Click here to switch to the map view.

The map label for this gene is ycfH [C]

Identifier: 16272402

GI number: 16272402

Start: 475521

End: 476303

Strand: Reverse

Name: ycfH [C]

Synonym: HI0454

Alternate gene names: 16272402

Gene position: 476303-475521 (Counterclockwise)

Preceding gene: 16272403

Following gene: 16272401

Centisome position: 26.03

GC content: 40.92

Gene sequence:

>783_bases
ATGTTCATTGTTGACTCCCACTGCCATTTAGATGCGTTGGATTATGAAAATTTACATAAAAATATCTCGGATGTGGTGGA
AAAAGCGCACGCACGTGATGTGAAACATTTGCTCGCGATTGGTGTAACCTTAAGCCGTTTTGAGCAGGCTTATGACTCTT
TACGGGAATTTAATAATGTCTCGCTTGCTTGTGGTGTTCACCCACTTGATTTTGAAGAAGAACCTTATGACGCAGAACGT
TTATTGCGTTTAGCGCAAGATCCTAAAGTGATTGCTATTGGCGAAATTGGCTTAGATTATTATTACAGTGCGGACAATAA
AGCGGCGCAACAAGCGGTGTTTGGTAGCCAAATCGATATTGCAAACCAATTAGATAAGCCTGTGATTATTCATACACGTT
CTGCAGGCGATGACACCATTGCAATGTTACGCCAACACCGTGCTGAAAAGTGCGGTGGCGTTATTCATTGTTTTACGGAA
ACTATGGAATTTSCGAAAAAAGCGTTGGATTTAGGATTTTACATTTCTTGTTCTGGCATTGTCACCTTTAAAAATGCTGA
AGCGATTCGTGAGGTTATTCGTTATGTACCAATGGAACGCTTATTGGTGGAAACGGATTCGCCTTATCTTGCGCCAGTGC
CTTACAGAGGAAAAGAAAATCAACCAGCGTATACGAGAGAAGTATGTGAATACGTGGCAACCTTAAAGGGCGTTTCTGCA
GAGGCGTTTGCTCAAATCACTACACAAAATTTCGAGCGTTTATTTAAAATTCGTGTAGAATAA

Upstream 100 bases:

>100_bases
GGATGGCTTGACACGATTAGTCACAGAAGTATTTGAAACGCAATAAATTAAAGATATATCGTCTATGGCGTTCAAGCCTT
AGGCATAAGGAAAAATAATT

Downstream 100 bases:

>100_bases
ATGCACAGTTCTAACAAGGGAAAAGTATGCGAAAGTTTTTTAAATATTTCTTATTTATTGTTGTTTTTTTATTCCACGGT
TTTATGTTTTCCGTAGTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNVSLACGVHPLDFEEEPYDAER
LLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDIANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTE
TMEFXKKALDLGFYISCSGIVTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSA
EAFAQITTQNFERLFKIRVE

Sequences:

>Translated_260_residues
MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNVSLACGVHPLDFEEEPYDAER
LLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDIANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTE
TMEFXKKALDLGFYISCSGIVTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSA
EAFAQITTQNFERLFKIRVE
>Mature_260_residues
MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNVSLACGVHPLDFEEEPYDAER
LLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDIANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTE
TMEFXKKALDLGFYISCSGIVTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSA
EAFAQITTQNFERLFKIRVE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family

Homologues:

Organism=Homo sapiens, GI110349730, Length=273, Percent_Identity=30.7692307692308, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI110349734, Length=273, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI226061853, Length=279, Percent_Identity=30.1075268817204, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI226061614, Length=262, Percent_Identity=30.5343511450382, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI225903424, Length=219, Percent_Identity=27.3972602739726, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI226061595, Length=232, Percent_Identity=28.8793103448276, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI14042943, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI225903439, Length=155, Percent_Identity=32.9032258064516, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=59.9221789883268, Blast_Score=321, Evalue=3e-89,
Organism=Escherichia coli, GI48994985, Length=251, Percent_Identity=32.6693227091633, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=26.3565891472868, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=273, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.0566037735849, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17565396, Length=311, Percent_Identity=23.7942122186495, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24648690, Length=219, Percent_Identity=30.5936073059361, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=28.7822878228782, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=28.7822878228782, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y454_HAEIN (P44718)

Other databases:

- EMBL:   L42023
- PIR:   I64152
- RefSeq:   NP_438615.1
- ProteinModelPortal:   P44718
- GeneID:   949545
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0454
- NMPDR:   fig|71421.1.peg.428
- TIGR:   HI_0454
- HOGENOM:   HBG629833
- OMA:   TREVCEY
- ProtClustDB:   CLSK870567
- BioCyc:   HINF71421:HI_0454-MONOMER
- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991
- PANTHER:   PTHR10060
- PIRSF:   PIRSF005902
- TIGRFAMs:   TIGR00010

Pfam domain/function: PF01026 TatD_DNase

EC number: 3.1.21.-

Molecular weight: Translated: 29365; Mature: 29365

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS01137 TATD_1; PS01090 TATD_2; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLACGVHPLDFEEEPYDAERLLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDI
EEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCCHHHHHHHCCCCCCH
ANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTETMEFXKKALDLGFYISCSGI
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCE
VTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSA
EEECCHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
EAFAQITTQNFERLFKIRVE
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIVDSHCHLDALDYENLHKNISDVVEKAHARDVKHLLAIGVTLSRFEQAYDSLREFNNV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLACGVHPLDFEEEPYDAERLLRLAQDPKVIAIGEIGLDYYYSADNKAAQQAVFGSQIDI
EEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCCHHHHHHHCCCCCCH
ANQLDKPVIIHTRSAGDDTIAMLRQHRAEKCGGVIHCFTETMEFXKKALDLGFYISCSGI
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCE
VTFKNAEAIREVIRYVPMERLLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSA
EEECCHHHHHHHHHHCCHHHHEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
EAFAQITTQNFERLFKIRVE
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800