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The map label for this gene is citC

Identifier: 16272000

GI number: 16272000

Start: 26981

End: 27988

Strand: Reverse

Name: citC

Synonym: HI0025

Alternate gene names: 16272000

Gene position: 27988-26981 (Counterclockwise)

Preceding gene: 16272001

Following gene: 16271999

Centisome position: 1.53

GC content: 35.02

Gene sequence:

>1008_bases
ATGCAATTTGAGCGAATTTCTACTGAACAAAAAAAACTTTCTCTCATTCAGACATTTTTACATCAAAATGCGCTTAAATT
AGATGAACAAATCGAGTATTTTGTTGTTGGCTATAATGATAACGAACAAATCGTTGTCTGTGGCGGTTTAGCAGGCAATA
TCATAAAATGTGTTGCGATTGATGAGTCTTTGCGTGGTAGCGGTGTTGCCTTGCAATTAATTACTGAATTGGTTGATTTA
GCTTACACGCTAAAACGTCCACACCTTTTTATTTATACAAAACCCGAATATGCAACGTTGTTCAAATCTTGTGGTTTTTA
TATCATCTCTGATGCCAATCCTTATGTAGTATTATTAGAAAATAGTGCTACGCGTTTACAAAAACAATGCTCATTATGGG
AGAAAATGCGTGTGGATGGTAATCGAATTGGCTCGATTGTAATGAACGCGAATCCATTTACCTTAGGTCATCGTTATTTA
ATTGAGCAAGCATTACAACAATGTGATCATCTGCATTTATTTATTGTCGGTGAAGACGCATCGCAATTTTCTTACACTGA
ACGATTTGAAATGATTCAACAAGGTATTTTCGATTTATCCAATATCACTCTTCATTCTGGCTCTGACTATATTATTTCTC
GTGCAACATTTCCAAATTATTTCCTAAAAGATCAATTAATTACAGATGAAAGTTATTTTGAGATTGATCTGAAGTTATTC
CGTTTACATATTGCTCAAGCTTTGGGAATAACACATCGCTTTGTTGGTACTGAGCTAAATTGTCCCGTCACTGCCGAATA
TAATCGCCAAATGCATTATTGGTTAATGGATGCCGAAATGAATGCACCAAAAATAAATGTTATCGAGATACCTAGAAAAA
CAGCAAGCAACCACATTATTTCTGCTTCTACAGTACGAAAGCATTTGGCTGAAAAAAATTGGGCTCAACTCGCAGAGTTT
GTGCCTATGACTACGTTAAATTATTTACAAAAGTGCGGTCGTTTTTAA

Upstream 100 bases:

>100_bases
ATATGAGCTTATCTTGTATCGTAATTTGCTCATCGCTTATAATAGCTCTATACTACTAACTTGGTAGTGATGTTATGTTT
TCTTCTTTTTTGGAGAGTCG

Downstream 100 bases:

>100_bases
ATACATTTTTATTCATCAATATACGGAAGGAAAATCTATGAAAATAACAAAAGTAGCCGTTGCAGGGACACTGGAATCCA
GTGATGTTCAAGTACGGGTT

Product: citrate lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIQQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWAQLAEF
VPMTTLNYLQKCGRF

Sequences:

>Translated_335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIQQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWAQLAEF
VPMTTLNYLQKCGRF
>Mature_335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIQQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWAQLAEF
VPMTTLNYLQKCGRF

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI87081765, Length=329, Percent_Identity=52.887537993921, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITC_HAEIN (P44462)

Other databases:

- EMBL:   L42023
- PIR:   F64043
- RefSeq:   NP_438198.1
- ProteinModelPortal:   P44462
- GeneID:   950918
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0025
- TIGR:   HI_0025
- HOGENOM:   HBG416494
- OMA:   MNCNPFT
- ProtClustDB:   CLSK874111
- BioCyc:   HINF71421:HI_0025-MONOMER
- BRENDA:   6.2.1.22
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.630.30
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF005751
- SMART:   SM00764
- TIGRFAMs:   TIGR00124
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF08218 Citrate_ly_lig; SSF55729 Acyl_CoA_acyltransferase

EC number: =6.2.1.22

Molecular weight: Translated: 38496; Mature: 38496

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAI
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEE
DESLRGSGVALQLITELVDLAYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLE
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCCEEEEEC
NSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYLIEQALQQCDHLHLFIVGEDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCC
SQFSYTERFEMIQQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCHHHHCEEECCCCEEEHHHHHH
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHII
HHHHHHHHCHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
SASTVRKHLAEKNWAQLAEFVPMTTLNYLQKCGRF
EHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAI
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEE
DESLRGSGVALQLITELVDLAYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLE
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCCEEEEEC
NSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYLIEQALQQCDHLHLFIVGEDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCC
SQFSYTERFEMIQQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCHHHHCEEECCCCEEEHHHHHH
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHII
HHHHHHHHCHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
SASTVRKHLAEKNWAQLAEFVPMTTLNYLQKCGRF
EHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800