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The map label for this gene is proX [H]

Identifier: 99082441

GI number: 99082441

Start: 2738369

End: 2738899

Strand: Reverse

Name: proX [H]

Synonym: TM1040_2601

Alternate gene names: 99082441

Gene position: 2738899-2738369 (Counterclockwise)

Preceding gene: 99082442

Following gene: 99082439

Centisome position: 85.57

GC content: 60.45

Gene sequence:

>531_bases
ATGGACGCGACACATGCTGCATCAGAAGAAGGCTTGCCGATTTCTTGCGAGGACCTGTTGAGCCAGCTCAATTCGTGGGG
GATTTCCTATGTTCTGCACGAACACGCGCCGTTGCGCACCGTAGAGGATGCAAAGGCCGTCGAGGGGGCGCTGCTGCGCC
CGGGAGAGCAGGCGTTGCGATTGAAGAACCTCTACCTGCGTGACCGCAAGAAGCGCAATTACCTGGTGTCGCTGGAACAG
GACCGGGACGTGGACCTCAAGGCGCTCGGTGCAACACTGGGTGGTGGCGGGCTGTCGTTTGGCTCCGCGGATCGGCTAAT
GGAGTTTCTCGGGGTGCGGCCCGGAGCCGTGACACCGCTGGCGATGATCAACGGCGCGCCCAAGGGGGTGCGTTTCTTTA
TGGATGCACAAGCGCAGCATGCCGACAGTATCTATATGCATCCGCTTGTAAACACGCGCACCTTGGCGATGCCGCGTGCA
GACCTGATGGTGTTCTTTGAACGGATCGGCGTCACGCCCGAGTGGATCTGA

Upstream 100 bases:

>100_bases
GGCCGTGGCCTGAGGGGCGCGGGTTTGATATTGCCGAGCCCCTGAGACATCTGCCAAACAGCCGCAAGACTTACGCGCGC
TGTTTTGCAAAGGATCTCTT

Downstream 100 bases:

>100_bases
CCGCAGAGGATCAGCACGAGAGGCGTGGTTTGATTGCCCAACGGGCTGAGGGGTTGCGCTCCGCTTTGCGGATCGCCGGG
GGCAGGCCGCGCCTGCGGCG

Product: Ala-tRNA(Pro) hydrolase

Products: NA

Alternate protein names: Prolyl-tRNA deacylase proX [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MDATHAASEEGLPISCEDLLSQLNSWGISYVLHEHAPLRTVEDAKAVEGALLRPGEQALRLKNLYLRDRKKRNYLVSLEQ
DRDVDLKALGATLGGGGLSFGSADRLMEFLGVRPGAVTPLAMINGAPKGVRFFMDAQAQHADSIYMHPLVNTRTLAMPRA
DLMVFFERIGVTPEWI

Sequences:

>Translated_176_residues
MDATHAASEEGLPISCEDLLSQLNSWGISYVLHEHAPLRTVEDAKAVEGALLRPGEQALRLKNLYLRDRKKRNYLVSLEQ
DRDVDLKALGATLGGGGLSFGSADRLMEFLGVRPGAVTPLAMINGAPKGVRFFMDAQAQHADSIYMHPLVNTRTLAMPRA
DLMVFFERIGVTPEWI
>Mature_176_residues
MDATHAASEEGLPISCEDLLSQLNSWGISYVLHEHAPLRTVEDAKAVEGALLRPGEQALRLKNLYLRDRKKRNYLVSLEQ
DRDVDLKALGATLGGGGLSFGSADRLMEFLGVRPGAVTPLAMINGAPKGVRFFMDAQAQHADSIYMHPLVNTRTLAMPRA
DLMVFFERIGVTPEWI

Specific function: Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has weak activity on correctly charged tRNA(Ala), tRNA(Gly) as well as tRNA(Cys), tRNA(Met), tRNA(Pro), tRNA(Ser) and tRNA(Leu) [H]

COG id: COG3760

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prolyl-tRNA editing family. ProX subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007214 [H]

Pfam domain/function: PF04073 YbaK [H]

EC number: NA

Molecular weight: Translated: 19388; Mature: 19388

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATHAASEEGLPISCEDLLSQLNSWGISYVLHEHAPLRTVEDAKAVEGALLRPGEQALR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHH
LKNLYLRDRKKRNYLVSLEQDRDVDLKALGATLGGGGLSFGSADRLMEFLGVRPGAVTPL
HHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
AMINGAPKGVRFFMDAQAQHADSIYMHPLVNTRTLAMPRADLMVFFERIGVTPEWI
HHHCCCCCCEEEEECCCCCCCCCEEECCCCCCEEECCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDATHAASEEGLPISCEDLLSQLNSWGISYVLHEHAPLRTVEDAKAVEGALLRPGEQALR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHH
LKNLYLRDRKKRNYLVSLEQDRDVDLKALGATLGGGGLSFGSADRLMEFLGVRPGAVTPL
HHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHH
AMINGAPKGVRFFMDAQAQHADSIYMHPLVNTRTLAMPRADLMVFFERIGVTPEWI
HHHCCCCCCEEEEECCCCCCCCCEEECCCCCCEEECCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10085076 [H]