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The map label for this gene is tesA [C]

Identifier: 99082109

GI number: 99082109

Start: 2383855

End: 2384532

Strand: Reverse

Name: tesA [C]

Synonym: TM1040_2269

Alternate gene names: 99082109

Gene position: 2384532-2383855 (Counterclockwise)

Preceding gene: 99082112

Following gene: 99082108

Centisome position: 74.49

GC content: 63.72

Gene sequence:

>678_bases
ATGCGCAAGTTTCTAAAGCAAATTGTGGTCAGTTTGGTGAGCATTCCATTGCTCCTGGGCGTGGCGCAGGCGGAGCCCGT
GCGGATCACCGCTTTTGGCGATAGCTTGGTGCAGGGCTATGGGCTGCCCCAGGGCGAGGGTCTGGTGGCGCAGCTGCGGG
ACTGGTTCGCGGTGGAGGGCTTTGATGTCGCGCTGACCAATGCGGGGGTCTCTGGCGACACCACCGCCGGCGGCGCGGCG
CGCATCGATTGGACCCTTGCGGAAACCCCGGACGCCATGATCGTGCTCCTGGGCGGAAATGACCTGCTGCGCGGACTTCC
CCCCGAAGACACCCGCGCCAATCTCAGCCGGATCATTGAGGCCGCGCGCGGGGCAGGGGCCGAAGTGCTGCTCATCGGGA
TGCAGGCGCCGGGCAATTATGGCGCCGACTACAAGGCCGCTTTTGACAGTATCTATCCGGATCTGACCGCGACGCATGAT
CTTGTGCTGCACCCGTTTGCCTTTGCCGGGATGGCCGCAGAAGCAGGAGAGGATCCGGCCCAGATGGGCGCCTACATGCA
GGCGGATGGCATCCATCCCAATGCGCGTGGTGTCGCCTTGAATATCAAGGCGATGGAGCCCGCCCTTCACGCGCTGATGG
CGCGGCTTTCACAACCTGAGGACAGCGCCAACAACTAG

Upstream 100 bases:

>100_bases
CAAATGCACATCTTGAAGCGTAAGAATGGGGCGGGCATCGGTGCTCATCTGTGGGTCCCTATCTCTTTTGATCTCGTTTG
GATATGGAGTGTCCCGAGCC

Downstream 100 bases:

>100_bases
GACGTGCCGTCAAAACAGCACAATCCGCCTTGCTGCGGTGATGTGGCGCTTGACCTCGCGCATGGGATTGCCCATGGCAC
CCTAAAGCGGCCTGCAGGCC

Product: lipolytic enzyme, G-D-S-L

Products: NA

Alternate protein names: Aryl-ester hydrolase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRKFLKQIVVSLVSIPLLLGVAQAEPVRITAFGDSLVQGYGLPQGEGLVAQLRDWFAVEGFDVALTNAGVSGDTTAGGAA
RIDWTLAETPDAMIVLLGGNDLLRGLPPEDTRANLSRIIEAARGAGAEVLLIGMQAPGNYGADYKAAFDSIYPDLTATHD
LVLHPFAFAGMAAEAGEDPAQMGAYMQADGIHPNARGVALNIKAMEPALHALMARLSQPEDSANN

Sequences:

>Translated_225_residues
MRKFLKQIVVSLVSIPLLLGVAQAEPVRITAFGDSLVQGYGLPQGEGLVAQLRDWFAVEGFDVALTNAGVSGDTTAGGAA
RIDWTLAETPDAMIVLLGGNDLLRGLPPEDTRANLSRIIEAARGAGAEVLLIGMQAPGNYGADYKAAFDSIYPDLTATHD
LVLHPFAFAGMAAEAGEDPAQMGAYMQADGIHPNARGVALNIKAMEPALHALMARLSQPEDSANN
>Mature_225_residues
MRKFLKQIVVSLVSIPLLLGVAQAEPVRITAFGDSLVQGYGLPQGEGLVAQLRDWFAVEGFDVALTNAGVSGDTTAGGAA
RIDWTLAETPDAMIVLLGGNDLLRGLPPEDTRANLSRIIEAARGAGAEVLLIGMQAPGNYGADYKAAFDSIYPDLTATHD
LVLHPFAFAGMAAEAGEDPAQMGAYMQADGIHPNARGVALNIKAMEPALHALMARLSQPEDSANN

Specific function: Favors the hydrolysis of several arylesters [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=189, Percent_Identity=35.978835978836, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 23565; Mature: 23565

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFLKQIVVSLVSIPLLLGVAQAEPVRITAFGDSLVQGYGLPQGEGLVAQLRDWFAVEG
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHEECC
FDVALTNAGVSGDTTAGGAARIDWTLAETPDAMIVLLGGNDLLRGLPPEDTRANLSRIIE
CEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHH
AARGAGAEVLLIGMQAPGNYGADYKAAFDSIYPDLTATHDLVLHPFAFAGMAAEAGEDPA
HHCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
QMGAYMQADGIHPNARGVALNIKAMEPALHALMARLSQPEDSANN
HHCCEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRKFLKQIVVSLVSIPLLLGVAQAEPVRITAFGDSLVQGYGLPQGEGLVAQLRDWFAVEG
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCHHHHHHHHHEECC
FDVALTNAGVSGDTTAGGAARIDWTLAETPDAMIVLLGGNDLLRGLPPEDTRANLSRIIE
CEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHH
AARGAGAEVLLIGMQAPGNYGADYKAAFDSIYPDLTATHDLVLHPFAFAGMAAEAGEDPA
HHCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
QMGAYMQADGIHPNARGVALNIKAMEPALHALMARLSQPEDSANN
HHCCEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141782 [H]