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The map label for this gene is hxuB

Identifier: 16272221

GI number: 16272221

Start: 294525

End: 296222

Strand: Direct

Name: hxuB

Synonym: HI0263

Alternate gene names: 16272221

Gene position: 294525-296222 (Clockwise)

Preceding gene: 16272220

Following gene: 16272222

Centisome position: 16.09

GC content: 36.22

Gene sequence:

>1698_bases
ATGAAAATGAGACCTCGTTATTCTGTTATTGCAAGTGCGGTCAGTTTAGGCTTTGTTTTGAGTAAATCAGTGATGGCATT
AGATCGGCCAGATACTGGATCATTGAACCGTGAACTAGAACAACGTCAAATTCAATCAGAAGCCAAACCTAGTGGCGAAT
TATTTAATCAAACGGCAAATTCGCCTTATACTGCACAGTATAAACAAGGACTGAAATTTCCACTTAAGCAAGTACAGATT
TTAGATCGAAACAATCAGGAAGTCGTCACAGACGAGCTTGCACATATTTTAAAAAATTATGTAGGAAAAGAGGTATCGCT
GTCAGATTTAAGTAATTTAGCAAATGAGATCAGCGAATTTTATCGTCATAATAATTATTTAGTGGCAAAAGCAATTTTAC
CACCGCAGGAAATTGAGCAAGGTACGGTAAAAATTTTGTTACTTAAAGGTAATGTAGGCGAAATACGCTTGCAAAATCAC
AGTGCATTAAGCAATAAATTTGTATCCCGTCTCTCTAATACAACAGTGAATGCGTCCGAATTTATTTTGAAAGATGAGTT
AGAAAAATTTGCTTTAACAATAAACGATGTTCCAGGGGTAAATGCTGGTTTGCAACTCTCCGCAGGCAAAAAAGTCGGCG
AAGCGAATTTACTGATTAAAATTAACGATGCAAAACGTTTTTCTAGTTATGTTTCAGTAGATAACCAAGGCAACAAATAT
ACAGGGCGTTACCGTTTGGCTGCGGGGACAAAAGTCAGTAATTTGAATGGCTGGGGCGATGAATTGAAACTGGATTTAAT
GAGTTCTAATCAGGCTAATTTAAAAAATGCTCGTATAGATTATTCCTCTTTAATTGATGGTTATTCTACGCGTTTTGGTG
TAACTGCTAACTATCTCGACTACAAATTAGGTGGTAATTTTAAATCATTACAATCTCAAGGGCATTCCCATACCTTAGGG
GCTTATTTGTTGCACCCAACAATCCGTACACCAAATTTTCGTTTAAGTACTAAAGTGAGCTTTAATCATCAAAACCTTAC
GGATAAACAACAAGCGGTTTATGTGAAACAAAAACGGAAAATAAATAGTTTAACTGCAGGGATTGACGGTTCTTGGAATC
TTATTAAAGATGGGACAACTTATTTTTCATTATCTACCTTGTTCGGTAATTTAGCGAATCAAACTAGTGAAAAAAAACAG
TATACAAAAGAGGATTTTCAACCACAATCGCATTTTACGGTATATAACTACCGCTTGTCTCACGAGCAAATTTTACCAAA
ATCTTTTGCTTTCAATATTGGTATAAACGGTCAGTTTGCCGATAAAACCCTTGAAAGCTCACAGAAAATGTTGCTTGGTG
GTTTGTCTGGAGTACGTGGACATCAAGCTGGTGCGGCTTCTGTGGATGAAGGACATTTGATACAAACAGAATTCAAACAT
TATTTACCAGTCTTTTCCCAAAGTGTGCTAGTTAGTTCATTGTTCTATGACTATGGTTTGGGAAAATATTATAAAAATAG
CCAATTTCTCGAAAAAGGCGTGAAAAATAGCGTGAAATTACAAAGCGTTGGTGCAGGACTTTCTCTTTCAGATGCTGGCA
GCTATGCCATCAATGTCAGTGTCGCCAAACCGCTTGATAACAATATTAATAATGCCGATAAACACCAATTTTGGCTTTCT
ATGATTAAAACTTTCTAA

