Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 99082357

GI number: 99082357

Start: 2657069

End: 2658073

Strand: Reverse

Name: qor [H]

Synonym: TM1040_2517

Alternate gene names: 99082357

Gene position: 2658073-2657069 (Counterclockwise)

Preceding gene: 99082358

Following gene: 99082356

Centisome position: 83.04

GC content: 63.38

Gene sequence:

>1005_bases
ATGACGTTAGAACTCCCGCAGACAATGCGCGCGATTGAAATCTCGGAATTTGGCGCGCCGAATGTGCTCAAGCTTGTGGA
GCGCCCGGTGCCGTCCGCTGGCTATGGTCAGGTGGTGATCCGCGTTGCATATGCCGGAGTGAACCGGCCGGACGCCTTGC
AGCGTGCCGGCGCCTACGCGCCGCCGAAAGGCGCGAGCGACCTACCTGGGCTGGAGGCCTCAGGCGAGATTGTCGCGCTG
GGCGAAGGTGTAACCGGCTGGAATCTTGGTGATCGCGTCTGCGCCTTGCTGCCCGGCGGCGGTTACGCGGACTATGTCGC
TACGCCAGCAGCCCATTGCCTGCCGGTTCCTAAAGGGCTGAGCCTCAAGGAAGCCGCCTGCCTGCCCGAGACCTGTTTCA
CGGTTTGGTCGAATGTCGTCACGCGCGGCGGCCTTCGCGCCGGAGAGCGTTTCCTTGTGCATGGCGGGTCCTCGGGAATT
GGCACCACCGCCATTCAGTTGGCGTCTGCGCTGGGGGCGCGGGTCTATGCCACCGCGGGGTCGGACGACAAATGCGCTGC
CTGCGTCGGACTCGGGGCAGATGTCGCGATCAATTATCGCGATGAAGATTTTGTCGAGATCCTCAGGGCAGACGGGGGCG
CACATCTTATTCTGGACATGGTGGGTGGGGACTACATCCCCCGCAACATTAAGGCGCTCGCGGATGATGGGCGGCTGGTC
CACATTGCCTTTCTGCAAGGCCCAAAGGCGGAGCTGAATTTTGCGCAGATCATGGCGCGCCGTCTCACGGTCACGGGATC
AACTCTCCGTCCCCAAAGCGACCTCGCCAAGGCGCGCATCGCCCGGGATCTGCTGGAGGCCGTTTGGCCGCTGATCGAGG
CTGGAAAACTGCGCCCCGTGATGGACTCGACCTTCGCATTGGCGGAGGCCGCCATTGCACATGCGCGCATGGAGGGATCG
ACCCATATCGGAAAAATCGTGCTGGAGGTCGCAGGCGCCGACTGA

Upstream 100 bases:

>100_bases
GGGTGGCCCGCGCGCGGGGCGCGGCGAGAGTTTGCATGGCTTGGCCGATTGAAGCGGGGATGCTAGGTCTCTGGGCAACA
GATAGCAGAGGACCGTTCCG

Downstream 100 bases:

>100_bases
CGCGCTGGAGATACAGCTGCTGGCGTTTATCCGATCATTTGTCGATTTTTTATCGGCGAGAGGGGGCAAGTCCCTAGCCA
AGAGCATTCTTCTTGCTTCA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTLELPQTMRAIEISEFGAPNVLKLVERPVPSAGYGQVVIRVAYAGVNRPDALQRAGAYAPPKGASDLPGLEASGEIVAL
GEGVTGWNLGDRVCALLPGGGYADYVATPAAHCLPVPKGLSLKEAACLPETCFTVWSNVVTRGGLRAGERFLVHGGSSGI
GTTAIQLASALGARVYATAGSDDKCAACVGLGADVAINYRDEDFVEILRADGGAHLILDMVGGDYIPRNIKALADDGRLV
HIAFLQGPKAELNFAQIMARRLTVTGSTLRPQSDLAKARIARDLLEAVWPLIEAGKLRPVMDSTFALAEAAIAHARMEGS
THIGKIVLEVAGAD

Sequences:

