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The map label for this gene is lpxK [H]

Identifier: 16272033

GI number: 16272033

Start: 60321

End: 61319

Strand: Reverse

Name: lpxK [H]

Synonym: HI0059

Alternate gene names: 16272033

Gene position: 61319-60321 (Counterclockwise)

Preceding gene: 16272034

Following gene: 16272032

Centisome position: 3.35

GC content: 39.74

Gene sequence:

>999_bases
ATGCCCTTCTGGTATTCCAACTCCAAACTTATTTGGCTCTTATCGCCTTTTTCTTTATTGTTTTGGTTGATTAGCCAACT
TCGTCGCGCCTTATTCTCTTTGGGGCTGAAGTCTTCTTATCGCGCACCAAAACCAGTGATAATTGTGGGAAATTTGTCTG
TGGGTGGAAATGGCAAAACGCCTGTGGTTGTTTGGCTTATGGAAGAATTAAAAAAACGAGGTCTGCGTGTAGGTGTGATT
TCTCGTGGTTACGGCAGTAAATCTAAAACTTATCCGTTATTCGTCACTAAAAATACAAATCCAATTGAAGGTGGCGATGA
GCCTGTATTGATCGCTAAACGTACTAATGCGCCAGTTGTGATTTCCCCGAATCGCCAGCAAGCGATTGAATTACTCTTAA
GCCAAGCAGAGTGCGATATTATTATTTCTGATGATGGTTTGCAGCATTATCAATTACAACGTGATTTAGAAATTGTCGTA
ATGGACGCTGAGCGCGCATTGGGAAATGGTTTTGTATTGCCAGCAGGTCCATTGCGTGAATTACCAAGTCGATTAAAATC
TGTCGATTTTGTGATCACTAATGGTGGAAAAAATCAGTATTCAGATGCAGTTATGCGTCTTGTGCCTCATTTCGCGATTA
ATTTAAAAACCAATGAAAAACGCCAATTAAATGAATTTCAATCTGGTGTTGCCATCGCAGGGATTGGCAATCCACAGCGT
TTTTTTACTATGTTAGAAAAGTTAGGGATTCAGTTAAAGCAAACTCAAGCATTTCAAGATCATCAACATTTTGAAGCGTC
TCAATTAGAAAAACTTGCTGAAAATCAACCGCTCTTTATGACGGAAAAAGATGCCGTAAAATGCCAATCTTTTGCTAAAG
ATAATTGGTGGTATGTCCCTGTGGATGCGGAGATTATTGAGGCTGAAAAACAACGTGAAAATTTACCGCACTTTTGGGCC
AAAATAGACAAACTTGTGGAGCAATACAGAAATGGCTGA

Upstream 100 bases:

>100_bases
GTTGCATAGTATGCAGTTTACTGGCTAATTTATTGATTATCGAAAACGCGAGTTGAAAAACTCGCGTTATTTTATCCGCA
CTTATTAGAAAGGATTTTCT

Downstream 100 bases:

>100_bases
AAGGATTAATCCCCAGTTGTTTTGATTGCTTGCCGATAAAGCTGAAATATTAAAGAATAAGGAATAAATTATGTCATTTA
CCGTGATTATCCCCGCTCGT

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLMEELKKRGLRVGVI
SRGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVV
MDAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQR
FFTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQRENLPHFWA
KIDKLVEQYRNG

Sequences:

>Translated_332_residues
MPFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLMEELKKRGLRVGVI
SRGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVV
MDAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQR
FFTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQRENLPHFWA
KIDKLVEQYRNG
>Mature_331_residues
PFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLMEELKKRGLRVGVIS
RGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVVM
DAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQRF
FTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQRENLPHFWAK
IDKLVEQYRNG

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=305, Percent_Identity=50.8196721311475, Blast_Score=325, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 37608; Mature: 37477

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKT
CCEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCC
PVVVWLMEELKKRGLRVGVISRGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVV
CEEEHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEE
ISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVVMDAERALGNGFVLPAGPLRE
ECCCHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCEEEEEECHHHCCCCEEECCCHHHH
LPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQR
HHHHHHHEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCEEEEECCCHHH
FFTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVP
HHHHHHHHCCEEHHHHHHHHHHCCCHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEE
VDAEIIEAEKQRENLPHFWAKIDKLVEQYRNG
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKT
CEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCC
PVVVWLMEELKKRGLRVGVISRGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVV
CEEEHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEE
ISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVVMDAERALGNGFVLPAGPLRE
ECCCHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCEEEEEECHHHCCCCEEECCCHHHH
LPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQR
HHHHHHHEEEEEECCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCEEEEECCCHHH
FFTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVP
HHHHHHHHCCEEHHHHHHHHHHCCCHHHHHHHHCCCCEEEECHHHHHHHHHCCCCCEEEE
VDAEIIEAEKQRENLPHFWAKIDKLVEQYRNG
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA