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The map label for this gene is dadA [H]

Identifier: 99082117

GI number: 99082117

Start: 2392715

End: 2394016

Strand: Reverse

Name: dadA [H]

Synonym: TM1040_2277

Alternate gene names: 99082117

Gene position: 2394016-2392715 (Counterclockwise)

Preceding gene: 99082118

Following gene: 99082115

Centisome position: 74.79

GC content: 65.36

Gene sequence:

>1302_bases
ATGCCCGGACCTCAGCTGCCTCACTTCAATTCGGACCGCGTGCTGCCCAAAGCGGTTGATGTCGTCATCATCGGTGGCGG
TATCGTTGGTGCATCGACCGCGCTGGAGCTCGCAGAGCGGGGCCATTCCGTGCTCCTGTGCGAGAAAGGCCAGATCGCGG
GGGAGCAGAGCTCGCGCAACTGGGGCTGGGTTCGCATGTCCCAGCGCGATCCCCGCGAAATGGAACTGATGACCCACTCC
CAGCGCATCTGGGAAGGTCTGGATATGCGTACAGGCTACGCCACCGGCTATACCAAATGCGGCATCATGTTCACGGCCCA
CACCCGCAAACGCGAGGCGGAGCTCTCGGCGTGGTCAGAGCATCTGAAGGCGATTGGTGGCGAGGGGCACATGTTGCGCG
GCGAGTCACTGGAACAGCTGACGCCGGGCTATGGTCACCGAATCCGCGCCGGGTTCTACACCCCACAGGATGGCTGCGCC
GAGCCGCAGATGGCCACGCATGCAATCGCTTCCGCTGCGCGGGATAAGGGCGCGGTGGTCATCACCGGCTGCGCGGTGCG
ACGGCTGGATGTGGAGGCGGGGCGCATCCGGGGGGTCATCACCGAAAAGGGCCGCGTCAACGCCACCGCCGTGGTGGTGG
CAGGCGGTGCGTGGTCACGCTTGTTCCTGCGCAACGAGGGCCTGTTCCTGCCCCAGCTCAAGGTCCTCAACTCCGTGATG
CGCCTCTCCCCGGTCAAGGGTGTGCCGGAAACGGCACTCTGGGCGGCTGGTTTTGGCCTGCGCAAACGTATGGATGGGGG
CTACACGGTGGCCTCGGGCGGCGAGAACACCTTTGACATCGTGCCCGACACCTTTCGGATCGGTCATCGCTTTATCCCGG
CCTTTCTGCGTGATGTGACCGCGCTGCGCTTTCGCGTCTCAGACCGCTGGCGCATCGAGAGCGCCGAGGCCCGCCCCTGG
AGCGGTCAGGATCGCTCTCCGTTTGAAGAGACCCGCGTGCTGGACCCGCAACCTTCGCAAAAAGCGCTGCGTCGCGGTCT
TGCGGCGGTTCGAGATGCCTTCCCGGCGCTGGAAAAGGCCGATGTGACCCAAAGCTGGGGCGGGCTGATCGACGTGACCC
CGGACGAGATCCCGGTGATTTCCGAAGTGATCTCCCGTCCGGGGCTGTTTGTGTCCACCGGCTACAGCGGACATGGCTTT
GGCCTTGGCCCCGGGGCCGGTCGGTTGACGGCGGATCTGGTGACGGGGGACGCGCCCATCGTGGATCCGCGCCCCTTCCG
CCTCAGTCGTTTTGGCGCTTAG

Upstream 100 bases:

>100_bases
GGCCGTGATTGAGGCCCCGAGAACACAGGCTGCGGGAACCGGTCAAATGAGCTTCATGCGCGGCTGGACCCGCTGTTTGA
CACCGGACTAGAACGGGCCC

Downstream 100 bases:

>100_bases
CCCATCATCTGATAGCTGACCGGCACAAAACGGAACCCTTCGCCGCGCCGCTCGACATAGCCGGCGGCAGGGAAGGGCAT
GTGATAGCCGATCATTGGCG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MPGPQLPHFNSDRVLPKAVDVVIIGGGIVGASTALELAERGHSVLLCEKGQIAGEQSSRNWGWVRMSQRDPREMELMTHS
QRIWEGLDMRTGYATGYTKCGIMFTAHTRKREAELSAWSEHLKAIGGEGHMLRGESLEQLTPGYGHRIRAGFYTPQDGCA
EPQMATHAIASAARDKGAVVITGCAVRRLDVEAGRIRGVITEKGRVNATAVVVAGGAWSRLFLRNEGLFLPQLKVLNSVM
RLSPVKGVPETALWAAGFGLRKRMDGGYTVASGGENTFDIVPDTFRIGHRFIPAFLRDVTALRFRVSDRWRIESAEARPW
SGQDRSPFEETRVLDPQPSQKALRRGLAAVRDAFPALEKADVTQSWGGLIDVTPDEIPVISEVISRPGLFVSTGYSGHGF
GLGPGAGRLTADLVTGDAPIVDPRPFRLSRFGA

Sequences:

>Translated_433_residues
MPGPQLPHFNSDRVLPKAVDVVIIGGGIVGASTALELAERGHSVLLCEKGQIAGEQSSRNWGWVRMSQRDPREMELMTHS
QRIWEGLDMRTGYATGYTKCGIMFTAHTRKREAELSAWSEHLKAIGGEGHMLRGESLEQLTPGYGHRIRAGFYTPQDGCA
EPQMATHAIASAARDKGAVVITGCAVRRLDVEAGRIRGVITEKGRVNATAVVVAGGAWSRLFLRNEGLFLPQLKVLNSVM
RLSPVKGVPETALWAAGFGLRKRMDGGYTVASGGENTFDIVPDTFRIGHRFIPAFLRDVTALRFRVSDRWRIESAEARPW
SGQDRSPFEETRVLDPQPSQKALRRGLAAVRDAFPALEKADVTQSWGGLIDVTPDEIPVISEVISRPGLFVSTGYSGHGF
GLGPGAGRLTADLVTGDAPIVDPRPFRLSRFGA
>Mature_432_residues
PGPQLPHFNSDRVLPKAVDVVIIGGGIVGASTALELAERGHSVLLCEKGQIAGEQSSRNWGWVRMSQRDPREMELMTHSQ
RIWEGLDMRTGYATGYTKCGIMFTAHTRKREAELSAWSEHLKAIGGEGHMLRGESLEQLTPGYGHRIRAGFYTPQDGCAE
PQMATHAIASAARDKGAVVITGCAVRRLDVEAGRIRGVITEKGRVNATAVVVAGGAWSRLFLRNEGLFLPQLKVLNSVMR
LSPVKGVPETALWAAGFGLRKRMDGGYTVASGGENTFDIVPDTFRIGHRFIPAFLRDVTALRFRVSDRWRIESAEARPWS
GQDRSPFEETRVLDPQPSQKALRRGLAAVRDAFPALEKADVTQSWGGLIDVTPDEIPVISEVISRPGLFVSTGYSGHGFG
LGPGAGRLTADLVTGDAPIVDPRPFRLSRFGA

Specific function: Oxidative deamination of D-amino acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=434, Percent_Identity=25.5760368663594, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI21361378, Length=434, Percent_Identity=25.5760368663594, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI24797151, Length=432, Percent_Identity=22.9166666666667, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI194306651, Length=427, Percent_Identity=25.2927400468384, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994045, Length=240, Percent_Identity=25.4166666666667, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130091, Length=424, Percent_Identity=27.3584905660377, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571104, Length=431, Percent_Identity=23.6658932714617, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 47115; Mature: 46984

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPQLPHFNSDRVLPKAVDVVIIGGGIVGASTALELAERGHSVLLCEKGQIAGEQSSRN
CCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
WGWVRMSQRDPREMELMTHSQRIWEGLDMRTGYATGYTKCGIMFTAHTRKREAELSAWSE
CCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
HLKAIGGEGHMLRGESLEQLTPGYGHRIRAGFYTPQDGCAEPQMATHAIASAARDKGAVV
HHHHCCCCCCEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
ITGCAVRRLDVEAGRIRGVITEKGRVNATAVVVAGGAWSRLFLRNEGLFLPQLKVLNSVM
EEECEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHH
RLSPVKGVPETALWAAGFGLRKRMDGGYTVASGGENTFDIVPDTFRIGHRFIPAFLRDVT
HHCCCCCCCCHHHHHHCCCHHHHCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
ALRFRVSDRWRIESAEARPWSGQDRSPFEETRVLDPQPSQKALRRGLAAVRDAFPALEKA
HHEEEECCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DVTQSWGGLIDVTPDEIPVISEVISRPGLFVSTGYSGHGFGLGPGAGRLTADLVTGDAPI
CCHHHCCCEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC
VDPRPFRLSRFGA
CCCCCCCCCCCCC
>Mature Secondary Structure 
PGPQLPHFNSDRVLPKAVDVVIIGGGIVGASTALELAERGHSVLLCEKGQIAGEQSSRN
CCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
WGWVRMSQRDPREMELMTHSQRIWEGLDMRTGYATGYTKCGIMFTAHTRKREAELSAWSE
CCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHH
HLKAIGGEGHMLRGESLEQLTPGYGHRIRAGFYTPQDGCAEPQMATHAIASAARDKGAVV
HHHHCCCCCCEECCCCHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
ITGCAVRRLDVEAGRIRGVITEKGRVNATAVVVAGGAWSRLFLRNEGLFLPQLKVLNSVM
EEECEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHH
RLSPVKGVPETALWAAGFGLRKRMDGGYTVASGGENTFDIVPDTFRIGHRFIPAFLRDVT
HHCCCCCCCCHHHHHHCCCHHHHCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
ALRFRVSDRWRIESAEARPWSGQDRSPFEETRVLDPQPSQKALRRGLAAVRDAFPALEKA
HHEEEECCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DVTQSWGGLIDVTPDEIPVISEVISRPGLFVSTGYSGHGFGLGPGAGRLTADLVTGDAPI
CCHHHCCCEEECCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCC
VDPRPFRLSRFGA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10792736 [H]