Upstream 100 bases:

>100_bases
AAATTAGTGCGGTTTATAGCTTCTAAATTTACTTTGGAAAACGCCCTAAAGCTGTTTTCCCTCAATTTTTGTAATTTTAT
CAATTAATAGGACATAAGGA

Downstream 100 bases:

>100_bases
GGAGGTATGCAATGTATAAATTAAATGTAATTTCTCTTATCATTTTGACCACTTACACTGGTGCGACATATGCCTCTGCA
CGGGATTTGCCACAAGGTAG

Product: heme/hemopexin-binding protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MKMRPRYSVIASAVSLGFVLSKSVMALDRPDTGSLNRELEQRQIQSEAKPSGELFNQTANSPYTAQYKQGLKFPLKQVQI
LDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNH
SALSNKFVSRLSNTTVNASEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKY
TGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLG
AYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKQ
YTKEDFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKH
YLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEKGVKNSVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNINNADKHQFWLS
MIKTF

Sequences:

>Translated_565_residues
MKMRPRYSVIASAVSLGFVLSKSVMALDRPDTGSLNRELEQRQIQSEAKPSGELFNQTANSPYTAQYKQGLKFPLKQVQI
LDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNH
SALSNKFVSRLSNTTVNASEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKY
TGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLG
AYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKQ
YTKEDFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKH
YLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEKGVKNSVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNINNADKHQFWLS
MIKTF
>Mature_565_residues
MKMRPRYSVIASAVSLGFVLSKSVMALDRPDTGSLNRELEQRQIQSEAKPSGELFNQTANSPYTAQYKQGLKFPLKQVQI
LDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNH
SALSNKFVSRLSNTTVNASEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKY
TGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLG
AYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKQ
YTKEDFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKH
YLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEKGVKNSVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNINNADKHQFWLS
MIKTF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of huxA

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HXUB1_HAEIN (P44601)

Other databases:

- EMBL:   L42023
- PIR:   D64058
- RefSeq:   NP_438432.1
- ProteinModelPortal:   P44601
- GeneID:   949385
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0263
- NMPDR:   fig|71421.1.peg.248
- TIGR:   HI_0263
- HOGENOM:   HBG495080
- OMA:   DINDSET
- ProtClustDB:   CLSK808399
- BioCyc:   HINF71421:HI_0263-MONOMER
- InterPro:   IPR013686

Pfam domain/function: PF08479 POTRA_2

EC number: NA

Molecular weight: Translated: 62825; Mature: 62825

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMRPRYSVIASAVSLGFVLSKSVMALDRPDTGSLNRELEQRQIQSEAKPSGELFNQTAN
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCC
SPYTAQYKQGLKFPLKQVQILDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEF
CCEEHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNASE
HHCCCEEEEEECCCHHHCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCCCHHH
FILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKY
HHHHHHHHHHEEEECCCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHHHEEECCCCCEE
TGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLD
CCEEEEEECCEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCEECCEE
YKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRK
EECCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
INSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKQYTKEDFQPQSHFTVYNYRLS
HHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
HEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKH
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHH
YLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEKGVKNSVKLQSVGAGLSLSDAGSYAINVS
HHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCEEEEECCCCCEECCCCCEEEEEE
VAKPLDNNINNADKHQFWLSMIKTF
EECCCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MKMRPRYSVIASAVSLGFVLSKSVMALDRPDTGSLNRELEQRQIQSEAKPSGELFNQTAN
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCC
SPYTAQYKQGLKFPLKQVQILDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEF
CCEEHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNASE
HHCCCEEEEEECCCHHHCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHCCCCCCHHH
FILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKY
HHHHHHHHHHEEEECCCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHHHEEECCCCCEE
TGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLD
CCEEEEEECCEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCCCEECCEE
YKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRK
EECCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
INSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKQYTKEDFQPQSHFTVYNYRLS
HHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
HEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKH
HHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHH
YLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEKGVKNSVKLQSVGAGLSLSDAGSYAINVS
HHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCEEEEECCCCCEECCCCCEEEEEE
VAKPLDNNINNADKHQFWLSMIKTF
EECCCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800