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The map label for this gene is 99082140

Identifier: 99082140

GI number: 99082140

Start: 2418908

End: 2420032

Strand: Reverse

Name: 99082140

Synonym: TM1040_2300

Alternate gene names: NA

Gene position: 2420032-2418908 (Counterclockwise)

Preceding gene: 99082141

Following gene: 99082136

Centisome position: 75.6

GC content: 59.64

Gene sequence:

>1125_bases
ATGGCCCTCTTGGAGACAGTCGACCCCGATGGTCTGGATGAGTTCTCGGTGGTCTTCACCGACCGCTCCCTCAATCACAT
GTCAAAGGAATTTCAGCAGGTGATGCTGGACATCAACGCCATGCTGAAAGAGGTCTACAAGGCCGACGCCACCGCATTGG
TGCCCGGCGGCGGCACCTTCGCAATGGAGGCGGTGGCCCGCCAGTTCGCCCGCGATCAGGATGCGTTGGTGGTGCGTAAC
GGCTGGTTTTCCTACCGCTGGAGTCAAATTTTTGAATCCGGCGGCCTCACAAAATCCGCAACCGTTCTCAAGGCGCGTCA
GATTGGAAATGGGGCGCAGTCTCCTTTTGCACCCGCACCCATTGAAGACGTCACCAAGGCAATCCTGGAGCAAAAGCCCT
CCATCGTCTTTGCCCCGCATGTGGAAACGTCTGCGGGCGTGATCCTGCCCGATGACTATGTGACCCGGATGGCGACCGCC
GCGCATGAGGTCGGCGCATTGATGGTGCTCGATTGCATCGCCTCTGGCTGCGCCTGGGTCGATATGAGGGCTACAGGCGT
CGACGTGCTGATCTCGGCCCCGCAAAAGGGCTGGAGCGCCTCCCCTTCAGCGGGTCTGGTGATGCTCTCAAAACGCGCGC
TTGCGCGTCTGGAGGAGACCACCTCAGACAGTTTCGCCATCGACCTCAAGAAATGGCGTGCGATCATGCAGGCCTATGAG
GACGGCGGCCACGCCTATCACGCCACCATGCCGACGGACGCGCTGCGTCAATTCCGGGACACGATGGCGGAAACCAAGGC
TTATGGCTTTAAGCGCCTGCGCGAGGCCCAGTGGAAACTCGGCAATGGTGTGCGCGAAATGCTTGCCAAAAAGGGCGTCA
CCTCCGTCGCCGCCGAGGGCTTTGGCGCGCCGGGTGTGGTCGTAAGCTACACTGATGATCCCCAGATCCAGAATGGCAAG
AAATTCTCCGATCAAGGCATGCAGATTGCTGCGGGCGTGCCGCTTGCGGTGGACGAACCCGATGGCTTCATGACCTTCCG
CCTTGGGCTATTTGGTCTTGATAAACTTTATGATGTGAACGGCACGCTCTCGCGGCTTAAAACCGTGCTCGACCAGCTGC
TCTGA

Upstream 100 bases:

>100_bases
ACAAGAGCTGTAGCCACGTGGCGCTTGAGCCAGCAGAGCGGCTCTGCCATGACAGGGGCAACCGGCCTCAGCCAACACAA
TTGCAGCAAGGAGATTTCAC

Downstream 100 bases:

>100_bases
CAGCGCTTCATCTTTTCAAAAATATCTCCGCCGGAGGCGCGGGCCTGCCCTTTGGGGCAGGCCCGTTTTCTATCGCACGC
CAAGCCCCATCTGCATCAGC

Product: aminotransferase, class V

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MALLETVDPDGLDEFSVVFTDRSLNHMSKEFQQVMLDINAMLKEVYKADATALVPGGGTFAMEAVARQFARDQDALVVRN
GWFSYRWSQIFESGGLTKSATVLKARQIGNGAQSPFAPAPIEDVTKAILEQKPSIVFAPHVETSAGVILPDDYVTRMATA
AHEVGALMVLDCIASGCAWVDMRATGVDVLISAPQKGWSASPSAGLVMLSKRALARLEETTSDSFAIDLKKWRAIMQAYE
DGGHAYHATMPTDALRQFRDTMAETKAYGFKRLREAQWKLGNGVREMLAKKGVTSVAAEGFGAPGVVVSYTDDPQIQNGK
KFSDQGMQIAAGVPLAVDEPDGFMTFRLGLFGLDKLYDVNGTLSRLKTVLDQLL

