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The map label for this gene is glnA [H]

Identifier: 99082623

GI number: 99082623

Start: 2942601

End: 2943953

Strand: Reverse

Name: glnA [H]

Synonym: TM1040_2783

Alternate gene names: 99082623

Gene position: 2943953-2942601 (Counterclockwise)

Preceding gene: 99082624

Following gene: 99082622

Centisome position: 91.97

GC content: 58.76

Gene sequence:

>1353_bases
ATGACTTTCGAGGATCTCAAGGAACAGATCGCAGCCGGACAAGTGGATACGGTTTTGGTTTGCATTGTGGACATGCAAGG
CCGCCTGATGGGCAAACGCTTCCACGCCGAGGCCTTCCTCGAAATGGCAGACGGCGAGACCCACTGCTGCAACTACTTGC
TGGCCACCGATCTCGCGATGGCGACACCGGATGGCTATGCCTCAACCAGCTGGGAACGCGGCTACGGCGACTACATCATG
AAGCCGGACCTGACGACGCTGCGCCCGGTTCCGTGGCTTGAGGGAACTGCGATGGTGCTTTGTGATGTCATCGACCATCA
CACCCACGCACCAGTCGCGCATTCGCCGCGTGAGATGCTCAAGGCGCAGATCGCGCGCTGCGAGGCGTTGGGGCTGTCGC
CCGTGATGGCAACCGAGCTTGAGTTCTTCCTGTTCAAAGGCACCCATGACGAGATCGCCGCTGGCGGCTTTAACAAGCTC
GAGCCGATCTCAACCTACAACGAAGACTACAGCATCATGCAGACCTCCAAAGAGGAGCCTGTGATGCGCCCGATCCGCAA
TCACCTGCGCGCCATGGGGCTCCCGATCGAGGGCTCCAAAGGCGAGGCAGAGGCCGGCCAAGAAGAGCTGAACATCAAGT
ATGACGCGGCGCTGGCAACGGCCGATCATCACACGATCGCAAAACATGGCATCAAGGAGATCGCGCATCAGCAGGGTTTT
GCGGCGACGTTCCTTCCCAAATGGCACCACGAACGGGTCGGGTCTGCTGCGCATGTGCATCAGTCGCTTTGGAAGGATGG
CGGCAACGCCTTCTTTGACGAGAGCGCGCCGCTCGGAAAATCAAAGCTGATGGACCACTATATGGCGGGTTTGTTGAAAT
ACGCCGCCGACTACACCTATTTCATGGCGCCCTATATCAACAGCTACAAGCGGTTTGCCAAAGGCACTTTTGCACCTACG
CAGGTGGTTTGGTCTGTTGATAACCGCACGGCGGCCTTCCGCCTCTGTGGCGATGGAACCAAGGGTGTTCGGGTTGAATG
CCGGGTTCCGGGTTCCGACATGAACCCTTATCTGGCGCAGGCTGCGATGTTGGCGGCTGGGCTCAAGGGCATCGAGGAAA
AACTGGAACTGCAGGACCCGTTCAATGGCGATGCCTATGCTGGCGACACACAACAGCATATCCCGCGCAGCCTGCTGGAA
GCGCGTAAGGCGCTGTTGGGCTCCGAGATGCTGCGCGAGGCCTTTGGTGAAGACGTGATCACGCACTATGCCCGCGCGGC
AGAGTGGGAGATTGAAGAATTCAATCGCGTTGTGACCGACTATGAGGTCGCGCGCGGGTTTGAGAAAGCCTGA

Upstream 100 bases:

>100_bases
CGGTCGTCCGTATCGTTACGGCTGATCACACGTGCAATAGCAATCAATGTCGGGGGCGGGGTTTCACTCTGCCCCCTGTC
AAAACAACAGGGAACGCCAG

Downstream 100 bases:

>100_bases
TATCCGCTGGGCGGGCGGGGGCCAGCCCCCGCACCCCCGGGATATTTGGGAGAAGATGAAGATAATCGGGGCCGTATCCT
GCGCCCCCGGAGGAGTTGGC

Product: L-glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTFEDLKEQIAAGQVDTVLVCIVDMQGRLMGKRFHAEAFLEMADGETHCCNYLLATDLAMATPDGYASTSWERGYGDYIM
KPDLTTLRPVPWLEGTAMVLCDVIDHHTHAPVAHSPREMLKAQIARCEALGLSPVMATELEFFLFKGTHDEIAAGGFNKL
EPISTYNEDYSIMQTSKEEPVMRPIRNHLRAMGLPIEGSKGEAEAGQEELNIKYDAALATADHHTIAKHGIKEIAHQQGF
AATFLPKWHHERVGSAAHVHQSLWKDGGNAFFDESAPLGKSKLMDHYMAGLLKYAADYTYFMAPYINSYKRFAKGTFAPT
QVVWSVDNRTAAFRLCGDGTKGVRVECRVPGSDMNPYLAQAAMLAAGLKGIEEKLELQDPFNGDAYAGDTQQHIPRSLLE
ARKALLGSEMLREAFGEDVITHYARAAEWEIEEFNRVVTDYEVARGFEKA

