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The map label for this gene is appC [H]

Identifier: 99082583

GI number: 99082583

Start: 2887867

End: 2888775

Strand: Reverse

Name: appC [H]

Synonym: TM1040_2743

Alternate gene names: 99082583

Gene position: 2888775-2887867 (Counterclockwise)

Preceding gene: 99082584

Following gene: 99082582

Centisome position: 90.25

GC content: 60.95

Gene sequence:

>909_bases
ATGTCAGATCTCCTTCGTACCTTTCTGCGCAATCGCAAGGCCGCTATCGGGCTCACCATCGTGCTGATCTATGTGGCGAT
TGCGATTGCCGCGCCCCTGATCGCACCGTTTGATCCCATTGCCCGCGTGGGCCGTCCGCATCAGCCGCCCTCGGTCGAAC
ACTGGCTCGGGACCACCCGCATGGGGCGCGACGTGTTCAGCCAGTTGGTCTGGGGCACGCGTACCTCGCTGATGGTGGGG
ATTGTTGCCGGCCTGATCGTGACCGCGATTGGCACCTTCATCGGCATCACCGCTGCCTATTTTGGCGGCCTTGTGGATGA
TATCCTCAACTTCTTTACCAATGTGGTTCTGGTGCTGCCACAACTGCCGCTCCTGCTGGTTCTGGCCGCTTTCCTCGGTC
AGGTCGGACCCTGGGCGATCGCGCTTATTATCGGTCTGACCTCCTGGGCCTGGGGCGCACGCGTCACCCGTGCACAGGCG
ATGTCGCTCAAGACCCGCGACTTTATTCAGGCCTCCGCGATGATCGGAGAGCCTACGTGGCGGATGATCCTTGTCGAGAT
GCTGCCGAACCTGCTGTCGATCATAGGGTTCAACTTTATCGGCTCCGTCATTTTCACCATCATCACCGAGGCCACGCTTG
AATTCCTCGGCCTTGGCAGCCCCTTGGCCCTGTCGTGGGGCACCATGCTTTATAATGCGCAGACCGCTTCGGCGATCATG
GTTGGCGCATGGTGGGAGGTTCTGGCCCCTTGTGCGGCGATCGTGCTGATCGGTGTCGGCCTGTCGCTGATGAACTTCGG
CGTGGACGAGATCGCAAACCCCCGGATGCGCACCCTTGGCAATGTCGCCAAGGCGCTGCGGATCGAAAAGCGCTTGCTGC
GCCAACGCATGCAGGAGGCCGAGCAATGA

Upstream 100 bases:

>100_bases
TCCAGGGCCAGCTTCTCATCATGACACTTGCCATGCTGCTCGCGAACCTCGCGGTGGACCTGGCCTACGTCTTCCTTGAC
CCCCGACTGAAGAGGGCCTG

Downstream 100 bases:

>100_bases
GCGCCCTTCTTTCCGTCGAGGGCCTGCGGGTCGATTATCTGACTGCAGGCGCGCCTTTTACCGCCGTTCGGGACATCTCT
TTTGAGATCCAGCCCAATGA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSDLLRTFLRNRKAAIGLTIVLIYVAIAIAAPLIAPFDPIARVGRPHQPPSVEHWLGTTRMGRDVFSQLVWGTRTSLMVG
IVAGLIVTAIGTFIGITAAYFGGLVDDILNFFTNVVLVLPQLPLLLVLAAFLGQVGPWAIALIIGLTSWAWGARVTRAQA
MSLKTRDFIQASAMIGEPTWRMILVEMLPNLLSIIGFNFIGSVIFTIITEATLEFLGLGSPLALSWGTMLYNAQTASAIM
VGAWWEVLAPCAAIVLIGVGLSLMNFGVDEIANPRMRTLGNVAKALRIEKRLLRQRMQEAEQ

Sequences:

>Translated_302_residues
MSDLLRTFLRNRKAAIGLTIVLIYVAIAIAAPLIAPFDPIARVGRPHQPPSVEHWLGTTRMGRDVFSQLVWGTRTSLMVG
IVAGLIVTAIGTFIGITAAYFGGLVDDILNFFTNVVLVLPQLPLLLVLAAFLGQVGPWAIALIIGLTSWAWGARVTRAQA
MSLKTRDFIQASAMIGEPTWRMILVEMLPNLLSIIGFNFIGSVIFTIITEATLEFLGLGSPLALSWGTMLYNAQTASAIM
VGAWWEVLAPCAAIVLIGVGLSLMNFGVDEIANPRMRTLGNVAKALRIEKRLLRQRMQEAEQ
>Mature_301_residues
SDLLRTFLRNRKAAIGLTIVLIYVAIAIAAPLIAPFDPIARVGRPHQPPSVEHWLGTTRMGRDVFSQLVWGTRTSLMVGI
VAGLIVTAIGTFIGITAAYFGGLVDDILNFFTNVVLVLPQLPLLLVLAAFLGQVGPWAIALIIGLTSWAWGARVTRAQAM
SLKTRDFIQASAMIGEPTWRMILVEMLPNLLSIIGFNFIGSVIFTIITEATLEFLGLGSPLALSWGTMLYNAQTASAIMV
GAWWEVLAPCAAIVLIGVGLSLMNFGVDEIANPRMRTLGNVAKALRIEKRLLRQRMQEAEQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=30.8243727598566, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=30.8880308880309, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=34.7222222222222, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787498, Length=280, Percent_Identity=29.6428571428571, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789889, Length=207, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788505, Length=177, Percent_Identity=32.7683615819209, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32824; Mature: 32692

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLLRTFLRNRKAAIGLTIVLIYVAIAIAAPLIAPFDPIARVGRPHQPPSVEHWLGTTR
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHH
MGRDVFSQLVWGTRTSLMVGIVAGLIVTAIGTFIGITAAYFGGLVDDILNFFTNVVLVLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLPLLLVLAAFLGQVGPWAIALIIGLTSWAWGARVTRAQAMSLKTRDFIQASAMIGEPTW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RMILVEMLPNLLSIIGFNFIGSVIFTIITEATLEFLGLGSPLALSWGTMLYNAQTASAIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHH
VGAWWEVLAPCAAIVLIGVGLSLMNFGVDEIANPRMRTLGNVAKALRIEKRLLRQRMQEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EQ
CC
>Mature Secondary Structure 
SDLLRTFLRNRKAAIGLTIVLIYVAIAIAAPLIAPFDPIARVGRPHQPPSVEHWLGTTR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHH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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]