Sequences:

>Translated_374_residues
MALLETVDPDGLDEFSVVFTDRSLNHMSKEFQQVMLDINAMLKEVYKADATALVPGGGTFAMEAVARQFARDQDALVVRN
GWFSYRWSQIFESGGLTKSATVLKARQIGNGAQSPFAPAPIEDVTKAILEQKPSIVFAPHVETSAGVILPDDYVTRMATA
AHEVGALMVLDCIASGCAWVDMRATGVDVLISAPQKGWSASPSAGLVMLSKRALARLEETTSDSFAIDLKKWRAIMQAYE
DGGHAYHATMPTDALRQFRDTMAETKAYGFKRLREAQWKLGNGVREMLAKKGVTSVAAEGFGAPGVVVSYTDDPQIQNGK
KFSDQGMQIAAGVPLAVDEPDGFMTFRLGLFGLDKLYDVNGTLSRLKTVLDQLL
>Mature_373_residues
ALLETVDPDGLDEFSVVFTDRSLNHMSKEFQQVMLDINAMLKEVYKADATALVPGGGTFAMEAVARQFARDQDALVVRNG
WFSYRWSQIFESGGLTKSATVLKARQIGNGAQSPFAPAPIEDVTKAILEQKPSIVFAPHVETSAGVILPDDYVTRMATAA
HEVGALMVLDCIASGCAWVDMRATGVDVLISAPQKGWSASPSAGLVMLSKRALARLEETTSDSFAIDLKKWRAIMQAYED
GGHAYHATMPTDALRQFRDTMAETKAYGFKRLREAQWKLGNGVREMLAKKGVTSVAAEGFGAPGVVVSYTDDPQIQNGKK
FSDQGMQIAAGVPLAVDEPDGFMTFRLGLFGLDKLYDVNGTLSRLKTVLDQLL

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=259, Percent_Identity=26.6409266409266, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536281, Length=366, Percent_Identity=25.6830601092896, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321079, Length=371, Percent_Identity=25.3369272237197, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: NA

Molecular weight: Translated: 40613; Mature: 40482

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLETVDPDGLDEFSVVFTDRSLNHMSKEFQQVMLDINAMLKEVYKADATALVPGGGTF
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHH
AMEAVARQFARDQDALVVRNGWFSYRWSQIFESGGLTKSATVLKARQIGNGAQSPFAPAP
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC
IEDVTKAILEQKPSIVFAPHVETSAGVILPDDYVTRMATAAHEVGALMVLDCIASGCAWV
HHHHHHHHHHCCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DMRATGVDVLISAPQKGWSASPSAGLVMLSKRALARLEETTSDSFAIDLKKWRAIMQAYE
EEECCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
DGGHAYHATMPTDALRQFRDTMAETKAYGFKRLREAQWKLGNGVREMLAKKGVTSVAAEG
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
FGAPGVVVSYTDDPQIQNGKKFSDQGMQIAAGVPLAVDEPDGFMTFRLGLFGLDKLYDVN
CCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEHHHHHHHHHHCCC
GTLSRLKTVLDQLL
CHHHHHHHHHHHHC
>Mature Secondary Structure 
ALLETVDPDGLDEFSVVFTDRSLNHMSKEFQQVMLDINAMLKEVYKADATALVPGGGTF
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHH
AMEAVARQFARDQDALVVRNGWFSYRWSQIFESGGLTKSATVLKARQIGNGAQSPFAPAP
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCC
IEDVTKAILEQKPSIVFAPHVETSAGVILPDDYVTRMATAAHEVGALMVLDCIASGCAWV
HHHHHHHHHHCCCCEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DMRATGVDVLISAPQKGWSASPSAGLVMLSKRALARLEETTSDSFAIDLKKWRAIMQAYE
EEECCCEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
DGGHAYHATMPTDALRQFRDTMAETKAYGFKRLREAQWKLGNGVREMLAKKGVTSVAAEG
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
FGAPGVVVSYTDDPQIQNGKKFSDQGMQIAAGVPLAVDEPDGFMTFRLGLFGLDKLYDVN
CCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCEEEECCCCEEEEEHHHHHHHHHHCCC
GTLSRLKTVLDQLL
CHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]