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The map label for this gene is pdxJ [H]

Identifier: 99082403

GI number: 99082403

Start: 2705435

End: 2706193

Strand: Reverse

Name: pdxJ [H]

Synonym: TM1040_2563

Alternate gene names: 99082403

Gene position: 2706193-2705435 (Counterclockwise)

Preceding gene: 99082404

Following gene: 99082402

Centisome position: 84.54

GC content: 61.66

Gene sequence:

>759_bases
ATGTCTACCAACACTCTGCGCCTTGGCGTCAATATCGACCATGTCGCGACCGTGAGAAACGCGCGTGGCGGTGCCTATCC
AGACCCGATCCGCGCGGCGAAATTGGCCGAAGAGGCCGGAGCCGATGGCATCACGGCGCATCTGCGCGAAGACCGCCGCC
ACATCGTTGATGCGGACATCGACGGCCTTATGGCTGCGCTGACGGTGCCGCTCAATTTTGAGATGGCCGCAACCGAGGAA
ATGCAAAAGATTGCCCTGCGTCACAAACCACATGCGGTCTGCATCGTGCCGGAAAAGCGCGAGGAACGCACAACCGAAGG
CGGGCTTGATGTGGTGCGCGACGAAAGCCGGCTGGCTGCCTGTATTGCGCCGCTGCGAGAGGCCGGAAGCCGGGTTTCTA
TTTTCATCGCTGCGGATCAGAAACAGATCGAAGCCGCCCATCGCATCGGTGCCGAGGTGATCGAGCTGCACACCGGAGCC
TATTGCGACCACCACGCCGAGGGCGATTTTGCTGCCCGCGACGCTGAGTTGGCAGCGCTTGGCGAGATGGCCACCTACGC
ACATTCCTTGGGGCTTGAAGTTCACGCGGGGCATGGCCTCACCTACGAGACGGTTGCCCCTATCGCCGCCTTTCCCGAGG
TGCGGGAGCTCAATATCGGGCATTTTCTGATCGGCGAGGCGATTTTTCGCGGCCTTTCTCCCGCGATTGGTGAAATGCGC
CGCCTGATGGATGCGGCACGCTCTGGAGCTGACGCGTGA

Upstream 100 bases:

>100_bases
AGATGGCGGAGAATTGTATCACTTCGCCCCTTGTGCCTTGCCTCTTTGGCCTTCACCGCTAGGGTCTGCTGCAACAGACA
CCCACCAAAGAGACCCTCTC

Downstream 100 bases:

>100_bases
AACTGGGTCGGTTTGCCATTGTCTACCTCGGGATCATGGTTGCCCTGATGGTGCTGATCTTGTTGGTGCAGGCGATTTTT
CGCTTTGACATCTCGAATGC

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSTNTLRLGVNIDHVATVRNARGGAYPDPIRAAKLAEEAGADGITAHLREDRRHIVDADIDGLMAALTVPLNFEMAATEE
MQKIALRHKPHAVCIVPEKREERTTEGGLDVVRDESRLAACIAPLREAGSRVSIFIAADQKQIEAAHRIGAEVIELHTGA
YCDHHAEGDFAARDAELAALGEMATYAHSLGLEVHAGHGLTYETVAPIAAFPEVRELNIGHFLIGEAIFRGLSPAIGEMR
RLMDAARSGADA

Sequences:

>Translated_252_residues
MSTNTLRLGVNIDHVATVRNARGGAYPDPIRAAKLAEEAGADGITAHLREDRRHIVDADIDGLMAALTVPLNFEMAATEE
MQKIALRHKPHAVCIVPEKREERTTEGGLDVVRDESRLAACIAPLREAGSRVSIFIAADQKQIEAAHRIGAEVIELHTGA
YCDHHAEGDFAARDAELAALGEMATYAHSLGLEVHAGHGLTYETVAPIAAFPEVRELNIGHFLIGEAIFRGLSPAIGEMR
RLMDAARSGADA
>Mature_251_residues
STNTLRLGVNIDHVATVRNARGGAYPDPIRAAKLAEEAGADGITAHLREDRRHIVDADIDGLMAALTVPLNFEMAATEEM
QKIALRHKPHAVCIVPEKREERTTEGGLDVVRDESRLAACIAPLREAGSRVSIFIAADQKQIEAAHRIGAEVIELHTGAY
CDHHAEGDFAARDAELAALGEMATYAHSLGLEVHAGHGLTYETVAPIAAFPEVRELNIGHFLIGEAIFRGLSPAIGEMRR
LMDAARSGADA

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=242, Percent_Identity=57.0247933884297, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 27089; Mature: 26958

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNTLRLGVNIDHVATVRNARGGAYPDPIRAAKLAEEAGADGITAHLREDRRHIVDADI
CCCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
DGLMAALTVPLNFEMAATEEMQKIALRHKPHAVCIVPEKREERTTEGGLDVVRDESRLAA
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCCEEECHHHHHH
CIAPLREAGSRVSIFIAADQKQIEAAHRIGAEVIELHTGAYCDHHAEGDFAARDAELAAL
HHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHH
GEMATYAHSLGLEVHAGHGLTYETVAPIAAFPEVRELNIGHFLIGEAIFRGLSPAIGEMR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHH
RLMDAARSGADA
HHHHHHHCCCCC
>Mature Secondary Structure 
STNTLRLGVNIDHVATVRNARGGAYPDPIRAAKLAEEAGADGITAHLREDRRHIVDADI
CCCEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCH
DGLMAALTVPLNFEMAATEEMQKIALRHKPHAVCIVPEKREERTTEGGLDVVRDESRLAA
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCCEEECHHHHHH
CIAPLREAGSRVSIFIAADQKQIEAAHRIGAEVIELHTGAYCDHHAEGDFAARDAELAAL
HHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCHHHHHH
GEMATYAHSLGLEVHAGHGLTYETVAPIAAFPEVRELNIGHFLIGEAIFRGLSPAIGEMR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCHHHHHHH
RLMDAARSGADA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA