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The map label for this gene is mop [H]

Identifier: 99082545

GI number: 99082545

Start: 2847805

End: 2850138

Strand: Direct

Name: mop [H]

Synonym: TM1040_2705

Alternate gene names: 99082545

Gene position: 2847805-2850138 (Clockwise)

Preceding gene: 99082544

Following gene: 99082546

Centisome position: 88.97

GC content: 62.47

Gene sequence:

>2334_bases
ATGAAAGATCTGGGCAATACCACAGAGATCAAAGGTGCCGCGCATCAGGATCTCAAACACGAGAGCGCCATCAAACAGGT
GCAGGGCCGCGCCGACTACACCGACGACATCCTGGAACCCGCAGGCACGCTGCATGCCTATCTCGGCGTGTCTACCGTCG
CCCATGCCAACATCCGCGGCATGGATCTGAGCCGTGTGCGCGCCGCGCCCGGTGTCGTCGATGTGCTGACAGCGGATGAT
ATTCCCGGCGTTAATGACGTGAGCCCCACGGGCAAACATGACGAGCCGGTGTTTCCAACCGAGAAGGTGGAGTTTCATGG
CCAGCCGCTCTTTGCGGTGATTGCCGAGAGCCGCGATGCCGCACGCCGCGCCGCGGAGCTTGCGGATGTAGACTATGAGG
TGCTGCCCCACGCGCTCGATGCGATTTCGGCGCGGGATGCGGGGTTGCCCATGGTCACCGACCCGCTGAAGCTCGAGCGC
GGTGATGTGGAAAGCGGCCTTGCGGAGGCACCGCACCGGTTGCAGGGACGCGTTGTCGTCGGCGGTCAGGATCACATGTA
TCTCGAAGGCCATATCGCCTTTGCGATTCCGGGCGAAGATGACGATGTGGTGGTGCATTGCTCCACCCAGCATCCGAGCG
AGGCGCAGCACATGGTGTCCCATGTGCTCGGCGTGCCGTCGAATGCGGTGGTGGTGAACGTGCGCCGCATGGGCGGGGGG
TTTGGCGGCAAGGAAAGCCAGATGAATCTGTTCTGCGCCTTTGCCGCCCTTGGCGCCAAGAAGCTGAACCGTCCGGTGAA
AATCCGCCCCGACCGCGATCAGGACATGACTGCCACCGGCAAGCGGCATGACTTTGTGATCGACTATGATCTGGGCTTTG
ACAATGAGGGGCGGATCGAAGCCGTCGAGAGCCAGTTTGCCGCGCGCTGCGGCTATTCCTCGGACCTCTCCGGCCCCGTG
ACCGACCGCGCGCTGTTTCATGCCGACAACGCCTATTTCTACCCCAATGTCCGTCTGACCTCCTGTCCGCAGAAGACGAA
TACAGTCTCTAACACGGCATTTAGAGGCTTTGGCGGCCCGCAGGGCGTGGTCGCCGCGGAACGAATGATCGAGGAAATCG
CCTATGCGCTGGGCAAGGACCCGCTGGAGGTGCGCAAGGCGAATTTCTACGGCCAACCCGGTGATGGCCGCACCCTCACG
CCCTATCATCAGGAGGTGGAGGACAATGTGATCGGTCGCATTGTCGAGGAACTGGAAGAGAGCAGCGACTATCAGGCCCG
CCGCGCGGCGATCATTGCCGAGAACACAAAGGGCGGCATCATCCGTCGTGGCATCGCGCTGACACCGGTCAAATTCGGCA
TCTCCTTTACTGCCACGTGGTACAATCAGGCCGGCGCTCTGATCCACATCTACAACGATGGCTCGATCCACCTCAATCAT
GGCGGCACCGAGATGGGGCAGGGCCTCAACACCAAGGTCGCGCAGGTGGTGGCCGAGGCGTTTCAGGTCGATTTCGACCG
CATCAAGATCACCAAGACCACGACCGAAAAAGTCCCGAACACCTCTGCCACGGCGGCCTCTTCGGGGTCCGACCTCAACG
GGATGGCGGCGCTGGATGCCTGCGAGCAGATCAAGGCGCGGCTGGTGAAATTTGCCGCCGAGAGCCGGGGCGTGGCCGAA
AGCGCCGTGCGCTTTGGACCCAACCAGATCCGCATCGGCGAGGAGGTGGTGGACTTTGCCGCCTTTATCCGCGAGGCCTA
TATGGCGCGGGTGCATCTGTCGGCGGCAGGGTTCTACAAGACGCCCAAGATCCATTGGGACCGTGCGGCGGGCAAGGGAC
GGCCGTTCTACTATTACGCCTATGGCGCGTCCTGCTCGGAGGTTTCCATCGATACGCTCACCGGCGAGTACCGGGTGGAG
CGCACCGACATCCTGCATGACGTGGGCCGATCCCTTAATCCGATCCTCGACAAGGGGCAGGTCGAAGGCGCGTTTATTCA
GGGCATGGGCTGGCTCACCACAGAGGAGCTCTGGTGGGACAAAGACGGGCGCCTGCGCACCCATGCGCCTTCGACCTACA
AGATCCCGCTGGCCTCTGACCGCCCGCGCAGCTTCAACGTGAAGCTCGCCGACTGGTCTGAAAACCGCGAGATGACCATC
AAACGCTCTAAGGCGGTGGGCGAGCCGCCCTTCATGCTGGGGATTTCTGTTCTGGAGGCGCTGTCGATGGCGGTGGCCTC
GGTTGCCGACTATCGTGAGTGCCCGCGTCTTGAGGCCCCCGCCACGCCCGAACGCGTGCTGATGGCGGTGGAACGTCTTA
AGGCCGGAGGCTGA

Upstream 100 bases:

>100_bases
TGACCGTCGCCGCGAACCTGTTGCGCCGGTTCTACCTCGAACAAGACAGCACCCAGGGCGCACCCGTGCGTCTGGCCATC
GCGTGAGGGAGGAGACACCT

Downstream 100 bases:

>100_bases
GGCCATGCAGGCAGAGCAGCTTCGTGCATTTCTTGACGCCCCGGGCCCGGTTGCGAGCCTGCGGCTCACGAGGGTTCGCG
GGTCCTCTCCGCGCAACACG

Product: xanthine oxidase / xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: Molybdenum iron sulfur protein [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MKDLGNTTEIKGAAHQDLKHESAIKQVQGRADYTDDILEPAGTLHAYLGVSTVAHANIRGMDLSRVRAAPGVVDVLTADD
IPGVNDVSPTGKHDEPVFPTEKVEFHGQPLFAVIAESRDAARRAAELADVDYEVLPHALDAISARDAGLPMVTDPLKLER
GDVESGLAEAPHRLQGRVVVGGQDHMYLEGHIAFAIPGEDDDVVVHCSTQHPSEAQHMVSHVLGVPSNAVVVNVRRMGGG
FGGKESQMNLFCAFAALGAKKLNRPVKIRPDRDQDMTATGKRHDFVIDYDLGFDNEGRIEAVESQFAARCGYSSDLSGPV
TDRALFHADNAYFYPNVRLTSCPQKTNTVSNTAFRGFGGPQGVVAAERMIEEIAYALGKDPLEVRKANFYGQPGDGRTLT
PYHQEVEDNVIGRIVEELEESSDYQARRAAIIAENTKGGIIRRGIALTPVKFGISFTATWYNQAGALIHIYNDGSIHLNH
GGTEMGQGLNTKVAQVVAEAFQVDFDRIKITKTTTEKVPNTSATAASSGSDLNGMAALDACEQIKARLVKFAAESRGVAE
SAVRFGPNQIRIGEEVVDFAAFIREAYMARVHLSAAGFYKTPKIHWDRAAGKGRPFYYYAYGASCSEVSIDTLTGEYRVE
RTDILHDVGRSLNPILDKGQVEGAFIQGMGWLTTEELWWDKDGRLRTHAPSTYKIPLASDRPRSFNVKLADWSENREMTI
KRSKAVGEPPFMLGISVLEALSMAVASVADYRECPRLEAPATPERVLMAVERLKAGG

Sequences:

>Translated_777_residues
MKDLGNTTEIKGAAHQDLKHESAIKQVQGRADYTDDILEPAGTLHAYLGVSTVAHANIRGMDLSRVRAAPGVVDVLTADD
IPGVNDVSPTGKHDEPVFPTEKVEFHGQPLFAVIAESRDAARRAAELADVDYEVLPHALDAISARDAGLPMVTDPLKLER
GDVESGLAEAPHRLQGRVVVGGQDHMYLEGHIAFAIPGEDDDVVVHCSTQHPSEAQHMVSHVLGVPSNAVVVNVRRMGGG
FGGKESQMNLFCAFAALGAKKLNRPVKIRPDRDQDMTATGKRHDFVIDYDLGFDNEGRIEAVESQFAARCGYSSDLSGPV
TDRALFHADNAYFYPNVRLTSCPQKTNTVSNTAFRGFGGPQGVVAAERMIEEIAYALGKDPLEVRKANFYGQPGDGRTLT
PYHQEVEDNVIGRIVEELEESSDYQARRAAIIAENTKGGIIRRGIALTPVKFGISFTATWYNQAGALIHIYNDGSIHLNH
GGTEMGQGLNTKVAQVVAEAFQVDFDRIKITKTTTEKVPNTSATAASSGSDLNGMAALDACEQIKARLVKFAAESRGVAE
SAVRFGPNQIRIGEEVVDFAAFIREAYMARVHLSAAGFYKTPKIHWDRAAGKGRPFYYYAYGASCSEVSIDTLTGEYRVE
RTDILHDVGRSLNPILDKGQVEGAFIQGMGWLTTEELWWDKDGRLRTHAPSTYKIPLASDRPRSFNVKLADWSENREMTI
KRSKAVGEPPFMLGISVLEALSMAVASVADYRECPRLEAPATPERVLMAVERLKAGG
>Mature_777_residues
MKDLGNTTEIKGAAHQDLKHESAIKQVQGRADYTDDILEPAGTLHAYLGVSTVAHANIRGMDLSRVRAAPGVVDVLTADD
IPGVNDVSPTGKHDEPVFPTEKVEFHGQPLFAVIAESRDAARRAAELADVDYEVLPHALDAISARDAGLPMVTDPLKLER
GDVESGLAEAPHRLQGRVVVGGQDHMYLEGHIAFAIPGEDDDVVVHCSTQHPSEAQHMVSHVLGVPSNAVVVNVRRMGGG
FGGKESQMNLFCAFAALGAKKLNRPVKIRPDRDQDMTATGKRHDFVIDYDLGFDNEGRIEAVESQFAARCGYSSDLSGPV
TDRALFHADNAYFYPNVRLTSCPQKTNTVSNTAFRGFGGPQGVVAAERMIEEIAYALGKDPLEVRKANFYGQPGDGRTLT
PYHQEVEDNVIGRIVEELEESSDYQARRAAIIAENTKGGIIRRGIALTPVKFGISFTATWYNQAGALIHIYNDGSIHLNH
GGTEMGQGLNTKVAQVVAEAFQVDFDRIKITKTTTEKVPNTSATAASSGSDLNGMAALDACEQIKARLVKFAAESRGVAE
SAVRFGPNQIRIGEEVVDFAAFIREAYMARVHLSAAGFYKTPKIHWDRAAGKGRPFYYYAYGASCSEVSIDTLTGEYRVE
RTDILHDVGRSLNPILDKGQVEGAFIQGMGWLTTEELWWDKDGRLRTHAPSTYKIPLASDRPRSFNVKLADWSENREMTI
KRSKAVGEPPFMLGISVLEALSMAVASVADYRECPRLEAPATPERVLMAVERLKAGG

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=771, Percent_Identity=42.2827496757458, Blast_Score=579, Evalue=1e-165,
Organism=Homo sapiens, GI71773480, Length=760, Percent_Identity=36.5789473684211, Blast_Score=460, Evalue=1e-129,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=26.908150064683, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789246, Length=823, Percent_Identity=26.7314702308627, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1786478, Length=697, Percent_Identity=23.6728837876614, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=768, Percent_Identity=40.1041666666667, Blast_Score=509, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI32566215, Length=721, Percent_Identity=33.5644937586685, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17539860, Length=738, Percent_Identity=32.9268292682927, Blast_Score=345, Evalue=6e-95,
Organism=Drosophila melanogaster, GI17737937, Length=759, Percent_Identity=41.7654808959157, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24647193, Length=774, Percent_Identity=33.4625322997416, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24647199, Length=762, Percent_Identity=31.2335958005249, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24647201, Length=776, Percent_Identity=31.0567010309278, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24647195, Length=780, Percent_Identity=29.3589743589744, Blast_Score=286, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24647197, Length=770, Percent_Identity=29.6103896103896, Blast_Score=285, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2; PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.7 [H]

