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The map label for this gene is ctaC [H]

Identifier: 99082176

GI number: 99082176

Start: 2455186

End: 2456100

Strand: Reverse

Name: ctaC [H]

Synonym: TM1040_2336

Alternate gene names: 99082176

Gene position: 2456100-2455186 (Counterclockwise)

Preceding gene: 99082182

Following gene: 99082175

Centisome position: 76.73

GC content: 57.6

Gene sequence:

>915_bases
ATGAAGAATGCTTTGACGCTTTCGGGCTTTATCGCCGCCCTTTCTAGCCTTCCAGCCATGGCGCAAGAAGGTCTGGAAAC
CATTGGTAAGCCGACGGACGGCAACCTCGGTTTTCAGCCGGCGGCGTCCGAATTGGCAGAGGGCATTCACAAGCTCGACT
ACATGATTCTCATCATCATCACCGCGATCTGTGTGTTCGTGGGTGGTCTGCTGCTTTACGCAATTGTGCGTTTCAACCGT
CGCGCCAACCCCAAGGCAGCGAGCTTCACGCACAACACCCCGATCGAGATCGCTTGGACCGTGGTGCCGATCCTTATCCT
GATCGTAATTGGCTCCTTCTCGCTGCCAGAACTGTTCCGCCAGCAGGAAATCCCCGAGGGCGACGTGACCATCAAGGTGA
CCGGCTACCAGTGGTACTGGGGCTACGAGTATGTGGATCACGACTTTGCCTTTGACAGCTATCTCATCGGCCACCCGGCG
ACGCTGGACGAATCCACGCGCCCTGCCGACGCGGATGTGACGCCTTTCGTCTATGACGAAGCGATGAAGCTGAAGCTCGA
AGAAGCGGGCTACGCAGGCGACGAATTCCTTCTGGCGACCAACACTGCGGTTGTTGTTCCGGTGAACAAAACCATCGTGA
TGCAGGTAACGGCTGCTGACGTGATCCACTCCTGGGCGCTGCCGTCGTTCGGCGTGAAGCAGGATGGCATCCCCGGCCGC
CTTGCGGAACTGTGGTTCAAGCCAACCAAAGAAGGCGTCTACTTTGGCCAATGTTCCGAGCTTTGCGGCAAGGACCACGC
TTATATGCCGATCACCGTCAAAGTGGTCAGCGAAGAAGCCTATCAGGAATGGCTGAACGGCGCGATCGAGGAATACGCGG
GTCTGCCGCAGCCCTACGACGTCGCTTCCAAGTGA

Upstream 100 bases:

>100_bases
ATATGATTTTTAACGGCAACAAAGACAACGGGCGCGGTAGAGTTTTTCGAACGATTCCGCGATCCCAACCCATGCAACGA
TCAAGCGATCAGGAAACGAC

Downstream 100 bases:

>100_bases
TCTGACTGGACCCTCGGCGCGCGTCCGCTATCTGCTGAGAGAGCCGCGTGCTGACGGATGAGACCAAGAGCGACCACGCG
CTTTGCGTGGTCGTCCATGA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKNALTLSGFIAALSSLPAMAQEGLETIGKPTDGNLGFQPAASELAEGIHKLDYMILIIITAICVFVGGLLLYAIVRFNR
RANPKAASFTHNTPIEIAWTVVPILILIVIGSFSLPELFRQQEIPEGDVTIKVTGYQWYWGYEYVDHDFAFDSYLIGHPA
TLDESTRPADADVTPFVYDEAMKLKLEEAGYAGDEFLLATNTAVVVPVNKTIVMQVTAADVIHSWALPSFGVKQDGIPGR
LAELWFKPTKEGVYFGQCSELCGKDHAYMPITVKVVSEEAYQEWLNGAIEEYAGLPQPYDVASK

Sequences:

>Translated_304_residues
MKNALTLSGFIAALSSLPAMAQEGLETIGKPTDGNLGFQPAASELAEGIHKLDYMILIIITAICVFVGGLLLYAIVRFNR
RANPKAASFTHNTPIEIAWTVVPILILIVIGSFSLPELFRQQEIPEGDVTIKVTGYQWYWGYEYVDHDFAFDSYLIGHPA
TLDESTRPADADVTPFVYDEAMKLKLEEAGYAGDEFLLATNTAVVVPVNKTIVMQVTAADVIHSWALPSFGVKQDGIPGR
LAELWFKPTKEGVYFGQCSELCGKDHAYMPITVKVVSEEAYQEWLNGAIEEYAGLPQPYDVASK
>Mature_304_residues
MKNALTLSGFIAALSSLPAMAQEGLETIGKPTDGNLGFQPAASELAEGIHKLDYMILIIITAICVFVGGLLLYAIVRFNR
RANPKAASFTHNTPIEIAWTVVPILILIVIGSFSLPELFRQQEIPEGDVTIKVTGYQWYWGYEYVDHDFAFDSYLIGHPA
TLDESTRPADADVTPFVYDEAMKLKLEEAGYAGDEFLLATNTAVVVPVNKTIVMQVTAADVIHSWALPSFGVKQDGIPGR
LAELWFKPTKEGVYFGQCSELCGKDHAYMPITVKVVSEEAYQEWLNGAIEEYAGLPQPYDVASK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=250, Percent_Identity=33.2, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6226540, Length=257, Percent_Identity=38.9105058365759, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33417; Mature: 33417

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNALTLSGFIAALSSLPAMAQEGLETIGKPTDGNLGFQPAASELAEGIHKLDYMILIII
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TAICVFVGGLLLYAIVRFNRRANPKAASFTHNTPIEIAWTVVPILILIVIGSFSLPELFR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
QQEIPEGDVTIKVTGYQWYWGYEYVDHDFAFDSYLIGHPATLDESTRPADADVTPFVYDE
HHCCCCCCEEEEEEEEEEEECCEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHH
AMKLKLEEAGYAGDEFLLATNTAVVVPVNKTIVMQVTAADVIHSWALPSFGVKQDGIPGR
HHHEEEHHCCCCCCEEEEEECCEEEEECCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCHH
LAELWFKPTKEGVYFGQCSELCGKDHAYMPITVKVVSEEAYQEWLNGAIEEYAGLPQPYD
HHHHHCCCCCCCEEEECHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCC
VASK
CCCC
>Mature Secondary Structure
MKNALTLSGFIAALSSLPAMAQEGLETIGKPTDGNLGFQPAASELAEGIHKLDYMILIII
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TAICVFVGGLLLYAIVRFNRRANPKAASFTHNTPIEIAWTVVPILILIVIGSFSLPELFR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
QQEIPEGDVTIKVTGYQWYWGYEYVDHDFAFDSYLIGHPATLDESTRPADADVTPFVYDE
HHCCCCCCEEEEEEEEEEEECCEECCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHH
AMKLKLEEAGYAGDEFLLATNTAVVVPVNKTIVMQVTAADVIHSWALPSFGVKQDGIPGR
HHHEEEHHCCCCCCEEEEEECCEEEEECCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCHH
LAELWFKPTKEGVYFGQCSELCGKDHAYMPITVKVVSEEAYQEWLNGAIEEYAGLPQPYD
HHHHHCCCCCCCEEEECHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCC
VASK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]