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The map label for this gene is yhjE [C]

Identifier: 16272367

GI number: 16272367

Start: 439995

End: 441338

Strand: Direct

Name: yhjE [C]

Synonym: HI0418

Alternate gene names: 16272367

Gene position: 439995-441338 (Clockwise)

Preceding gene: 16272366

Following gene: 16272368

Centisome position: 24.04

GC content: 44.35

Gene sequence:

>1344_bases
ATGTGCAAGCCGCAACAAAAGCATTACGGGAGGCAAGTGATGAATACGCAAAATAGTTTAAAGCAAGTAGCAACAGCGAC
GATGGTCGGCACTGCAATTGAGTATTTCGATAACTACATTTACGCAATGGCAGCGGTATTGGTATTTAACCATCAATTCT
TCCATGCCGTAGATCCACTTTCAGGGCAGATTGCGGCACTTTCCACTTTAGCACTTACTTTTATTGCTCGCCCTTTGGGA
GCAATATTGTTCGGGCATTTCGGTGACCGTTTCGGGCGGAAAAATACTTTTGTGATGAGCTTGCTGTTGATGGGTATTTC
CACTGTGGTTATCGGTTTGTTGCCAACCTATGACAGCATCGGTATTTGGGCGACAATTTTGCTCTGTTTATGCCGTATTG
GGCAAGGTATCGGTTTAGGCGGAGAGTGGGGCGGTGCAGCGTTAGTTGCGGTTGAAAATGCTCCAGAAGGTAAACGAGGT
TGGTATGGTACTTTCCCTCAACTGGGAGCCCCGCTTGGCTTGTTGTTGGCAAATGGCGTATTCTTAGGCATTACTGCGAT
TTTCGGGCAAGAAGCTATGACTGAATGGGCGTGGCGGATACCGTTTTTATCTTCCGTTATCTTAGTAGCAATTGGCTTAT
ATGTTCGCCTAAAACTGACTGAAGCCCCGATTTTCCTCGCGGCACTTAACAAGCCAAAACCTAAACGCTTACCAATGTTG
GAAGTTGTCACTACTCATTTTAAGCCGTTTTTCTTAGGAATGTTGGTTTGCATTGCTGGCTATGTGCTGTTCTACATTAT
GATTGCCTTTAGCCAAATTTACGCCAAATCTGCTCCAACGGTTTCAGAGGCAGGATACGCAATGGGATTAGGATTTTCCC
CGCAAATTTTTACCGCTTTATTGATGGCAAGTGCGGTTTCTTTGGCAATAACGATTGCCGCTTCGGGTAAATATATCGAC
AAAATTGGACGAAGAACTTGGTTAATTTGGACAACTGTTGGAGTTGCGATTTTTGGTTTATCCTTGCCGTTATTTCTCGA
AAACGGTACAACTACCAGTCTGTTTTGGTTTTTATTCATCGGTATGGGGTTAATTGGAATGGGCTATGGGCCATTAGCGA
GTTTTTTACCTGAACTCTTCCCTACTCACGCCCGCTATTCAGGTGCGTCACTCACTTACAACATCGCAGGCTTATTCGGG
GCAAGTGTTGCGGCAATCATTGCCTTACCACTGAATGCTCACTACGGCTTAAAAGGTGTGGGGATTTATTTAACCCTAAA
CGCTGTGTTGAGCTTGGTTGGATTATGGTTTATTTCAGAAACGAAAGATAAATTACTATCCTAA

Upstream 100 bases:

>100_bases
CTTGTGGCAATTGGTGGGGTGAAATTAGCTCACGTTAAAACCTTACGAGAATTTGGGGCGGATGGTGTGGCAGTGATTAC
TGCAATTACGCACGCCGATA

Downstream 100 bases:

>100_bases
GATTTGAGGAATTAAATACAACCTATTAAGCGGTTAAATTTTATATAAAATTCCACTAAGAATTTAACCGCACTTTCCTT
TACAAGCCAAATATTTTCTC

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPLSGQIAALSTLALTFIARPLG
AILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSIGIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRG
WYGTFPQLGAPLGLLLANGVFLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPML
EVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTALLMASAVSLAITIAASGKYID
KIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFIGMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFG
ASVAAIIALPLNAHYGLKGVGIYLTLNAVLSLVGLWFISETKDKLLS

Sequences:

>Translated_447_residues
MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPLSGQIAALSTLALTFIARPLG
AILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSIGIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRG
WYGTFPQLGAPLGLLLANGVFLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPML
EVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTALLMASAVSLAITIAASGKYID
KIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFIGMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFG
ASVAAIIALPLNAHYGLKGVGIYLTLNAVLSLVGLWFISETKDKLLS
>Mature_447_residues
MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPLSGQIAALSTLALTFIARPLG
AILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSIGIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRG
WYGTFPQLGAPLGLLLANGVFLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPML
EVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTALLMASAVSLAITIAASGKYID
KIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFIGMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFG
ASVAAIIALPLNAHYGLKGVGIYLTLNAVLSLVGLWFISETKDKLLS

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Escherichia coli, GI1789941, Length=437, Percent_Identity=45.9954233409611, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1788292, Length=420, Percent_Identity=33.0952380952381, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1790550, Length=443, Percent_Identity=30.6997742663657, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1788942, Length=412, Percent_Identity=29.3689320388349, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI87082231, Length=420, Percent_Identity=22.3809523809524, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082404, Length=364, Percent_Identity=23.0769230769231, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y418_HAEIN (P44699)

Other databases:

- EMBL:   L42023
- PIR:   B64152
- RefSeq:   NP_438580.1
- ProteinModelPortal:   P44699
- GeneID:   950811
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0418
- NMPDR:   fig|71421.1.peg.393
- TIGR:   HI_0418
- HOGENOM:   HBG757988
- OMA:   PTHARYS
- ProtClustDB:   CLSK789715
- BioCyc:   HINF71421:HI_0418-MONOMER
- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829
- TIGRFAMs:   TIGR00883

Pfam domain/function: PF00083 Sugar_tr; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 48230; Mature: 48230

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbc9bf8c)-; HASH(0xcd5a5ec)-; HASH(0xcd5a6a0)-; HASH(0xbe5a8e4)-; HASH(0xbbd1128)-; HASH(0xc7b34ec)-; HASH(0xaf79b94)-; HASH(0xc8fb4e0)-; HASH(0xc0f02c4)-; HASH(0xb00d89c)-; HASH(0xbfe2aac)-; HASH(0xc390e18)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGQIAALSTLALTFIARPLGAILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
GIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRGWYGTFPQLGAPLGLLLANGV
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHCCH
FLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHH
EVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEECCCCCHHHHHHH
LMASAVSLAITIAASGKYIDKIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFI
HHHHHHHHEEEEECCCHHHHHHCCEEEEEHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
GMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFGASVAAIIALPLNAHYGLKGV
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEECCCCCCCCCE
GIYLTLNAVLSLVGLWFISETKDKLLS
EHEEEHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGQIAALSTLALTFIARPLGAILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
GIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRGWYGTFPQLGAPLGLLLANGV
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHCCH
FLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCHH
EVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEECCCCCHHHHHHH
LMASAVSLAITIAASGKYIDKIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFI
HHHHHHHHEEEEECCCHHHHHHCCEEEEEHHHHHHHHHHCCCCEEEECCCHHHHHHHHHH
GMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFGASVAAIIALPLNAHYGLKGV
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEECCCCCCCCCE
GIYLTLNAVLSLVGLWFISETKDKLLS
EHEEEHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800