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The map label for this gene is yhcS [C]

Identifier: 99082087

GI number: 99082087

Start: 2361048

End: 2361980

Strand: Direct

Name: yhcS [C]

Synonym: TM1040_2247

Alternate gene names: 99082087

Gene position: 2361048-2361980 (Clockwise)

Preceding gene: 99082070

Following gene: 99082091

Centisome position: 73.76

GC content: 64.42

Gene sequence:

>933_bases
ATGGACCGCATTCAAAGCATGCAGGTGTTTGTCGCCGTCGCCGAAGAAGAGGGCTTTGCCGCGGGCGCGCGCCGGATGGG
GCTGAGCGCGCCATCGGCCACGCGGGCGATCAACGGGCTTGAGACACAGCTAGGCGCGCGACTCTTTACACGTACCACCC
GGCGGCTGCATCTGACGGACGTGGGGCAGCGCTACCTTGAGGACGTGCGCCATATCCTGACCTCATTGCAGGCGGCAGAC
GATACAGCGCGCGGCGCGGCCAGCGCGCCGGTGGGTCTGTTACGTCTCACCTGCCCCAATGAATTCGGTCGCATCTACAT
CCTGCCGATCCTGCTGGATTATCTCGATCATTATCCCGACATGCGCGCAGAATTGGTCCTGTTGGACCGGGTGGTGAACA
TCGTCGAAGAAGGCTTCGACGTGGCCCTGCGCATCGGCCATCTGCCCTCCTCGACGCTCTCGGCGGTAAAGGTCGGAGCG
GTGCGCCGGGTGCTCTGCGCGGCTCCCGCTTATCTGGAGCGGTACGGCACACCAGAAACTCCGGCGGATCTGAGCGCGCA
TCGCATCGTGGCTGTCAATGTGATCTCTTCTGCGACCGAATGGCGGTTCGGCGCCCAACAAGAGATCGCCGTGCGCATCG
CGCCGCAACTCTGTGTGAGCACCGTTGCAGCCGGGCGTGACGCGGCGCGCGAAGGCTGGGGGCTGTGCCGGATGCTCTCG
TATCAGGCCGGACGCGATGTCGCGGAGGGGCACCTGACCTGCCTGCTCGAAGACTATGAGCCAGAAAGCATGCCGATTCA
TCTGGTTCACACCGAAGGACGGCGCGCCCCAGCCAAGGTGCGCAGCTTTATCGATTTTGCCCGCGACCGGCTGCGCGCGG
ACCCGGTGCTTCAGGCCTTGTCATCCAGCAAGGGCTGTGGGCTGAGCGCTTAG

Upstream 100 bases:

>100_bases
TTCGCCTCTGTCGAGAGAGATAAATCAACCCGTTGTGTAAAATAATACGGCGTGTCAGAAAGAGATAATTTCACGTTTTG
ATAGCAATCGGAGCCAATGC

Downstream 100 bases:

>100_bases
AAATCAAGCCCCAGATCGACGGTGCGCGCCGAATGCGTGAGCGCCCCCGAGGAGATGAAATCCACCCCCGTGGCTGCAAT
TTCCGCCACTGTGTCGCGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDRIQSMQVFVAVAEEEGFAAGARRMGLSAPSATRAINGLETQLGARLFTRTTRRLHLTDVGQRYLEDVRHILTSLQAAD
DTARGAASAPVGLLRLTCPNEFGRIYILPILLDYLDHYPDMRAELVLLDRVVNIVEEGFDVALRIGHLPSSTLSAVKVGA
VRRVLCAAPAYLERYGTPETPADLSAHRIVAVNVISSATEWRFGAQQEIAVRIAPQLCVSTVAAGRDAAREGWGLCRMLS
YQAGRDVAEGHLTCLLEDYEPESMPIHLVHTEGRRAPAKVRSFIDFARDRLRADPVLQALSSSKGCGLSA

Sequences:

>Translated_310_residues
MDRIQSMQVFVAVAEEEGFAAGARRMGLSAPSATRAINGLETQLGARLFTRTTRRLHLTDVGQRYLEDVRHILTSLQAAD
DTARGAASAPVGLLRLTCPNEFGRIYILPILLDYLDHYPDMRAELVLLDRVVNIVEEGFDVALRIGHLPSSTLSAVKVGA
VRRVLCAAPAYLERYGTPETPADLSAHRIVAVNVISSATEWRFGAQQEIAVRIAPQLCVSTVAAGRDAAREGWGLCRMLS
YQAGRDVAEGHLTCLLEDYEPESMPIHLVHTEGRRAPAKVRSFIDFARDRLRADPVLQALSSSKGCGLSA
>Mature_310_residues
MDRIQSMQVFVAVAEEEGFAAGARRMGLSAPSATRAINGLETQLGARLFTRTTRRLHLTDVGQRYLEDVRHILTSLQAAD
DTARGAASAPVGLLRLTCPNEFGRIYILPILLDYLDHYPDMRAELVLLDRVVNIVEEGFDVALRIGHLPSSTLSAVKVGA
VRRVLCAAPAYLERYGTPETPADLSAHRIVAVNVISSATEWRFGAQQEIAVRIAPQLCVSTVAAGRDAAREGWGLCRMLS
YQAGRDVAEGHLTCLLEDYEPESMPIHLVHTEGRRAPAKVRSFIDFARDRLRADPVLQALSSSKGCGLSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=30.1003344481605, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=29.7029702970297, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=30.6049822064057, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=31.4878892733564, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=27.8169014084507, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=26.7361111111111, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=29.4520547945205, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789173, Length=284, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788706, Length=210, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=161, Percent_Identity=34.1614906832298, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33844; Mature: 33844

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIQSMQVFVAVAEEEGFAAGARRMGLSAPSATRAINGLETQLGARLFTRTTRRLHLTD
CCCHHHEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHH
VGQRYLEDVRHILTSLQAADDTARGAASAPVGLLRLTCPNEFGRIYILPILLDYLDHYPD
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCC
MRAELVLLDRVVNIVEEGFDVALRIGHLPSSTLSAVKVGAVRRVLCAAPAYLERYGTPET
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
PADLSAHRIVAVNVISSATEWRFGAQQEIAVRIAPQLCVSTVAAGRDAAREGWGLCRMLS
CCCCCCCEEEEEEEHHHHHHHCCCCCHHHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YQAGRDVAEGHLTCLLEDYEPESMPIHLVHTEGRRAPAKVRSFIDFARDRLRADPVLQAL
HHCCCCHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
SSSKGCGLSA
HCCCCCCCCC
>Mature Secondary Structure
MDRIQSMQVFVAVAEEEGFAAGARRMGLSAPSATRAINGLETQLGARLFTRTTRRLHLTD
CCCHHHEEEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHH
VGQRYLEDVRHILTSLQAADDTARGAASAPVGLLRLTCPNEFGRIYILPILLDYLDHYPD
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHCCCC
MRAELVLLDRVVNIVEEGFDVALRIGHLPSSTLSAVKVGAVRRVLCAAPAYLERYGTPET
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
PADLSAHRIVAVNVISSATEWRFGAQQEIAVRIAPQLCVSTVAAGRDAAREGWGLCRMLS
CCCCCCCEEEEEEEHHHHHHHCCCCCHHHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YQAGRDVAEGHLTCLLEDYEPESMPIHLVHTEGRRAPAKVRSFIDFARDRLRADPVLQAL
HHCCCCHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
SSSKGCGLSA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]