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The map label for this gene is pbpG

Identifier: 16272312

GI number: 16272312

Start: 387648

End: 388526

Strand: Reverse

Name: pbpG

Synonym: HI0364

Alternate gene names: 16272312

Gene position: 388526-387648 (Counterclockwise)

Preceding gene: 16272319

Following gene: 16272311

Centisome position: 21.23

GC content: 34.24

Gene sequence:

>879_bases
ATGTTTAAAAAAGCTTTATTTATTTTATCTTTGTGTCCTTCTTTTGCGTTGGCACAGTCTTATGTTGTGTATGATTTTAC
CCATAATCGAGTGTTGGAAAGCCACGCGTCTGATAGTATTCAGCCTATTGCCTCTGTAACAAAATTAATGACGGCTAATG
TATTTTTAGAGAATAATAAAAATCCTAATTGTCGAATCGCAATCACAAAAGAGGATACGGATCGAATTAAAGGCACTGGA
ACAAAATTACCTAAAAATATTCCTATTTCTTGTAACGAATTATTGAAAGCAATGCTTGTCCATTCTGATAACTATGCCGC
CCACGCGCTTTCTCGTGCAGCGGGAATAAGTCGTCGCCAATTTATTAAGAAAATGAACGAAAAAGCCCATCAACTTGGTA
TGTATTCTACTCGTTTTCACGATAGTTCAGGATTATCTAGCTATAATATTTCCAGCCCAATGGATTTAGTTAAGCTCGCC
AAATATTCATTAAATAAATCGGACATTAAACGTTTATCTAATCTTAGTGCAACTTATATCCAAGCAGGGAAACAAAAACT
TTATATTAAAAATACCAATAAGTTAGTGCGTGATGAAATTTTTGATGCGGCAGTGAATAAAACAGGCTACATTCAAGAAT
CTGGTTATAATCTCGTTTTCATTAATAAACACCGATGCAAAAATGCAACTATTGGCGTAATTAGTTTAAATAACACTTCC
TCAGCGTATCGTTCTAGTTTTACTAAAAGCAAATTAGAAAAATTCGGCTGCACGGCATTAAATGGAAGAACAATTCGTGA
TGTAGCAGGAGAAGCCCAATATGAAGATGGCTATGATGAAGTGGGATTTAATACGCTAATTCAGAAATTATCAAAATAA

Upstream 100 bases:

>100_bases
AAATCTTACCGCACTTTTTTGCGATCTAGATCGCAAATATTTTCAATTACAGCGGAAAAAGTGCGGTAAAATATCAGCCT
ATTTTTTAAGGTGACCAATA

Downstream 100 bases:

>100_bases
TGTTCATAAACATAAAAATGCGAGATAACAGTTTGTTTTATCTCGCATTTTTTAGCTGATGAGCAGGCTGTTCTACAGTG
ACTTTTTCTTGGTCAGTTGT

Product: penicillin-binding protein 7

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7 homolog; PBP-7

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNKNPNCRIAITKEDTDRIKGTG
TKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQFIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLA
KYSLNKSDIKRLSNLSATYIQAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTS
SAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK

Sequences:

>Translated_292_residues
MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNKNPNCRIAITKEDTDRIKGTG
TKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQFIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLA
KYSLNKSDIKRLSNLSATYIQAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTS
SAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK
>Mature_292_residues
MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNKNPNCRIAITKEDTDRIKGTG
TKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQFIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLA
KYSLNKSDIKRLSNLSATYIQAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTS
SAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family

Homologues:

Organism=Escherichia coli, GI87082054, Length=211, Percent_Identity=32.7014218009479, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PBP7_HAEIN (P44664)

Other databases:

- EMBL:   L42023
- PIR:   H64149
- RefSeq:   NP_438525.1
- ProteinModelPortal:   P44664
- SMR:   P44664
- MEROPS:   S11.002
- GeneID:   949374
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0364
- NMPDR:   fig|71421.1.peg.338
- TIGR:   HI_0364
- HOGENOM:   HBG728991
- OMA:   VKLAKYS
- ProtClustDB:   CLSK892366
- BioCyc:   HINF71421:HI_0364-MONOMER
- GO:   GO:0006508
- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967
- PRINTS:   PR00725

Pfam domain/function: PF00768 Peptidase_S11; SSF56601 PBP_transp_fold

EC number: 3.4.99.- [C]

Molecular weight: Translated: 32621; Mature: 32621

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: ACT_SITE 45-45 ACT_SITE 48-48 ACT_SITE 102-102 BINDING 207-207

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNK
CCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCC
NPNCRIAITKEDTDRIKGTGTKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQ
CCCEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
FIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLAKYSLNKSDIKRLSNLSATYI
HHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHH
QAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTS
HCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCEEEEEEECCCC
SAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK
HHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHCCHHHHHHHHCC
>Mature Secondary Structure
MFKKALFILSLCPSFALAQSYVVYDFTHNRVLESHASDSIQPIASVTKLMTANVFLENNK
CCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCC
NPNCRIAITKEDTDRIKGTGTKLPKNIPISCNELLKAMLVHSDNYAAHALSRAAGISRRQ
CCCEEEEEECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
FIKKMNEKAHQLGMYSTRFHDSSGLSSYNISSPMDLVKLAKYSLNKSDIKRLSNLSATYI
HHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHH
QAGKQKLYIKNTNKLVRDEIFDAAVNKTGYIQESGYNLVFINKHRCKNATIGVISLNNTS
HCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCEEEEEEECCCC
SAYRSSFTKSKLEKFGCTALNGRTIRDVAGEAQYEDGYDEVGFNTLIQKLSK
HHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800