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The map label for this gene is xseA [H]

Identifier: 16272346

GI number: 16272346

Start: 418569

End: 419888

Strand: Direct

Name: xseA [H]

Synonym: HI0397

Alternate gene names: 16272346

Gene position: 418569-419888 (Clockwise)

Preceding gene: 16272345

Following gene: 30995372

Centisome position: 22.87

GC content: 41.82

Gene sequence:

>1320_bases
ATGTCAGACAATATTTATTCCGTCTCTCAACTGAATTCTGCCGCGCGTCAGATGCTTGAGGGTAATTTTTGCCAAATTTG
GCTAACGGGGGAAATTTCCAATTTTACCCAACCTGTGTCTGGACATTGGTATTTAACGCTGAAAGATGAAAATGCACAGG
TGCGTTGTGCAATGTTTCGTATGAAAAATTTGCGTGTAGCTTTTCGTCCACAAAATGGAATGCAAGTGCTTGTGCGTGCC
AATGTGAGTTTATATGAGCCTCGCGGCGATTATCAGCTTATTATTGATTCTATGCACCCAGCAGGCGAGGGATTATTGCA
ACAGCAATTTGAAGCGTTAAAAATGAAGTTGGCTGCGGAAGGATTGTTTGCTCAAAATCTTAAGAAAACTCTACCGCACT
TTAGTAAAGCAGTGGGGATTATAACTTCTTCTACAGGTGCGGCATTGCAAGATATTTTGCATATTCTGGCACGCCGTGAT
CCAAGTTTAAAAGTCGTCATTTATCCCACTGCGGTTCAAGGCAAAGAGGCAACTGCAGAAATTGTGCAAATGATTGAACT
TGCTAATGCGCGACAAGAAGTAGATGTATTAATTGTGGGGCGTGGTGGTGGTTCATTAGAAGATCTTTGGTGTTTTAATG
AAGAAGAAGTGGCGCGAGCGATTTTTCGTTCAACCTTACCTATTATCAGTGCGGTGGGACACGAAACAGATGTGACGATT
GCCGATTTCGTTGCAGATCTTCGTGCGCCAACCCCCTCTGCTGCGGCTGAGTTAGTTAGTCGTAATCAAGATGAATTATT
GCAACAACTTCGCCATCAACAGCAACGTTTAGATATGGCATTTGATCGTTTATTTACGCGAAAAAGCCAGCGTTTGAAAC
AGCTTGCCTTACGATTGCAAAATCAACATCCACAGAATCAGCTACGTGCTCAACAAGCGAAAAATGAACAGCTTACACAT
CGCTTGCAACTTGCAATATTGCGTCAGTTTGAAAATACACAACAAAAATTCACCGCACTTTCTGTTCGTTTAAAACAAAA
TCCATTGCCATATCGCATACAACGTTATCAACAAGGCTTAGAGCAGTTAAAAGTGCGGTTAAATTTTTGCGTAAATCGCC
AAGTGACGGAACGTCAAAATAAACTGGCAACATTATGCGGAAAACTGGATGGCTTAAGCCCATTAAAAGTCTTGGCGAGA
GGTTATTCCATTGCGGAAAATCCGCAAGGTAAAGCCATTGTTAGCGTGAAAGATGTCAATCAAGGGGACTTCATTACAAC
TCAAGTGGCTGATGGAAAAATTGTGAGTAAGGTTTTGTAA

Upstream 100 bases:

>100_bases
GATTTAGCCAATAAAACAGAAGATCCTGAAACCTCAATGGATTTGTTGTTGGATTCCATTTGTAACTGGGTTGATGATGG
GTGGGCGTTAATTGAATAAT

Downstream 100 bases:

>100_bases
GATGCTTATTTTGTAAAAATGGAGTGAAATACTGTTTCACTTACTTCTAAAAAAGAATGCTATGACTGTTGAATAAATAA
TCATGGCATTTTGTTTTTTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSDNIYSVSQLNSAARQMLEGNFCQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVLVRA
NVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAEGLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRD
PSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTI
ADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQNQHPQNQLRAQQAKNEQLTH
RLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGLEQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLAR
GYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL

Sequences:

>Translated_439_residues
MSDNIYSVSQLNSAARQMLEGNFCQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVLVRA
NVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAEGLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRD
PSLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTI
ADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQNQHPQNQLRAQQAKNEQLTH
RLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGLEQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLAR
GYSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL
>Mature_438_residues
SDNIYSVSQLNSAARQMLEGNFCQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFRMKNLRVAFRPQNGMQVLVRAN
VSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAEGLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRDP
SLKVVIYPTAVQGKEATAEIVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTIA
DFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQNQHPQNQLRAQQAKNEQLTHR
LQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGLEQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARG
YSIAENPQGKAIVSVKDVNQGDFITTQVADGKIVSKVL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=438, Percent_Identity=57.9908675799087, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49434; Mature: 49302

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNIYSVSQLNSAARQMLEGNFCQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFR
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEHHEEH
MKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAE
HHCCEEEEECCCCCEEEEEECCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRDPSLKVVIYPTAVQGKEATAE
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
IVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTI
HHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
ADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQ
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQHPQNQLRAQQAKNEQLTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHH
EQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARGYSIAENPQGKAIVSVKDVN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECC
QGDFITTQVADGKIVSKVL
CCCEEEEEECCCHHHHHCC
>Mature Secondary Structure 
SDNIYSVSQLNSAARQMLEGNFCQIWLTGEISNFTQPVSGHWYLTLKDENAQVRCAMFR
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEHHEEH
MKNLRVAFRPQNGMQVLVRANVSLYEPRGDYQLIIDSMHPAGEGLLQQQFEALKMKLAAE
HHCCEEEEECCCCCEEEEEECCEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GLFAQNLKKTLPHFSKAVGIITSSTGAALQDILHILARRDPSLKVVIYPTAVQGKEATAE
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
IVQMIELANARQEVDVLIVGRGGGSLEDLWCFNEEEVARAIFRSTLPIISAVGHETDVTI
HHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
ADFVADLRAPTPSAAAELVSRNQDELLQQLRHQQQRLDMAFDRLFTRKSQRLKQLALRLQ
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQHPQNQLRAQQAKNEQLTHRLQLAILRQFENTQQKFTALSVRLKQNPLPYRIQRYQQGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHH
EQLKVRLNFCVNRQVTERQNKLATLCGKLDGLSPLKVLARGYSIAENPQGKAIVSVKDVN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECC
QGDFITTQVADGKIVSKVL
CCCEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA