Click here to switch to the map view.

The map label for this gene is mhpR [H]

Identifier: 99081952

GI number: 99081952

Start: 2217033

End: 2217839

Strand: Reverse

Name: mhpR [H]

Synonym: TM1040_2112

Alternate gene names: 99081952

Gene position: 2217839-2217033 (Counterclockwise)

Preceding gene: 99081958

Following gene: 99081950

Centisome position: 69.29

GC content: 61.09

Gene sequence:

>807_bases
ATGCTGAAAGAAAATCGCTCTCTGGATCGTGGTATCGAAATTCTGGAAACCCTCGCGCGCGAGGGAGCGATGTCGCTTGC
GGATCTGCACCGGGCGACAGGCCTGCCCAAGAGCACGCTGCGCCGTCTTTTGCAGACCTTGATTGCGCGCAAGATTGTGC
GCCGTTCCCTTGCAGACAAGCTCTATCGGACCTTGGTTGTATTTCCAGATATTTCGGGCGAGGTCATGCCAAAGGGGATG
CTGCATATCTCAGAGGCGGCGATCCCGCGGGCGCTTGCGTTGACCAAGGAGATTGGCTGGCCGTCCGACATCCATATCCG
CGAAACGCGTGCGATGCGGATCATCGACAATACCCGCCACGCCAGCACCTTTCACGTCGAGCGCGGCCAGATCAACCAGC
GTGTCAGCCATTTTGGCTCGGCCACTGGGCTCGCCTGTCTGGCAGAGATGAAAGATGCTGAAATCGCTACCATCTACGAG
GCCTTCAAGCCCGATCTTCAGTGGGGTCCGGTGCGTTTTGGGCTGGACCTCGCGGGGCTGATGGCGCGGATCGAACAGGT
GCGCCAAGTGGGCTATGCGGAGCGCCTCTCTGCGCCGATGAGCGATCCGGATTGGGACACCGATTTGCGCGCCATCGCCG
TCGCCATCAAGGCCCGTGGGCGCGTGGTGGGCGGTCTGTCGGTGCTCTGGCTCAGGCCCTACAAACCTGTCGAAGAATTC
GCTCGCCTGCATCTTGAGGCACTGCAAACCGCGGCCGCCGAGATCAACGCCACGCTTGATGCCGTGTGGGAGGACGCTGC
GACCTGA

Upstream 100 bases:

>100_bases
ATAGCGCATGCCTTGTTCCGAGTGCCAAAACGACGATAGGTTAGGTCGGGAGGCACAAAAACCCTTTGGCAAAACATGCC
GCTGGGTGGCATGACGAGAT

Downstream 100 bases:

>100_bases
TGCGCCCCGGAGTTTCAGGTCAGCGCGCGTCTTACGTGCGCCCCGCCTGGTGTCAGAGAATGCTCTCTGCCGCCTGTTTG
GCGAGAAACGCGCTCCGATA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLKENRSLDRGIEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLADKLYRTLVVFPDISGEVMPKGM
LHISEAAIPRALALTKEIGWPSDIHIRETRAMRIIDNTRHASTFHVERGQINQRVSHFGSATGLACLAEMKDAEIATIYE
AFKPDLQWGPVRFGLDLAGLMARIEQVRQVGYAERLSAPMSDPDWDTDLRAIAVAIKARGRVVGGLSVLWLRPYKPVEEF
ARLHLEALQTAAAEINATLDAVWEDAAT

Sequences:

>Translated_268_residues
MLKENRSLDRGIEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLADKLYRTLVVFPDISGEVMPKGM
LHISEAAIPRALALTKEIGWPSDIHIRETRAMRIIDNTRHASTFHVERGQINQRVSHFGSATGLACLAEMKDAEIATIYE
AFKPDLQWGPVRFGLDLAGLMARIEQVRQVGYAERLSAPMSDPDWDTDLRAIAVAIKARGRVVGGLSVLWLRPYKPVEEF
ARLHLEALQTAAAEINATLDAVWEDAAT
>Mature_268_residues
MLKENRSLDRGIEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLADKLYRTLVVFPDISGEVMPKGM
LHISEAAIPRALALTKEIGWPSDIHIRETRAMRIIDNTRHASTFHVERGQINQRVSHFGSATGLACLAEMKDAEIATIYE
AFKPDLQWGPVRFGLDLAGLMARIEQVRQVGYAERLSAPMSDPDWDTDLRAIAVAIKARGRVVGGLSVLWLRPYKPVEEF
ARLHLEALQTAAAEINATLDAVWEDAAT

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29849; Mature: 29849

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKENRSLDRGIEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLADK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYRTLVVFPDISGEVMPKGMLHISEAAIPRALALTKEIGWPSDIHIRETRAMRIIDNTRH
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCC
ASTFHVERGQINQRVSHFGSATGLACLAEMKDAEIATIYEAFKPDLQWGPVRFGLDLAGL
CCEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
MARIEQVRQVGYAERLSAPMSDPDWDTDLRAIAVAIKARGRVVGGLSVLWLRPYKPVEEF
HHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECEEEEEECCCCCHHHH
ARLHLEALQTAAAEINATLDAVWEDAAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKENRSLDRGIEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLADK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYRTLVVFPDISGEVMPKGMLHISEAAIPRALALTKEIGWPSDIHIRETRAMRIIDNTRH
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCC
ASTFHVERGQINQRVSHFGSATGLACLAEMKDAEIATIYEAFKPDLQWGPVRFGLDLAGL
CCEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHH
MARIEQVRQVGYAERLSAPMSDPDWDTDLRAIAVAIKARGRVVGGLSVLWLRPYKPVEEF
HHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECEEEEEECCCCCHHHH
ARLHLEALQTAAAEINATLDAVWEDAAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]