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The map label for this gene is bkdR [H]

Identifier: 99082620

GI number: 99082620

Start: 2939325

End: 2939792

Strand: Direct

Name: bkdR [H]

Synonym: TM1040_2780

Alternate gene names: 99082620

Gene position: 2939325-2939792 (Clockwise)

Preceding gene: 99082614

Following gene: 99082628

Centisome position: 91.83

GC content: 58.55

Gene sequence:

>468_bases
ATGTTGGCGAAATACGCTGCAGACCGATTGGACCGCGCGATTCTACGCGCCCTCCGCGAGGATGGCCGCATGTCGTTGGT
ACAATTGTCGGAACGTGTTGGATTGTCTGCGACCCCGGTCAAACGACGCCTGCGCCAGCTCGAAGATAGCGGCTTGATCG
AGGGTTATGTGGCGCGGATCGACCGTAAGGCCGCCGGATTTGGCATCACCGCATTTGTCTCGGTTGAGCTTGAAAAACAG
GACGCCGAAGCTGTCGCGAGCTTTCAGCGAAAAGTGGCACGGTTTGAAGAGGTCGTGACCGGGAGCCTGATGACGGGTGC
GCAAGATTTCCTGTTGGAGGTGGTCGTGGAGAGCCTGGAGGAATTCGAGACCTTCCTGCAAACCAAACTCATGCGCGTGG
AGGGGCTGCGCGCGGTGCGGTCACGATTTGCGCTGCGCAAGTTTATTGATCGTGCCCGCATCCCTTGA

Upstream 100 bases:

>100_bases
AATCTGATTTGGAGATTTTATCGCGAAACACTGGTGGAAAAATTCCATATCCCCCATAATAACACGCAAACATTAGTGCT
TATCACTACACAAGGGGTTT

Downstream 100 bases:

>100_bases
TTTGCGCAGTACCGCACAAAAAGAGACCGCGCCCAGATCCTGGGCACGGCCTCTTCCTCGGTGTTTCGGGGACCGATTAT
TCTATCAAAGCGCGGCTTTG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MLAKYAADRLDRAILRALREDGRMSLVQLSERVGLSATPVKRRLRQLEDSGLIEGYVARIDRKAAGFGITAFVSVELEKQ
DAEAVASFQRKVARFEEVVTGSLMTGAQDFLLEVVVESLEEFETFLQTKLMRVEGLRAVRSRFALRKFIDRARIP

Sequences:

>Translated_155_residues
MLAKYAADRLDRAILRALREDGRMSLVQLSERVGLSATPVKRRLRQLEDSGLIEGYVARIDRKAAGFGITAFVSVELEKQ
DAEAVASFQRKVARFEEVVTGSLMTGAQDFLLEVVVESLEEFETFLQTKLMRVEGLRAVRSRFALRKFIDRARIP
>Mature_155_residues
MLAKYAADRLDRAILRALREDGRMSLVQLSERVGLSATPVKRRLRQLEDSGLIEGYVARIDRKAAGFGITAFVSVELEKQ
DAEAVASFQRKVARFEEVVTGSLMTGAQDFLLEVVVESLEEFETFLQTKLMRVEGLRAVRSRFALRKFIDRARIP

Specific function: Positive regulator of the bkd operon for branched-chain keto acid dehydrogenase complex [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=148, Percent_Identity=33.7837837837838, Blast_Score=95, Evalue=2e-21,
Organism=Escherichia coli, GI1787116, Length=134, Percent_Identity=35.8208955223881, Blast_Score=92, Evalue=1e-20,
Organism=Escherichia coli, GI1790182, Length=156, Percent_Identity=25.6410256410256, Blast_Score=63, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17535; Mature: 17535

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKYAADRLDRAILRALREDGRMSLVQLSERVGLSATPVKRRLRQLEDSGLIEGYVARI
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
DRKAAGFGITAFVSVELEKQDAEAVASFQRKVARFEEVVTGSLMTGAQDFLLEVVVESLE
HHHHCCCCHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFETFLQTKLMRVEGLRAVRSRFALRKFIDRARIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLAKYAADRLDRAILRALREDGRMSLVQLSERVGLSATPVKRRLRQLEDSGLIEGYVARI
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHH
DRKAAGFGITAFVSVELEKQDAEAVASFQRKVARFEEVVTGSLMTGAQDFLLEVVVESLE
HHHHCCCCHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFETFLQTKLMRVEGLRAVRSRFALRKFIDRARIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]