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The map label for this gene is oxyR [H]

Identifier: 99082632

GI number: 99082632

Start: 2953530

End: 2954453

Strand: Direct

Name: oxyR [H]

Synonym: TM1040_2792

Alternate gene names: 99082632

Gene position: 2953530-2954453 (Clockwise)

Preceding gene: 99082630

Following gene: 99082637

Centisome position: 92.27

GC content: 60.06

Gene sequence:

>924_bases
ATGATCAATATCACACTCAAGCAGCTCCGGTACTTCGAGGCGCTCACCCGGCATGGGCATTTTGGACGCGCGGCGGATGC
CTGTGCGATCTCGCAACCTGCCTTGTCAATCCAAATCAAAGAGTTGGAGGAGACGCTTGGCATCGTTTTGTTTGAACGCA
GTGCGCGCCATGTGCGCCTGACAGGTTTCGGACAGGACTTTGCAGAGCGCGCACGAGAAATCCTGCGGTCTGTTGATGAG
TTGGGCGATCTGGCACGCGTCGCACAGGACCGGATGGTCGGTCGGCTCCGCATTGGGGTTATCCCCACGGTTGCGCCCTA
TCTACTGCCTACGCTGATCCAGCGTCTGAACGCCCGGCATGACGGACTTGATGTCCATATCCGCGAAACCCTGACGCAGC
GCCTGATCACGGAACTTTTGGAAGGGCGGCTGGACACAGCGATTGTCGCGCTCCCGGTGTCAGAATCGGGATTGGTCGAA
ACCGCGCTGTTTGAAGAGAAATTCGTCTTGGTCCGTCAGGCTTCGGATGCGGGCGCGCCGGTTCCCTCGCCCGAAGGCAT
GCGCGAAATGAAGCTCTTGTTGCTGGAAGAAGGCCATTGTTTTCGCGATCAGGCCCTGTCCTTTTGCAGCCTGCGTCCGG
CGCTGCCGCGTGACGGGCTGGACGGCAGTTCATTGTCGACACTGGTACAGATGGTGGGCGCCGGTATCGGCGTTACGATC
ATCCCCGAGATGGCCGTCGCTGTGGAGACACGCTCTGCACCCGTCTCTCTTGCTCGTTTCCCAGGAGATGAGCCAGGGCG
CACGATCGGGATGGTCTGGCGCAAGACCAGCCCCCTCGCGCCACAACTACAAGACATCGCAGAGGTGGTGCGAGAGGCTG
CCGAAGCGCTGGCACGCCGAAACAGAGATGTCTTACCGCTCTAG

Upstream 100 bases:

>100_bases
AATCCACAGAAGTCCTGACAGCTGCCCTCACAAATCTTTATAGCAAGAGTTCAGAATTATTCTAAGTTGCATTTTCTCAT
AATCGCTATAAGAAAAACAA

Downstream 100 bases:

>100_bases
GAAAGGGGCTTAGCGCCCCTTCCAGACCGGATCGCGCTTTTCCGCAAATGCGCGCGCGCCTTCAAGATTGTCCTCGGATC
CATAGAGCACATCGACCGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MINITLKQLRYFEALTRHGHFGRAADACAISQPALSIQIKELEETLGIVLFERSARHVRLTGFGQDFAERAREILRSVDE
LGDLARVAQDRMVGRLRIGVIPTVAPYLLPTLIQRLNARHDGLDVHIRETLTQRLITELLEGRLDTAIVALPVSESGLVE
TALFEEKFVLVRQASDAGAPVPSPEGMREMKLLLLEEGHCFRDQALSFCSLRPALPRDGLDGSSLSTLVQMVGAGIGVTI
IPEMAVAVETRSAPVSLARFPGDEPGRTIGMVWRKTSPLAPQLQDIAEVVREAAEALARRNRDVLPL

Sequences:

>Translated_307_residues
MINITLKQLRYFEALTRHGHFGRAADACAISQPALSIQIKELEETLGIVLFERSARHVRLTGFGQDFAERAREILRSVDE
LGDLARVAQDRMVGRLRIGVIPTVAPYLLPTLIQRLNARHDGLDVHIRETLTQRLITELLEGRLDTAIVALPVSESGLVE
TALFEEKFVLVRQASDAGAPVPSPEGMREMKLLLLEEGHCFRDQALSFCSLRPALPRDGLDGSSLSTLVQMVGAGIGVTI
IPEMAVAVETRSAPVSLARFPGDEPGRTIGMVWRKTSPLAPQLQDIAEVVREAAEALARRNRDVLPL
>Mature_307_residues
MINITLKQLRYFEALTRHGHFGRAADACAISQPALSIQIKELEETLGIVLFERSARHVRLTGFGQDFAERAREILRSVDE
LGDLARVAQDRMVGRLRIGVIPTVAPYLLPTLIQRLNARHDGLDVHIRETLTQRLITELLEGRLDTAIVALPVSESGLVE
TALFEEKFVLVRQASDAGAPVPSPEGMREMKLLLLEEGHCFRDQALSFCSLRPALPRDGLDGSSLSTLVQMVGAGIGVTI
IPEMAVAVETRSAPVSLARFPGDEPGRTIGMVWRKTSPLAPQLQDIAEVVREAAEALARRNRDVLPL

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=40.2061855670103, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=31.0483870967742, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788748, Length=307, Percent_Identity=28.9902280130293, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=28.6666666666667, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=30.3754266211604, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693105, Length=280, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787601, Length=258, Percent_Identity=27.1317829457364, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=30.327868852459, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787806, Length=299, Percent_Identity=24.0802675585284, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=307, Percent_Identity=25.0814332247557, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789173, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082132, Length=293, Percent_Identity=23.2081911262799, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790208, Length=264, Percent_Identity=26.8939393939394, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=169, Percent_Identity=26.6272189349112, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693193, Length=155, Percent_Identity=30.3225806451613, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33731; Mature: 33731

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINITLKQLRYFEALTRHGHFGRAADACAISQPALSIQIKELEETLGIVLFERSARHVRL
CCEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHHCEEEEECCCCEEEE
TGFGQDFAERAREILRSVDELGDLARVAQDRMVGRLRIGVIPTVAPYLLPTLIQRLNARH
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCC
DGLDVHIRETLTQRLITELLEGRLDTAIVALPVSESGLVETALFEEKFVLVRQASDAGAP
CCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCCC
VPSPEGMREMKLLLLEEGHCFRDQALSFCSLRPALPRDGLDGSSLSTLVQMVGAGIGVTI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
IPEMAVAVETRSAPVSLARFPGDEPGRTIGMVWRKTSPLAPQLQDIAEVVREAAEALARR
CCHHHHHEECCCCCEEHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
NRDVLPL
CCCCCCC
>Mature Secondary Structure
MINITLKQLRYFEALTRHGHFGRAADACAISQPALSIQIKELEETLGIVLFERSARHVRL
CCEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHHCEEEEECCCCEEEE
TGFGQDFAERAREILRSVDELGDLARVAQDRMVGRLRIGVIPTVAPYLLPTLIQRLNARH
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCC
DGLDVHIRETLTQRLITELLEGRLDTAIVALPVSESGLVETALFEEKFVLVRQASDAGAP
CCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCCC
VPSPEGMREMKLLLLEEGHCFRDQALSFCSLRPALPRDGLDGSSLSTLVQMVGAGIGVTI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
IPEMAVAVETRSAPVSLARFPGDEPGRTIGMVWRKTSPLAPQLQDIAEVVREAAEALARR
CCHHHHHEECCCCCEEHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
NRDVLPL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]