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The map label for this gene is yciR [C]

Identifier: 99082069

GI number: 99082069

Start: 2342347

End: 2344095

Strand: Reverse

Name: yciR [C]

Synonym: TM1040_2229

Alternate gene names: 99082069

Gene position: 2344095-2342347 (Counterclockwise)

Preceding gene: 99082071

Following gene: 99082066

Centisome position: 73.23

GC content: 58.26

Gene sequence:

>1749_bases
ATGGAGCAGGCGCGTCAGTTGAACCGGATGTCGCAGCGCGTGACGGCCGCGATGGAGGCCTCCAAAGATGGCTTTGCGAT
CTTCGACGAAGAAAACCGTCTCGTGACCTGCAACGATCGTTATCGAGAATTGAGCCATGTTCACCCCGACAAAGTTGTGC
CCGGCATGACCCTCACGGAGATCCTCGCTGACGCGGTAGAATCCGGGCACTATTTGCTGCGTGGGGTTTCGGCCAAGGAT
TACATCCAGAATTACAACCAACGCATCGTCAACCATGGCTTTTGTACAGAAACCCAGCTGGAACTGGCTGGCGATCGCCA
TATCGTGTCACGGGTGAATGAAACCGATTTTGGCGACAAGGTGGTGACACGCATCTGCATTACAGATCTGGTGCGGAATG
AACGGGAACAGCGCCGCGCCGCGCAGGCGCTCAGAGAGACGAAAGACCGGTTGGAGTTGCAATCCCTCAGCGATCCACTG
ACGCATTTGCCCAACCGGCGACACCTGGATCGCGAGCTGAGCCGAAGATTGCAGACAGAACCCGTTGCTCTGGTGCGGAT
CGACCTGGACCGGTTCAAGAAAATCAACGACATCCTCGGCCACGAGGCCGGGGACTATGTGCTTTGCCACGTGGCGGATG
TGCTTCGGGCGCACACGAAGGCGGGGGATGTTCCCGCGCGGGTGGGAGGCGACGAATTTGTCGTTCTCTGTCGATCCGGG
ACAACGCTCGAGCAGGCGCAAACCCTGGCGACTCGGGTGCTTCGGGCGGTGCTAGAGCCTGTGGTCTGGGGCAACAAGCG
CTGCAATTTCGGGGCAAGCTTTGGGGTCGCGCATGGCGTTCCCGGTGAAATCACGGCCAGCGAGTTGCTGAGCAATGCGG
ATGCGGCGCTCTACCGGGCGAAGGCTTCGGGGCGCGGCGCGGTAGAAGTTTTCACATCCGAGATGCGGGCAGAGGTACTG
GAAGAGCGCGCGCTCTCGGACCGACTGCCCTATGCGATCGAGGCAGGCGAAATAACGCCCTATTATCACACGCAGCATGA
TGCTCTGACCTGGCATCTAGCCGGGGTTGAGGTGCTGGCGCGCTGGGAGCATCCCGACCGCGGTGTACTGCCCCCCGACA
GGTTTCTGGGCATTGCCAAGCAGCTTGGGCTTGAGGCGGAGTTGGATGGCTGCATCTTTGACAGGGCGGTGGCGGATATG
CGCAGCCTGCGCGCCGAGGGCATTCTGGTGCGGCGGGTGGCATTCAACGTAAGCGCGGCGCGCATCATGCAGCCGAGCTT
TATCGAAACGGTCCGCGCACGCATCCCCGATCAGCGCGAGAGTTACGCGTTTGAAATTCTGGAATCGATCTCCTGCGAGG
ATGAGGGCGAGGCGCTGATCTTCTGCATCGATGCGCTGAAGGATCTTGGTTTTCAGATTGATGTCGACGATTTCGGATCC
GGCCATGCGTCGATCAATGGCGTCCTCAACATCGAGCCGGACGCCCTGAAAATCGACAGAAATATCATCTTCCCGCTTGG
AAAAAGCGAGCGCGCGGAACGAATGGTGGCGTCAGTTGTGGACCTTGCACACACTTTGGATGTGAAGATCATCGCCGAGG
GGGTGGATACCATTGAAAAAGCAAAAACACTCGGCGCCATCGGTTGCGATATATTACAGGGGTTTTATTTCTCCAAACCA
CGTAGCTTTGCAGAATTGAAAAAGAACCTCGAAAGGTTGGATCTCGGCGATCAGGTGTCCAACCTGTGA

Upstream 100 bases:

>100_bases
GGTCCGAATTGTCAAAACCGGCACCGCTGTGATCAGCCTCTGTCTGGTGTTGTTCTTTGTGTTTCTCGCCCGTCAGATGG
CGCGCGCGTGGCATCTCCAT

Downstream 100 bases:

>100_bases
GGTTTTCTCTCTAAGCGCTTTCACAGGCTTTGGAATTGTTTTTGGTATGCATGCCTATTTGTCCTGCTCGGGTAAAGTCA
CCAAGCACAAACCATCCATG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MEQARQLNRMSQRVTAAMEASKDGFAIFDEENRLVTCNDRYRELSHVHPDKVVPGMTLTEILADAVESGHYLLRGVSAKD
YIQNYNQRIVNHGFCTETQLELAGDRHIVSRVNETDFGDKVVTRICITDLVRNEREQRRAAQALRETKDRLELQSLSDPL
THLPNRRHLDRELSRRLQTEPVALVRIDLDRFKKINDILGHEAGDYVLCHVADVLRAHTKAGDVPARVGGDEFVVLCRSG
TTLEQAQTLATRVLRAVLEPVVWGNKRCNFGASFGVAHGVPGEITASELLSNADAALYRAKASGRGAVEVFTSEMRAEVL
EERALSDRLPYAIEAGEITPYYHTQHDALTWHLAGVEVLARWEHPDRGVLPPDRFLGIAKQLGLEAELDGCIFDRAVADM
RSLRAEGILVRRVAFNVSAARIMQPSFIETVRARIPDQRESYAFEILESISCEDEGEALIFCIDALKDLGFQIDVDDFGS
GHASINGVLNIEPDALKIDRNIIFPLGKSERAERMVASVVDLAHTLDVKIIAEGVDTIEKAKTLGAIGCDILQGFYFSKP
RSFAELKKNLERLDLGDQVSNL

Sequences:

>Translated_582_residues
MEQARQLNRMSQRVTAAMEASKDGFAIFDEENRLVTCNDRYRELSHVHPDKVVPGMTLTEILADAVESGHYLLRGVSAKD
YIQNYNQRIVNHGFCTETQLELAGDRHIVSRVNETDFGDKVVTRICITDLVRNEREQRRAAQALRETKDRLELQSLSDPL
THLPNRRHLDRELSRRLQTEPVALVRIDLDRFKKINDILGHEAGDYVLCHVADVLRAHTKAGDVPARVGGDEFVVLCRSG
TTLEQAQTLATRVLRAVLEPVVWGNKRCNFGASFGVAHGVPGEITASELLSNADAALYRAKASGRGAVEVFTSEMRAEVL
EERALSDRLPYAIEAGEITPYYHTQHDALTWHLAGVEVLARWEHPDRGVLPPDRFLGIAKQLGLEAELDGCIFDRAVADM
RSLRAEGILVRRVAFNVSAARIMQPSFIETVRARIPDQRESYAFEILESISCEDEGEALIFCIDALKDLGFQIDVDDFGS
GHASINGVLNIEPDALKIDRNIIFPLGKSERAERMVASVVDLAHTLDVKIIAEGVDTIEKAKTLGAIGCDILQGFYFSKP
RSFAELKKNLERLDLGDQVSNL
>Mature_582_residues
MEQARQLNRMSQRVTAAMEASKDGFAIFDEENRLVTCNDRYRELSHVHPDKVVPGMTLTEILADAVESGHYLLRGVSAKD
YIQNYNQRIVNHGFCTETQLELAGDRHIVSRVNETDFGDKVVTRICITDLVRNEREQRRAAQALRETKDRLELQSLSDPL
THLPNRRHLDRELSRRLQTEPVALVRIDLDRFKKINDILGHEAGDYVLCHVADVLRAHTKAGDVPARVGGDEFVVLCRSG
TTLEQAQTLATRVLRAVLEPVVWGNKRCNFGASFGVAHGVPGEITASELLSNADAALYRAKASGRGAVEVFTSEMRAEVL
EERALSDRLPYAIEAGEITPYYHTQHDALTWHLAGVEVLARWEHPDRGVLPPDRFLGIAKQLGLEAELDGCIFDRAVADM
RSLRAEGILVRRVAFNVSAARIMQPSFIETVRARIPDQRESYAFEILESISCEDEGEALIFCIDALKDLGFQIDVDDFGS
GHASINGVLNIEPDALKIDRNIIFPLGKSERAERMVASVVDLAHTLDVKIIAEGVDTIEKAKTLGAIGCDILQGFYFSKP
RSFAELKKNLERLDLGDQVSNL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=30.6603773584906, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=26.8348623853211, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=29.5833333333333, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI226510982, Length=416, Percent_Identity=26.2019230769231, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787055, Length=359, Percent_Identity=26.7409470752089, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788381, Length=191, Percent_Identity=38.7434554973822, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788502, Length=237, Percent_Identity=27.4261603375527, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788849, Length=447, Percent_Identity=24.6085011185682, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=27.734375, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786507, Length=234, Percent_Identity=27.7777777777778, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081881, Length=209, Percent_Identity=35.4066985645933, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082007, Length=221, Percent_Identity=33.4841628959276, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=36.1581920903955, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081980, Length=225, Percent_Identity=28.4444444444444, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=27.5423728813559, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787262, Length=176, Percent_Identity=35.2272727272727, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081977, Length=166, Percent_Identity=33.7349397590361, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=33.1325301204819, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082096, Length=214, Percent_Identity=25.7009345794392, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=32.5, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=32.5966850828729, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=99, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=35.031847133758, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 64911; Mature: 64911

