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The map label for this gene is yggW [C]

Identifier: 16272411

GI number: 16272411

Start: 485219

End: 486370

Strand: Direct

Name: yggW [C]

Synonym: HI0463

Alternate gene names: 16272411

Gene position: 485219-486370 (Clockwise)

Preceding gene: 16272410

Following gene: 16272412

Centisome position: 26.51

GC content: 38.19

Gene sequence:

>1152_bases
ATGCCAAAACTTCCTCCACTTTCCCTTTATATACACATTCCATGGTGCGTTCAAAAATGCCCTTATTGTGATTTTAATTC
GCACGCACAAAAAAGCGATATACCAGAACAAGACTATATTTATCATCTTCTGCAAGATTTGCAGGCTGATTTGCAACGCT
TTAAAGATTCTATTCAACAACGAAAACTCCATTCAATTTTTATTGGTGGCGGTACACCAAGTTTGTTCTCGGCAGAAAGC
ATTGCGTATCTCTTAAAAGAAATAAAAAAACAGATTGATTTTGAAGATAATATTGAAATCACATTAGAAGCTAATCCTGG
CACGGTAGAAGCTGAACGTTTTAAAGGTTATGTATCCGCAGGCATTATGCGAATTTCTATGGGAATTCAAAGTTTCAATG
ATGATAAATTACAACGTCTTGGGCGGATTCATAATGCAGCAGAAGCAAAAAGTGCGGTCAATTTAGCGAAAGTTTCTGGG
CTAAAAAGTTTTAATTTGGATTTAATGCACGGTTTGCCTAACCAAACGTTGGAAGAAGCCTTAGATGATCTTCGTCAAGC
AATTGAGCTATCTCCTCCCCATATTTCTTGGTATCAGCTGACTATTGAACCAAATACGATGTTTGCTTATCGCCCACCTA
AATTACCAGATGATGACGCACTTTGGGACATTTTTGAGCAAGGTCACCAACTTTTAACGATGGCAGGCTACCAGCAATAT
GAAACCTCAGCTTACGCAAAAGCAGGTTTTCAATGTAAACATAATTTGAATTATTGGCGATTTGGGGATTATTTAGCCAT
TGGCTGTGGCGCACACGGGAAATTGACGTTTCCGACTGGCGAGATTACTCGCTTTTCTAAAACCAAGCACCCGAAAGGTT
ATTTGCGTGGCGAATATCTTTACGAAGAAAAAAACGTGCCAAAAATTGACCGCCCTTTTGAGTTTTTTATGAATCGCTTT
CGTTTGTTAGAAGCGGTACCCAAACAAGAATTTGAAGATTACACAGGCTTGTCGCAAAGTGCGGTGAAAAATCAAATTGA
TTTTGCCATTCAACAAAACTATATTGTGGAAAACGCTGATTCTTGGCAAATCACTGAACACGGCAAGTTATTTCTCAATG
AACTTTTGGAATTATTTTTAACGGAAGAATAG

Upstream 100 bases:

>100_bases
CTTGTGAAAACAAGCCTTTTATTGATTTTAGAGATGATAATTTCATCTTTACACAAGGTTAATTTATACTTTTCCAAATT
GAAAACTTGTTAATAACACA

Downstream 100 bases:

>100_bases
CCTAATCGTGAAATAACCTAGTCGTGAAATAACATTGCTTGAGAAAAACGCCTGTTAAAAATTACACTTGTTTATTAAAT
ACTCTCGTAATAAAGTAACA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAES
IAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGIMRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSG
LKSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
ETSAYAKAGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRF
RLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE

Sequences:

>Translated_383_residues
MPKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAES
IAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGIMRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSG
LKSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
ETSAYAKAGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRF
RLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE
>Mature_382_residues
PKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQRKLHSIFIGGGTPSLFSAESI
AYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSAGIMRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSGL
KSFNLDLMHGLPNQTLEEALDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQYE
TSAYAKAGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYLYEEKNVPKIDRPFEFFMNRFR
LLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENADSWQITEHGKLFLNELLELFLTEE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family

Homologues:

Organism=Homo sapiens, GI8922911, Length=277, Percent_Identity=33.2129963898917, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=66.7539267015707, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI87082341, Length=236, Percent_Identity=30.0847457627119, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y463_HAEIN (P43899)

Other databases:

- EMBL:   L42023
- PIR:   B64070
- RefSeq:   NP_438624.1
- ProteinModelPortal:   P43899
- SMR:   P43899
- GeneID:   949551
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0463
- NMPDR:   fig|71421.1.peg.437
- TIGR:   HI_0463
- HOGENOM:   HBG529648
- OMA:   RKLHSIF
- ProtClustDB:   PRK05660
- BioCyc:   HINF71421:HI_0463-MONOMER
- GO:   GO:0005737
- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197
- SMART:   SM00729
- TIGRFAMs:   TIGR00539

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM

EC number: 1.3.3.3

Molecular weight: Translated: 44106; Mature: 43974

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: BINDING 10-10 BINDING 22-22 BINDING 70-70 BINDING 103-103 BINDING 130-130 BINDING 142-142 BINDING 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLHSIFIGGGTPSLFSAESIAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSA
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
GIMRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSGLKSFNLDLMHGLPNQTLEEA
HHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
LDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
HHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHEEHHHCCHHH
ETSAYAKAGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYL
HHHHHHHCCCCEECCCCEEEECCEEEEECCCCCEEECCCCCCHHCCCCCCCCCCCCCCEE
YEEKNVPKIDRPFEFFMNRFRLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENAD
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCC
SWQITEHGKLFLNELLELFLTEE
CCEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKLPPLSLYIHIPWCVQKCPYCDFNSHAQKSDIPEQDYIYHLLQDLQADLQRFKDSIQQ
CCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKLHSIFIGGGTPSLFSAESIAYLLKEIKKQIDFEDNIEITLEANPGTVEAERFKGYVSA
HHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHH
GIMRISMGIQSFNDDKLQRLGRIHNAAEAKSAVNLAKVSGLKSFNLDLMHGLPNQTLEEA
HHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHH
LDDLRQAIELSPPHISWYQLTIEPNTMFAYRPPKLPDDDALWDIFEQGHQLLTMAGYQQY
HHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHCCHHEEHHHCCHHH
ETSAYAKAGFQCKHNLNYWRFGDYLAIGCGAHGKLTFPTGEITRFSKTKHPKGYLRGEYL
HHHHHHHCCCCEECCCCEEEECCEEEEECCCCCEEECCCCCCHHCCCCCCCCCCCCCCEE
YEEKNVPKIDRPFEFFMNRFRLLEAVPKQEFEDYTGLSQSAVKNQIDFAIQQNYIVENAD
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCC
SWQITEHGKLFLNELLELFLTEE
CCEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800