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The map label for this gene is nudL [H]

Identifier: 99082730

GI number: 99082730

Start: 3058901

End: 3059500

Strand: Direct

Name: nudL [H]

Synonym: TM1040_2890

Alternate gene names: 99082730

Gene position: 3058901-3059500 (Clockwise)

Preceding gene: 99082729

Following gene: 99082731

Centisome position: 95.56

GC content: 59.83

Gene sequence:

>600_bases
TTGAGCGCGCTTGCGGAGACCATCGCCAAGGCGCTGACACGCGCTCGCACGGAAACGTCGGATTTCGATCTAAACCCGGA
AACCGTGCTGCCTGCGGGGCGGAAGTTGCGCCCCGCGGGTGTGCTCGTCGGAATTGAGACCTACGGCGCAGTGCCACAGG
TCGTCCTGACAAAGCGCTCCTCCGTGCTCAAACACCACCCCGGCCAGATTGCCTTTCCCGGTGGCAAAGTGGACCCAACG
GACAATGACGCGACTGCTGCCGCCCTAAGGGAAGCGTGGGAAGAAATCGCGTTGCCGCGAGAGCTGCCTCGAATCCTCGG
TCATTTGCCCTGCCACGAAACCGTGACAGGGTTTCAAGTGACCCCCGTGGTTGCGGTCATAGATCAGCCGTTCGAGGCTC
GTGCCGAGGCGGGCGAAGTGGCAGAGGTCTTTCGGGTGCCGCTTTCTCATGTTCTTGATATTGAACGATATCAGATACAA
TCTCGACGCTGGCGCGGCACAAAACGGTTCTACTTTGCGGTGCCATTTGGCCCCTATTACATCTGGGGGGCAACCGCGCG
TATGTTGCGCGGATTTGCTGCGATCATGGACACTCGATGA

Upstream 100 bases:

>100_bases
CCGAGGACGGGCGCGTCACCGCGGATTGTCAGTTCTGCGGCGCGCATTACGATCTTGATCCGGCGACGGTTGGTTTCGAC
GCGGCAGGGGACTGATCCCG

Downstream 100 bases:

>100_bases
AGATTGATGAACCCTGGCTCCATTCTCCTGCGACGCGCAAACTCTGCGATGCGCTGACCTCTGCCGGAGCGGAAATCTAT
TTCGTCGGCGGTTGCGTGCG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSALAETIAKALTRARTETSDFDLNPETVLPAGRKLRPAGVLVGIETYGAVPQVVLTKRSSVLKHHPGQIAFPGGKVDPT
DNDATAAALREAWEEIALPRELPRILGHLPCHETVTGFQVTPVVAVIDQPFEARAEAGEVAEVFRVPLSHVLDIERYQIQ
SRRWRGTKRFYFAVPFGPYYIWGATARMLRGFAAIMDTR

Sequences:

>Translated_199_residues
MSALAETIAKALTRARTETSDFDLNPETVLPAGRKLRPAGVLVGIETYGAVPQVVLTKRSSVLKHHPGQIAFPGGKVDPT
DNDATAAALREAWEEIALPRELPRILGHLPCHETVTGFQVTPVVAVIDQPFEARAEAGEVAEVFRVPLSHVLDIERYQIQ
SRRWRGTKRFYFAVPFGPYYIWGATARMLRGFAAIMDTR
>Mature_198_residues
SALAETIAKALTRARTETSDFDLNPETVLPAGRKLRPAGVLVGIETYGAVPQVVLTKRSSVLKHHPGQIAFPGGKVDPTD
NDATAAALREAWEEIALPRELPRILGHLPCHETVTGFQVTPVVAVIDQPFEARAEAGEVAEVFRVPLSHVLDIERYQIQS
RRWRGTKRFYFAVPFGPYYIWGATARMLRGFAAIMDTR

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=101, Percent_Identity=43.5643564356436, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1788115, Length=142, Percent_Identity=44.3661971830986, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17510677, Length=120, Percent_Identity=35, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536993, Length=175, Percent_Identity=29.7142857142857, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859683, Length=175, Percent_Identity=29.7142857142857, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22004; Mature: 21872

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALAETIAKALTRARTETSDFDLNPETVLPAGRKLRPAGVLVGIETYGAVPQVVLTKRS
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHH
SVLKHHPGQIAFPGGKVDPTDNDATAAALREAWEEIALPRELPRILGHLPCHETVTGFQV
HHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEH
TPVVAVIDQPFEARAEAGEVAEVFRVPLSHVLDIERYQIQSRRWRGTKRFYFAVPFGPYY
HHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCH
IWGATARMLRGFAAIMDTR
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALAETIAKALTRARTETSDFDLNPETVLPAGRKLRPAGVLVGIETYGAVPQVVLTKRS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHH
SVLKHHPGQIAFPGGKVDPTDNDATAAALREAWEEIALPRELPRILGHLPCHETVTGFQV
HHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEH
TPVVAVIDQPFEARAEAGEVAEVFRVPLSHVLDIERYQIQSRRWRGTKRFYFAVPFGPYY
HHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCH
IWGATARMLRGFAAIMDTR
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA