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The map label for this gene is ytfL [C]

Identifier: 16272400

GI number: 16272400

Start: 473621

End: 474919

Strand: Reverse

Name: ytfL [C]

Synonym: HI0452

Alternate gene names: 16272400

Gene position: 474919-473621 (Counterclockwise)

Preceding gene: 16272401

Following gene: 16272399

Centisome position: 25.95

GC content: 37.64

Gene sequence:

>1299_bases
ATGATTATGGAATTATTTCATACTATTTTGGCAATTGTGGCTTTAATTTTAAGTAGCGCAGTTGTTTCTTCTGCTGAAAT
TTCTCTGGCGAGTCCTCGTAAGTTAAAATTGCAATCTCTTGCAAATAAAGGCGACGTGCGTCCGCTTCAAGTGCTTAAAT
TACAAGAGCATCCTGGTCGTTTTATTACGGTGGTTCAAATTTTGTTGAATATGGTGGCGATTTTGGGTGGGGGAATTGGC
GAAAGTGCGCTAAGTCCTTACATTGCAGATATTTTAAATCGTTCTTTTGAAGGAAGTTGGATTGCGCCAACCGCCTCTAC
AATCGCTTTTATATTAGTGACTTGTTTGTTTATTTTATTTGCTGATCTTATTCCAAAACGAATTGCTATTACTTATCCTG
AAATGGTGGCGTTGAGCGTTGTGGGTATTATGAATTTTAGTATGTATGTGTTTAAACCGCTTGTGTGGTTTTTTGATACT
ATTGCTAATGTATTTTTCCGCTTATTTCGCATTTCTACTGTGCGTGAAGATGGCATGACCTCTGAAGATATTTTCGCCGT
AGTTGAAGCAGGCGCAGAAGCTGGTGTATTAAAAACTCAAGAGCATTATTTGATCGAAAATATTTTCGATATGCAAGCCC
GTACGGTAACTTCCACAATGACAACCCGTGAAAACATCGTATATTTAGACCGCACTTTTTCTCGCCAAGAAGTCATGGAT
ACGCTTTCTCGTGATTCTCATTCTAAAATTGTGATTTGTGACAATGGCCTCGACAAAATCTTAGGTTATATCGAATCCCA
TACTTTGCTCACAATGTATTTGCAGAATGAAAATGTGGTGCTGACTGATCCCAAACTACTACGTAAAGCCTTATTTGTGC
CTGATACGCTTTCTCTTTACGAAGTGTTGGAATTGTTTAAATCTACTGGCGAAGATTTTGCGATTATTGTGAATGAATAT
GCTCTTGTAGTGGGTATTGTTACGCTAAATGATGTGATGAGTATTGTTATGGGGGAATTGGTTTCTAACGAAGAAGAATA
TATTGTGAGCCGTGATGAAAACTCGTGGCTGATTGATGGCGCAACGCCATTAGAAGAGGTAACTCGAGTATTAGATATTG
CTTATTTTCCCGATGAAGAAAACTACGAAACTATCAGTGGTTTTATGATGTATATGTTACGTAAAATCCCGAAAAAAACC
GATTCTGTGGTTTACGGAAAATACAAGTTTGAAGTGATTGATACGGAAAACTTTAAAATCGATCAGATTTTGGTGTCTTT
AGTAAAAGAGCAGGAGTAG

Upstream 100 bases:

>100_bases
TATTTTTGTCTATCCAATTTATTCGCGGCTGGTTTGACAGCGATAAGTAATATCCCAAACGGTCGCAAAGTGCGGTCGTT
TTCTTTTATATTTTTGAGTA

Downstream 100 bases:

>100_bases
AAGTGCGGTAAATTTTTATCCATTTCTCTACAAAATTATGTTATAAAACCATAAAAAATTTGAGGTTAAATATGGAACTA
AGACAACAAATTCCAACAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIMELFHTILAIVALILSSAVVSSAEISLASPRKLKLQSLANKGDVRPLQVLKLQEHPGRFITVVQILLNMVAILGGGIG
ESALSPYIADILNRSFEGSWIAPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALSVVGIMNFSMYVFKPLVWFFDT
IANVFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMD
TLSRDSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEY
ALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKT
DSVVYGKYKFEVIDTENFKIDQILVSLVKEQE

