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The map label for this gene is ampG [C]

Identifier: 16272301

GI number: 16272301

Start: 376624

End: 377901

Strand: Reverse

Name: ampG [C]

Synonym: HI0350

Alternate gene names: 16272301

Gene position: 377901-376624 (Counterclockwise)

Preceding gene: 16272302

Following gene: 16272300

Centisome position: 20.65

GC content: 38.73

Gene sequence:

>1278_bases
ATGTCAAATTCCCTTTCTTCTCAAATTTTTACGCGCAAGATGTTAATTTGCGCCTTCACAGGTTTTAATTCTGGTTTGCC
ATTATTTGTATTGTCGCAAATGTTGCCTGTTTGGCTGACAGATAAACATCTTTCAATTGAGCTTATTGGTGCAGTAACGG
GTGTGATGTTGCCTTATGGATTGAAATTTTTGTGGGCACCATTATTAGATCGTTATTTCCCGAGTTTTTTAGGGCGTCGT
CGTAGCTGGATGTTGCTTTCACAAGTGGCATTATTGATTTTACTTTACATCATTAGCCTGTTTGATCCGCTCACACAACT
GGGTACAGTAGCAAATATTGCGTTGCTTATCGCCTTTTTTTCAGCTACACAAGATATCGTGTTGGATGCGTATCGTCGTG
AAATTTTGAGTGATCATGAATTAGGTTTAGGAAACACTATTCATATTAATGCTTATCGAATTGCGGGATTAATTCCAGGG
GGATTATCGCTATATTTGGCGGCGATTTATCCTTGGGAAACCGTCTTTTTATGGACCGCACTTTGTATGTTAGCAGGCAT
CTTCATGACACTATTTTTAGCCAAAGAGCCAAAAATAGACATGCAGCAAACTAATCAGCCGTTCTATCAAGCATTTTGGA
TTCCATTACAAGAATTTTTCCAGCGTAAGGGCGTCATTCAGGCTATCGGTTTTTTACTATTTTTGTTTTTGTATAAGTTC
GGGGATTCTTTTGCCACAACGTTACAAACCAAATTTATTTATGACATGGGATTTAGCAAAGAGGATATTGCTATTGTTGT
AAAAAGTACCGCACTTTGGTCAAGCATTTTATCTGGGCTTGCTGGTGGTATGATAATGCTAAAACTGGGTATTAATCGTG
CATTGTGGCTATTTGGGCTTGTACAAATGGTAACAATTGGTGGGTTTATTTGGTTGGCTGCTTTTGGACATTTTGATGTT
ATTACATCTGCCGAGTTATGGAAACTAGGTGTTGTGATTGCAGCAGAATATATCGGCGTTGGACTTGGTACCGCTGCTTT
TGTGGCTTTTATGGCGCGTGAGAGTAATCCTCTTTATACTGCAACACAGCTTGCACTTTTTACAAGCCTTTCAGCTTTGC
CAAGTAAAGTTTTAGGTATACTTTCTGGTTATGTTGTGGGAGCAGTGGGGTATTATCAGTATTTTTGGTTTTGTTTATTT
TTAGCGATTCCCGGCATGCTTTGTTTATTTTGGGTAGCACCTTTGAAGCAAGAAAATAATAAGACCAGCTCAGTATAA

Upstream 100 bases:

>100_bases
CTAAACATTAGGGGAATGATTAAAAATCCCCTAATTTTTACAAAAATCCTTTAATTGAAAGGCGAAATTTCTAAAATACA
ACTAAAATTAACCGCACTTT

Downstream 100 bases:

>100_bases
AAGTGCGGTAAAAATTATAAAAAATTTGACCGCACTATGCTTTATCAGTATCTTAATCACGTTTTGTATTAATGGAGATT
TTTTATGAAAATTATTCTTT

Product: permease

Products: NA

Alternate protein names: ORF3

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRR
RSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPG
GLSLYLAAIYPWETVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKF
GDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDV
ITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLF
LAIPGMLCLFWVAPLKQENNKTSSV