>Translated_334_residues
MTLELPQTMRAIEISEFGAPNVLKLVERPVPSAGYGQVVIRVAYAGVNRPDALQRAGAYAPPKGASDLPGLEASGEIVAL
GEGVTGWNLGDRVCALLPGGGYADYVATPAAHCLPVPKGLSLKEAACLPETCFTVWSNVVTRGGLRAGERFLVHGGSSGI
GTTAIQLASALGARVYATAGSDDKCAACVGLGADVAINYRDEDFVEILRADGGAHLILDMVGGDYIPRNIKALADDGRLV
HIAFLQGPKAELNFAQIMARRLTVTGSTLRPQSDLAKARIARDLLEAVWPLIEAGKLRPVMDSTFALAEAAIAHARMEGS
THIGKIVLEVAGAD
>Mature_333_residues
TLELPQTMRAIEISEFGAPNVLKLVERPVPSAGYGQVVIRVAYAGVNRPDALQRAGAYAPPKGASDLPGLEASGEIVALG
EGVTGWNLGDRVCALLPGGGYADYVATPAAHCLPVPKGLSLKEAACLPETCFTVWSNVVTRGGLRAGERFLVHGGSSGIG
TTAIQLASALGARVYATAGSDDKCAACVGLGADVAINYRDEDFVEILRADGGAHLILDMVGGDYIPRNIKALADDGRLVH
IAFLQGPKAELNFAQIMARRLTVTGSTLRPQSDLAKARIARDLLEAVWPLIEAGKLRPVMDSTFALAEAAIAHARMEGST
HIGKIVLEVAGAD

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=39.1566265060241, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=39.1566265060241, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=29.0909090909091, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=29.0909090909091, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=27.906976744186, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=28.4403669724771, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI28557745, Length=266, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI18379349, Length=342, Percent_Identity=26.9005847953216, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41872631, Length=307, Percent_Identity=30.2931596091205, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI47519420, Length=354, Percent_Identity=28.2485875706215, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=324, Percent_Identity=28.7037037037037, Blast_Score=100, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17507255, Length=328, Percent_Identity=28.9634146341463, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI212642053, Length=336, Percent_Identity=26.4880952380952, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=366, Percent_Identity=25.4098360655738, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988145, Length=307, Percent_Identity=20.5211726384365, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=27.9411764705882, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323961, Length=319, Percent_Identity=26.0188087774295, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=361, Percent_Identity=23.2686980609418, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=351, Percent_Identity=22.5071225071225, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581345, Length=321, Percent_Identity=27.1028037383178, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920632, Length=298, Percent_Identity=26.8456375838926, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221330659, Length=298, Percent_Identity=26.8456375838926, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24581339, Length=365, Percent_Identity=27.6712328767123, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581341, Length=365, Percent_Identity=27.6712328767123, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34858; Mature: 34727

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLELPQTMRAIEISEFGAPNVLKLVERPVPSAGYGQVVIRVAYAGVNRPDALQRAGAYA
CCCCCCHHHHHEEHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
PPKGASDLPGLEASGEIVALGEGVTGWNLGDRVCALLPGGGYADYVATPAAHCLPVPKGL
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHCCHHHHCCCCCCC
SLKEAACLPETCFTVWSNVVTRGGLRAGERFLVHGGSSGIGTTAIQLASALGARVYATAG
CHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SDDKCAACVGLGADVAINYRDEDFVEILRADGGAHLILDMVGGDYIPRNIKALADDGRLV
CCCCCEEEEECCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCEE
HIAFLQGPKAELNFAQIMARRLTVTGSTLRPQSDLAKARIARDLLEAVWPLIEAGKLRPV
EEEEECCCCCCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MDSTFALAEAAIAHARMEGSTHIGKIVLEVAGAD
HHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCC
>Mature Secondary Structure 
TLELPQTMRAIEISEFGAPNVLKLVERPVPSAGYGQVVIRVAYAGVNRPDALQRAGAYA
CCCCCHHHHHEEHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCC
PPKGASDLPGLEASGEIVALGEGVTGWNLGDRVCALLPGGGYADYVATPAAHCLPVPKGL
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHCCHHHHCCCCCCC
SLKEAACLPETCFTVWSNVVTRGGLRAGERFLVHGGSSGIGTTAIQLASALGARVYATAG
CHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SDDKCAACVGLGADVAINYRDEDFVEILRADGGAHLILDMVGGDYIPRNIKALADDGRLV
CCCCCEEEEECCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCEE
HIAFLQGPKAELNFAQIMARRLTVTGSTLRPQSDLAKARIARDLLEAVWPLIEAGKLRPV
EEEEECCCCCCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
MDSTFALAEAAIAHARMEGSTHIGKIVLEVAGAD
HHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]