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQARQLNRMSQRVTAAMEASKDGFAIFDEENRLVTCNDRYRELSHVHPDKVVPGMTLTE
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECHHHHHHHCCCCCCCCCCCHHHH
ILADAVESGHYLLRGVSAKDYIQNYNQRIVNHGFCTETQLELAGDRHIVSRVNETDFGDK
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCCCHHH
VVTRICITDLVRNEREQRRAAQALRETKDRLELQSLSDPLTHLPNRRHLDRELSRRLQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCC
PVALVRIDLDRFKKINDILGHEAGDYVLCHVADVLRAHTKAGDVPARVGGDEFVVLCRSG
CEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
TTLEQAQTLATRVLRAVLEPVVWGNKRCNFGASFGVAHGVPGEITASELLSNADAALYRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
KASGRGAVEVFTSEMRAEVLEERALSDRLPYAIEAGEITPYYHTQHDALTWHLAGVEVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECCCCCEEEEEHHHHHHH
RWEHPDRGVLPPDRFLGIAKQLGLEAELDGCIFDRAVADMRSLRAEGILVRRVAFNVSAA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCHHH
RIMQPSFIETVRARIPDQRESYAFEILESISCEDEGEALIFCIDALKDLGFQIDVDDFGS
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCEEEECCCCC
GHASINGVLNIEPDALKIDRNIIFPLGKSERAERMVASVVDLAHTLDVKIIAEGVDTIEK
CCCEECEEEEECCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTLGAIGCDILQGFYFSKPRSFAELKKNLERLDLGDQVSNL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MEQARQLNRMSQRVTAAMEASKDGFAIFDEENRLVTCNDRYRELSHVHPDKVVPGMTLTE
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECHHHHHHHCCCCCCCCCCCHHHH
ILADAVESGHYLLRGVSAKDYIQNYNQRIVNHGFCTETQLELAGDRHIVSRVNETDFGDK
HHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCCCHHH
VVTRICITDLVRNEREQRRAAQALRETKDRLELQSLSDPLTHLPNRRHLDRELSRRLQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCC
PVALVRIDLDRFKKINDILGHEAGDYVLCHVADVLRAHTKAGDVPARVGGDEFVVLCRSG
CEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
TTLEQAQTLATRVLRAVLEPVVWGNKRCNFGASFGVAHGVPGEITASELLSNADAALYRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
KASGRGAVEVFTSEMRAEVLEERALSDRLPYAIEAGEITPYYHTQHDALTWHLAGVEVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECCCCCEEEEEHHHHHHH
RWEHPDRGVLPPDRFLGIAKQLGLEAELDGCIFDRAVADMRSLRAEGILVRRVAFNVSAA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHCCHHH
RIMQPSFIETVRARIPDQRESYAFEILESISCEDEGEALIFCIDALKDLGFQIDVDDFGS
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCEEEECCCCC
GHASINGVLNIEPDALKIDRNIIFPLGKSERAERMVASVVDLAHTLDVKIIAEGVDTIEK
CCCEECEEEEECCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTLGAIGCDILQGFYFSKPRSFAELKKNLERLDLGDQVSNL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]