Sequences:

>Translated_425_residues
MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRR
RSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPG
GLSLYLAAIYPWETVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKF
GDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDV
ITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLF
LAIPGMLCLFWVAPLKQENNKTSSV
>Mature_424_residues
SNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYGLKFLWAPLLDRYFPSFLGRRR
SWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFFSATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGG
LSLYLAAIYPWETVFLWTALCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKFG
DSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGLVQMVTIGGFIWLAAFGHFDVI
TSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYTATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFL
AIPGMLCLFWVAPLKQENNKTSSV

Specific function: Probably Acts As A Permease In The Beta-Lactamase Induction System And In Peptidoglycan Recycling. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli AmpG and yeast YBR220c

Homologues:

Organism=Homo sapiens, GI19923957, Length=269, Percent_Identity=26.7657992565056, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI300360496, Length=133, Percent_Identity=35.3383458646617, Blast_Score=65, Evalue=1e-10,
Organism=Homo sapiens, GI4757708, Length=133, Percent_Identity=35.3383458646617, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786636, Length=391, Percent_Identity=37.8516624040921, Blast_Score=235, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71996375, Length=132, Percent_Identity=31.0606060606061, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17536531, Length=132, Percent_Identity=31.0606060606061, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y350_HAEIN (P24326)

Other databases:

- EMBL:   X57315
- EMBL:   L42023
- PIR:   D64149
- RefSeq:   NP_438514.1
- ProteinModelPortal:   P24326
- GeneID:   949456
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0350
- NMPDR:   fig|71421.1.peg.327
- TIGR:   HI_0350
- HOGENOM:   HBG713261
- OMA:   FKWAWSP
- ProtClustDB:   CLSK808406
- BioCyc:   HINF71421:HI_0350-MONOMER
- InterPro:   IPR004752
- InterPro:   IPR011701
- InterPro:   IPR016196
- TIGRFAMs:   TIGR00901

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 47355; Mature: 47224

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb67e46c)-; HASH(0xb617d38)-; HASH(0xca173d8)-; HASH(0x405d332c)-; HASH(0xb1a6860)-; HASH(0xc3a8754)-; HASH(0xca1de2c)-; HASH(0xca174c8)-; HASH(0xc40f228)-; HASH(0xbbdad5c)-; HASH(0xbb30fec)-; HASH(0xca7b7f8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYG
CCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHH
LKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHCCHHHHHHHHH
LCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKF
HHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGL
CCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHH
VQMVTIGGFIWLAAFGHFDVITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYT
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
ATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWVAPLKQENN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KTSSV
CCCCH
>Mature Secondary Structure 
SNSLSSQIFTRKMLICAFTGFNSGLPLFVLSQMLPVWLTDKHLSIELIGAVTGVMLPYG
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHH
LKFLWAPLLDRYFPSFLGRRRSWMLLSQVALLILLYIISLFDPLTQLGTVANIALLIAFF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQDIVLDAYRREILSDHELGLGNTIHINAYRIAGLIPGGLSLYLAAIYPWETVFLWTA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHCCHHHHHHHHH
LCMLAGIFMTLFLAKEPKIDMQQTNQPFYQAFWIPLQEFFQRKGVIQAIGFLLFLFLYKF
HHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GDSFATTLQTKFIYDMGFSKEDIAIVVKSTALWSSILSGLAGGMIMLKLGINRALWLFGL
CCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEHHCCCHHHHHHHH
VQMVTIGGFIWLAAFGHFDVITSAELWKLGVVIAAEYIGVGLGTAAFVAFMARESNPLYT
HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
ATQLALFTSLSALPSKVLGILSGYVVGAVGYYQYFWFCLFLAIPGMLCLFWVAPLKQENN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KTSSV
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1956282; 7542800