Molecular weight: Translated: 84645; Mature: 84645

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLGNTTEIKGAAHQDLKHESAIKQVQGRADYTDDILEPAGTLHAYLGVSTVAHANIRG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCC
MDLSRVRAAPGVVDVLTADDIPGVNDVSPTGKHDEPVFPTEKVEFHGQPLFAVIAESRDA
CCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCHHH
ARRAAELADVDYEVLPHALDAISARDAGLPMVTDPLKLERGDVESGLAEAPHRLQGRVVV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHCCHHHCCEEEE
GGQDHMYLEGHIAFAIPGEDDDVVVHCSTQHPSEAQHMVSHVLGVPSNAVVVNVRRMGGG
CCCCCEEEEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCC
FGGKESQMNLFCAFAALGAKKLNRPVKIRPDRDQDMTATGKRHDFVIDYDLGFDNEGRIE
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCHH
AVESQFAARCGYSSDLSGPVTDRALFHADNAYFYPNVRLTSCPQKTNTVSNTAFRGFGGP
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCCCEEECCCCCCCCCCCCCCCCCCCC
QGVVAAERMIEEIAYALGKDPLEVRKANFYGQPGDGRTLTPYHQEVEDNVIGRIVEELEE
CHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SSDYQARRAAIIAENTKGGIIRRGIALTPVKFGISFTATWYNQAGALIHIYNDGSIHLNH
CCCHHHHEEEEEEECCCCCEEECCEEECEEEECEEEEEEEECCCCCEEEEEECCEEEEEC
GGTEMGQGLNTKVAQVVAEAFQVDFDRIKITKTTTEKVPNTSATAASSGSDLNGMAALDA
CCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHH
CEQIKARLVKFAAESRGVAESAVRFGPNQIRIGEEVVDFAAFIREAYMARVHLSAAGFYK
HHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHEEEEECCCCC
TPKIHWDRAAGKGRPFYYYAYGASCSEVSIDTLTGEYRVERTDILHDVGRSLNPILDKGQ
CCCEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCEEEHHHHHHHHHHHHHCHHHCCCC
VEGAFIQGMGWLTTEELWWDKDGRLRTHAPSTYKIPLASDRPRSFNVKLADWSENREMTI
CCCEEEECCCCCEEHHHEECCCCCEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCEEE
KRSKAVGEPPFMLGISVLEALSMAVASVADYRECPRLEAPATPERVLMAVERLKAGG
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDLGNTTEIKGAAHQDLKHESAIKQVQGRADYTDDILEPAGTLHAYLGVSTVAHANIRG
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCC
MDLSRVRAAPGVVDVLTADDIPGVNDVSPTGKHDEPVFPTEKVEFHGQPLFAVIAESRDA
CCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCHHH
ARRAAELADVDYEVLPHALDAISARDAGLPMVTDPLKLERGDVESGLAEAPHRLQGRVVV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHCCHHHCCEEEE
GGQDHMYLEGHIAFAIPGEDDDVVVHCSTQHPSEAQHMVSHVLGVPSNAVVVNVRRMGGG
CCCCCEEEEEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCC
FGGKESQMNLFCAFAALGAKKLNRPVKIRPDRDQDMTATGKRHDFVIDYDLGFDNEGRIE
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCHH
AVESQFAARCGYSSDLSGPVTDRALFHADNAYFYPNVRLTSCPQKTNTVSNTAFRGFGGP
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEECCCCEEECCCCCCCCCCCCCCCCCCCC
QGVVAAERMIEEIAYALGKDPLEVRKANFYGQPGDGRTLTPYHQEVEDNVIGRIVEELEE
CHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SSDYQARRAAIIAENTKGGIIRRGIALTPVKFGISFTATWYNQAGALIHIYNDGSIHLNH
CCCHHHHEEEEEEECCCCCEEECCEEECEEEECEEEEEEEECCCCCEEEEEECCEEEEEC
GGTEMGQGLNTKVAQVVAEAFQVDFDRIKITKTTTEKVPNTSATAASSGSDLNGMAALDA
CCHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHH
CEQIKARLVKFAAESRGVAESAVRFGPNQIRIGEEVVDFAAFIREAYMARVHLSAAGFYK
HHHHHHHHHHHHHHCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHEEEEECCCCC
TPKIHWDRAAGKGRPFYYYAYGASCSEVSIDTLTGEYRVERTDILHDVGRSLNPILDKGQ
CCCEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCEEEHHHHHHHHHHHHHCHHHCCCC
VEGAFIQGMGWLTTEELWWDKDGRLRTHAPSTYKIPLASDRPRSFNVKLADWSENREMTI
CCCEEEECCCCCEEHHHEECCCCCEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCEEE
KRSKAVGEPPFMLGISVLEALSMAVASVADYRECPRLEAPATPERVLMAVERLKAGG
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8143744; 7502041; 8799115; 11713686 [H]