Sequences:

>Translated_432_residues
MIMELFHTILAIVALILSSAVVSSAEISLASPRKLKLQSLANKGDVRPLQVLKLQEHPGRFITVVQILLNMVAILGGGIG
ESALSPYIADILNRSFEGSWIAPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALSVVGIMNFSMYVFKPLVWFFDT
IANVFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMD
TLSRDSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEY
ALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKT
DSVVYGKYKFEVIDTENFKIDQILVSLVKEQE
>Mature_432_residues
MIMELFHTILAIVALILSSAVVSSAEISLASPRKLKLQSLANKGDVRPLQVLKLQEHPGRFITVVQILLNMVAILGGGIG
ESALSPYIADILNRSFEGSWIAPTASTIAFILVTCLFILFADLIPKRIAITYPEMVALSVVGIMNFSMYVFKPLVWFFDT
IANVFFRLFRISTVREDGMTSEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMD
TLSRDSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLYEVLELFKSTGEDFAIIVNEY
ALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDGATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKT
DSVVYGKYKFEVIDTENFKIDQILVSLVKEQE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=23.2804232804233, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=52.5700934579439, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=25.0596658711217, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=30.2919708029197, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=27.4261603375527, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786879, Length=277, Percent_Identity=22.7436823104693, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y452_HAEIN (P44717)

Other databases:

- EMBL:   L42023
- PIR:   H64152
- RefSeq:   NP_438613.1
- ProteinModelPortal:   P44717
- SMR:   P44717
- GeneID:   949660
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0452
- NMPDR:   fig|71421.1.peg.426
- TIGR:   HI_0452
- HOGENOM:   HBG673071
- OMA:   ENSWLVE
- ProtClustDB:   CLSK870569
- BioCyc:   HINF71421:HI_0452-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 48708; Mature: 48708

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc124468)-; HASH(0xc86e0f8)-; HASH(0xce362f4)-; HASH(0xc4b19f8)-; HASH(0xc4279d8)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMELFHTILAIVALILSSAVVSSAEISLASPRKLKLQSLANKGDVRPLQVLKLQEHPGR
CHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHCCCCCCCHHHHEEECCCCCH
FITVVQILLNMVAILGGGIGESALSPYIADILNRSFEGSWIAPTASTIAFILVTCLFILF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHH
ADLIPKRIAITYPEMVALSVVGIMNFSMYVFKPLVWFFDTIANVFFRLFRISTVREDGMT
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMD
HHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
TLSRDSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLY
HHCCCCCCEEEEECCCHHHHHHHHHCCEEEEEEEECCCEEEECHHHHHHHHCCCCHHHHH
EVLELFKSTGEDFAIIVNEYALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDG
HHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEC
ATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDSVVYGKYKFEVIDTENFKI
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCH
DQILVSLVKEQE
HHHHHHHHHCCH
>Mature Secondary Structure
MIMELFHTILAIVALILSSAVVSSAEISLASPRKLKLQSLANKGDVRPLQVLKLQEHPGR
CHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHCCCCCCCHHHHEEECCCCCH
FITVVQILLNMVAILGGGIGESALSPYIADILNRSFEGSWIAPTASTIAFILVTCLFILF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHH
ADLIPKRIAITYPEMVALSVVGIMNFSMYVFKPLVWFFDTIANVFFRLFRISTVREDGMT
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SEDIFAVVEAGAEAGVLKTQEHYLIENIFDMQARTVTSTMTTRENIVYLDRTFSRQEVMD
HHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
TLSRDSHSKIVICDNGLDKILGYIESHTLLTMYLQNENVVLTDPKLLRKALFVPDTLSLY
HHCCCCCCEEEEECCCHHHHHHHHHCCEEEEEEEECCCEEEECHHHHHHHHCCCCHHHHH
EVLELFKSTGEDFAIIVNEYALVVGIVTLNDVMSIVMGELVSNEEEYIVSRDENSWLIDG
HHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEC
ATPLEEVTRVLDIAYFPDEENYETISGFMMYMLRKIPKKTDSVVYGKYKFEVIDTENFKI
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCH
DQILVSLVKEQE
HHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800