Sequences:

>Translated_450_residues
MTFEDLKEQIAAGQVDTVLVCIVDMQGRLMGKRFHAEAFLEMADGETHCCNYLLATDLAMATPDGYASTSWERGYGDYIM
KPDLTTLRPVPWLEGTAMVLCDVIDHHTHAPVAHSPREMLKAQIARCEALGLSPVMATELEFFLFKGTHDEIAAGGFNKL
EPISTYNEDYSIMQTSKEEPVMRPIRNHLRAMGLPIEGSKGEAEAGQEELNIKYDAALATADHHTIAKHGIKEIAHQQGF
AATFLPKWHHERVGSAAHVHQSLWKDGGNAFFDESAPLGKSKLMDHYMAGLLKYAADYTYFMAPYINSYKRFAKGTFAPT
QVVWSVDNRTAAFRLCGDGTKGVRVECRVPGSDMNPYLAQAAMLAAGLKGIEEKLELQDPFNGDAYAGDTQQHIPRSLLE
ARKALLGSEMLREAFGEDVITHYARAAEWEIEEFNRVVTDYEVARGFEKA
>Mature_449_residues
TFEDLKEQIAAGQVDTVLVCIVDMQGRLMGKRFHAEAFLEMADGETHCCNYLLATDLAMATPDGYASTSWERGYGDYIMK
PDLTTLRPVPWLEGTAMVLCDVIDHHTHAPVAHSPREMLKAQIARCEALGLSPVMATELEFFLFKGTHDEIAAGGFNKLE
PISTYNEDYSIMQTSKEEPVMRPIRNHLRAMGLPIEGSKGEAEAGQEELNIKYDAALATADHHTIAKHGIKEIAHQQGFA
ATFLPKWHHERVGSAAHVHQSLWKDGGNAFFDESAPLGKSKLMDHYMAGLLKYAADYTYFMAPYINSYKRFAKGTFAPTQ
VVWSVDNRTAAFRLCGDGTKGVRVECRVPGSDMNPYLAQAAMLAAGLKGIEEKLELQDPFNGDAYAGDTQQHIPRSLLEA
RKALLGSEMLREAFGEDVITHYARAAEWEIEEFNRVVTDYEVARGFEKA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=365, Percent_Identity=27.6712328767123, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI87081870, Length=445, Percent_Identity=29.6629213483146, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790301, Length=407, Percent_Identity=28.992628992629, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50032; Mature: 49901

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEDLKEQIAAGQVDTVLVCIVDMQGRLMGKRFHAEAFLEMADGETHCCNYLLATDLAM
CCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ATPDGYASTSWERGYGDYIMKPDLTTLRPVPWLEGTAMVLCDVIDHHTHAPVAHSPREML
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
KAQIARCEALGLSPVMATELEFFLFKGTHDEIAAGGFNKLEPISTYNEDYSIMQTSKEEP
HHHHHHHHHCCCCCHHHHHHEEEEEECCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCH
VMRPIRNHLRAMGLPIEGSKGEAEAGQEELNIKYDAALATADHHTIAKHGIKEIAHQQGF
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCEEEHHEEECCCHHHHHHHHHHHHHHHCCC
AATFLPKWHHERVGSAAHVHQSLWKDGGNAFFDESAPLGKSKLMDHYMAGLLKYAADYTY
EEECCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FMAPYINSYKRFAKGTFAPTQVVWSVDNRTAAFRLCGDGTKGVRVECRVPGSDMNPYLAQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHH
AAMLAAGLKGIEEKLELQDPFNGDAYAGDTQQHIPRSLLEARKALLGSEMLREAFGEDVI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
THYARAAEWEIEEFNRVVTDYEVARGFEKA
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFEDLKEQIAAGQVDTVLVCIVDMQGRLMGKRFHAEAFLEMADGETHCCNYLLATDLAM
CHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ATPDGYASTSWERGYGDYIMKPDLTTLRPVPWLEGTAMVLCDVIDHHTHAPVAHSPREML
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
KAQIARCEALGLSPVMATELEFFLFKGTHDEIAAGGFNKLEPISTYNEDYSIMQTSKEEP
HHHHHHHHHCCCCCHHHHHHEEEEEECCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCH
VMRPIRNHLRAMGLPIEGSKGEAEAGQEELNIKYDAALATADHHTIAKHGIKEIAHQQGF
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCEEEHHEEECCCHHHHHHHHHHHHHHHCCC
AATFLPKWHHERVGSAAHVHQSLWKDGGNAFFDESAPLGKSKLMDHYMAGLLKYAADYTY
EEECCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FMAPYINSYKRFAKGTFAPTQVVWSVDNRTAAFRLCGDGTKGVRVECRVPGSDMNPYLAQ
HHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCEEEEEECCCCCCCHHHHH
AAMLAAGLKGIEEKLELQDPFNGDAYAGDTQQHIPRSLLEARKALLGSEMLREAFGEDVI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
THYARAAEWEIEEFNRVVTDYEVARGFEKA
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1348781; 10360571 [H]