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The map label for this gene is uspE

Identifier: 161350020

GI number: 161350020

Start: 1514479

End: 1515408

Strand: Direct

Name: uspE

Synonym: HI1426

Alternate gene names: 161350020

Gene position: 1514479-1515408 (Clockwise)

Preceding gene: 16273330

Following gene: 16273332

Centisome position: 82.75

GC content: 36.67

Gene sequence:

>930_bases
ATGAAATTTAAAAATATTCTCGTTGTACTTAATCCCAGTAATGAAAAACAGTACGCCCTAGCTCGTGCAGTGCGTTTAGT
TGAAGAACAAAAAAATGAAACTAAGGTAAAAATCACCGCACTTTTATCAGTCTATGATTTATCTTATGAAATGTCAGCTT
TACTTTCTTCCGAAGAACGTTCAGAAATGCATCAACAAGTAATTGAAAAACACCGTCACGCTGTTCAATATTACTTAGAT
AAATATGCAAATCCAGAAATTGAATTACAATCTCATATTGTGTGGAATAGCAATGAAGCTGATGCAATTAACGAAGAAGT
AGAAAATAATAATTACGATCTCGTCGTAAAATATACCAAAGACGAAGAAAAACTTACGTCTCTAATCTTTACTCCCATTG
ATTGGCAACTTCTTCGTAAATGCCCTATTCCTGTCTTAATGGTTCGTGATGGCGATTGGAAACATCCACGCCGTATTCTT
GTGGCTGTTAATGTATCTGGAGAGCAAGAATATCAAGATGAATTTAATCAAGAGCTGGTAGAAACTGGTATTTCACTCGC
GGAAAATCTAAATCGTGGTAATGTCCATTTGGTGGCAGCCTACCCTTCCGCGCCAATCAATATGGCGATTGATTTGCCTG
AATTTAATACTTCAGGTTATGAAAACGGTATTCGAGGTCAGCATCTCATTAATATGAAAGCGTTACGTCAGAAGTTTGGG
ATTGATGAAGATCATACTCACGTACGCGAAGGTTTCCCAGAGGAAGTTATTCCTGAAGTGGCGAAAGAAATTGAAGCTGA
ATTAGTGATTTTAGGCACAGTGGGACGCACAGGTTTATCTGCCGCATTATTAGGCAATACTGCAGAACATGTAATTAGTA
AATTAAGTTGTAATTTATTAGGCATTAAACCATCGAAAAAAGACGATTAA

Upstream 100 bases:

>100_bases
CCTTTTTGTGCTTGATAAAAATAAATTTATCCAAATTAATCTTGTACCTTGCCATTTTTGCTATTCTTTTTTATCCTATG
CCTCAATTTTGGAGGCTATT

Downstream 100 bases:

>100_bases
AACATTTTCCTCAATTTATAAGACGCCCTAAATATTTTGTATTTAGGGCGTTTTTATACTATTTCTTATGGTATTTTTCA
TTTTGTGATCTCGATCACAA

Product: universal stress protein UspE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKFKNILVVLNPSNEKQYALARAVRLVEEQKNETKVKITALLSVYDLSYEMSALLSSEERSEMHQQVIEKHRHAVQYYLD
KYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTKDEEKLTSLIFTPIDWQLLRKCPIPVLMVRDGDWKHPRRIL
VAVNVSGEQEYQDEFNQELVETGISLAENLNRGNVHLVAAYPSAPINMAIDLPEFNTSGYENGIRGQHLINMKALRQKFG
IDEDHTHVREGFPEEVIPEVAKEIEAELVILGTVGRTGLSAALLGNTAEHVISKLSCNLLGIKPSKKDD

Sequences:

>Translated_309_residues
MKFKNILVVLNPSNEKQYALARAVRLVEEQKNETKVKITALLSVYDLSYEMSALLSSEERSEMHQQVIEKHRHAVQYYLD
KYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTKDEEKLTSLIFTPIDWQLLRKCPIPVLMVRDGDWKHPRRIL
VAVNVSGEQEYQDEFNQELVETGISLAENLNRGNVHLVAAYPSAPINMAIDLPEFNTSGYENGIRGQHLINMKALRQKFG
IDEDHTHVREGFPEEVIPEVAKEIEAELVILGTVGRTGLSAALLGNTAEHVISKLSCNLLGIKPSKKDD
>Mature_309_residues
MKFKNILVVLNPSNEKQYALARAVRLVEEQKNETKVKITALLSVYDLSYEMSALLSSEERSEMHQQVIEKHRHAVQYYLD
KYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTKDEEKLTSLIFTPIDWQLLRKCPIPVLMVRDGDWKHPRRIL
VAVNVSGEQEYQDEFNQELVETGISLAENLNRGNVHLVAAYPSAPINMAIDLPEFNTSGYENGIRGQHLINMKALRQKFG
IDEDHTHVREGFPEEVIPEVAKEIEAELVILGTVGRTGLSAALLGNTAEHVISKLSCNLLGIKPSKKDD

Specific function: Required for resistance to DNA-damaging agents

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

Organism=Escherichia coli, GI1787594, Length=304, Percent_Identity=49.671052631579, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): USPE_HAEIN (P44195)

Other databases:

- EMBL:   L42023
- PIR:   G64029
- RefSeq:   NP_439575.2
- ProteinModelPortal:   P44195
- GeneID:   950328
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1426
- NMPDR:   fig|71421.1.peg.1358
- TIGR:   HI_1426
- HOGENOM:   HBG638855
- OMA:   YDLSYEM
- ProtClustDB:   PRK11175
- BioCyc:   HINF71421:HI_1426-MONOMER
- GO:   GO:0005737
- InterPro:   IPR014729
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 35087; Mature: 35087

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKNILVVLNPSNEKQYALARAVRLVEEQKNETKVKITALLSVYDLSYEMSALLSSEER
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHCCHHH
SEMHQQVIEKHRHAVQYYLDKYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHCCCCCEEEEEECC
DEEKLTSLIFTPIDWQLLRKCPIPVLMVRDGDWKHPRRILVAVNVSGEQEYQDEFNQELV
CHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
ETGISLAENLNRGNVHLVAAYPSAPINMAIDLPEFNTSGYENGIRGQHLINMKALRQKFG
HHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHC
IDEDHTHVREGFPEEVIPEVAKEIEAELVILGTVGRTGLSAALLGNTAEHVISKLSCNLL
CCCCHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHCCCEE
GIKPSKKDD
ECCCCCCCC
>Mature Secondary Structure
MKFKNILVVLNPSNEKQYALARAVRLVEEQKNETKVKITALLSVYDLSYEMSALLSSEER
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHCCHHH
SEMHQQVIEKHRHAVQYYLDKYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHCCCCCEEEEEECC
DEEKLTSLIFTPIDWQLLRKCPIPVLMVRDGDWKHPRRILVAVNVSGEQEYQDEFNQELV
CHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
ETGISLAENLNRGNVHLVAAYPSAPINMAIDLPEFNTSGYENGIRGQHLINMKALRQKFG
HHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHC
IDEDHTHVREGFPEEVIPEVAKEIEAELVILGTVGRTGLSAALLGNTAEHVISKLSCNLL
CCCCHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHCCCEE
GIKPSKKDD
ECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023