xc2f7f20)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
SGQTTSEYISHHLSFLKTGDGFWNVHIDTLFFSILAAVIFLFVFSRVGKKATTGVPGKM
CCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
QCLVEIVVEWVNGIVKENFHGPRNVVAPLALTIFCWVFIMNAIDLIPVDFLPQFAGLFGI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HYLRAVPTADISATLGMSICVFFLILFYTIKSKGFKGLVKEYTLHPFNHWAFIPVNFILE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHH
TVTLLAKPISLAFRLFGNMYAGELIFILIAVMYSANMAIAALGIPLHLAWAIFHILVITL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
QAFIFMMLTVVYLSIAYNKADH
HHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA