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The map label for this gene is nanE

Identifier: 16272112

GI number: 16272112

Start: 160522

End: 161208

Strand: Reverse

Name: nanE

Synonym: HI0145

Alternate gene names: 16272112

Gene position: 161208-160522 (Counterclockwise)

Preceding gene: 16272118

Following gene: 16272111

Centisome position: 8.81

GC content: 42.36

Gene sequence:

>687_bases
ATGTCTAAATTATCTTATCAAGAAGTGCTTTCTCAAATTCAATATGGTCTTATTTCTTCTTGCCAACCTGTCGATGATGG
CCCAATGGATAAACCTGAAATCGTTTCTGCTATGGCTCAGGCTTCAGTTATGGGCGGACGTTCTGGCTTACGTATTGAGG
GTGTTGATAACCTTAAAGCAACCCGTCCTTTTGTGAATGTCCCGATTATCGGAATTGTAAAACGTGATTTGCCTGATAGT
CCCGTGCGTATTACGCCGTTTTTACAAGATATTGAAGATCTAGCCAATGCTGGCGCGGATATTATTGCAGTAGATGGCAC
GAGCCGTCCACGTCCTGTGGATATTGAAAGTGCGGTGAAAAAAATCCACGAAATGGGCTGTTTGGCAATGGCAGATTGTT
CTAATTTAGAAGAAGGCTTGTATTGTAAAGCGCTTGGTTTTGATATTGTCGGCAGTACGATGTCAGGTTATACAGGTGGC
GCAGTGCCAGAAGAACCAGATTATCAATTAGTGAAAGATTTAAAATCAGCGGGTTGTTTTGTGATGGCTGAGGGGCGTTA
TAACACACCAGAATTGGCAAAAGTGGCAATTGAAATTGGTGCAGATTGCGTGACTGTAGGTTCAGCCTTAACTCGTCTTG
AACATATTGTGAGTTGGTTTGCTAATTCAGTGAAATCTGCAAGATAG

Upstream 100 bases:

>100_bases
ATGATGAAAATATAAGCATATTACAACTTATAAAAGATTGTTTTGTGTGGATTAAATTAATTTTAAAGTGATTTATTCAG
ATTTAAATGAGGGGTGTTAT

Downstream 100 bases:

>100_bases
TCGTAAGACGTGTGAGAKAAKGACTTTACACTATAAGGATAAGTTATGCGTTGTTTAGCACTAGATATTGGTGGGACAAA
AATTGCAGCGGCGATTGTAA

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

Sequences:

>Translated_228_residues
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
>Mature_227_residues
SKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDSP
VRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGA
VPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=212, Percent_Identity=61.7924528301887, Blast_Score=259, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_HAEIN (P71340)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_438314.1
- ProteinModelPortal:   P71340
- SMR:   P71340
- GeneID:   951054
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0145
- NMPDR:   fig|71421.1.peg.136
- TIGR:   HI_0145
- HOGENOM:   HBG296941
- OMA:   EHIVSWF
- ProtClustDB:   PRK01130
- BioCyc:   HINF71421:HI_0145-MONOMER
- BRENDA:   5.1.3.9
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 24353; Mature: 24222

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHH
TRPFVNVPIIGIVKRDLPDSPVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVK
CCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
KIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGAVPEEPDYQLVKDLKSAGCF
HHHHHCCHHHHHHCCCCCCCEEEHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEE
VMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGRSGLRIEGVDNLKA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCHH
TRPFVNVPIIGIVKRDLPDSPVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVK
CCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
KIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGGAVPEEPDYQLVKDLKSAGCF
HHHHHCCHHHHHHCCCCCCCEEEHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEE
VMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800