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The map label for this gene is pyc [H]

Identifier: 99081868

GI number: 99081868

Start: 2134246

End: 2137686

Strand: Direct

Name: pyc [H]

Synonym: TM1040_2028

Alternate gene names: 99081868

Gene position: 2134246-2137686 (Clockwise)

Preceding gene: 99081866

Following gene: 99081869

Centisome position: 66.68

GC content: 62.28

Gene sequence:

>3441_bases
ATGACTGAGTTCAACAAAATCTTGATCGCCAACCGTGGTGAGATCGCCATCCGCGTGATGCGCGCCGCCAACGAGATGGG
CAAACGCACCGTTGCTGTCTACGCGGAGGAGGACAAACTGGGCCTGCACCGCTTCAAGGCGGACGAAGCCTATCGTATTG
GCGAGGGTCTTGGCCCGGTCGCCGCTTATCTCTCGATTGACGAGATCATCCGCGTGGCCAAGGAATGCGGCGCGGATGCG
ATCCATCCGGGCTATGGCCTTTTGTCGGAGAACCCCGACTTTGTGGATGCCTGCGCCCGCAACGGTATCACCTTTATCGG
CCCCAAGGCCGAGACCATGCGCGCCCTTGGCGACAAGGCCAGCGCGCGCCGCGTCGCCATTGAGGCGGGCGTGCCAGTGA
TCCCCGCCACCGAGGTGCTGGGCGATGACATGGACGCGATCCGCAAAGAAGCGGCAGAGGTCGGCTATCCCCTGATGCTC
AAGGCGAGCTGGGGCGGCGGCGGACGCGGGATGCGCCCGATCCACTCCGAGGACGAGCTCGAGGAAAAGGTTCTGGAAGG
TCGCCGCGAGGCCGAAGCCGCATTCGGCAATGGCGAAGGCTATCTTGAGAAGATGATCACCCGCGCCCGTCACGTCGAGG
TGCAGATCCTTGGCGACAAGCACGGCGAGATCTATCACCTCTATGAGCGCGACTGTTCGGTGCAGCGCCGCAACCAGAAG
GTCGTGGAACGCGCGCCCGCGCCCTATCTCACGGATGCGCAACGCGCCGAGATCTGCGATCTGGGCCGCAAGATCTGCCA
GCATGTGAACTATGAATGTGCGGGCACCGTCGAATTCCTAATGGATATGGAGACGGAGAAGTTCTACTTCATCGAGGTGA
ACCCGCGGGTGCAGGTGGAACACACCGTCACCGAAGAAGTCACCGGCATCGACATCGTGCAGGCGCAGATCCTGATTGCC
GAGGGCAAGACCCTCGCAGAGGCCACCGGCAAGGCCAGCCAGGAAGAGATTTCGCTCAACGGGCATGCGCTGCAGACCCG
TGTGACCACCGAAGATCCTCTCAACAACTTCATCCCGGACTATGGCCGCATTACCGCCTATCGCTCGGCCACCGGCATGG
GCATCCGTCTGGATGGCGGCACCGCCTATGCGGGTGGGGTGATCACGCGCTACTATGACAGCCTGCTGACCAAGGTAACG
GCCAAAGCGCCAACGCCGGAGAAGGCCATCGCCCGTATGGACCGCGCGCTGCGCGAGTTCCGGGTGCGCGGTGTCAGCAC
AAACATCGCCTTTGTCGAGAACCTGCTGAAGCACCCCACGTTCCTCAACAATGAATACACCACCAAATTCATCGACGAGA
CGCCGGAGCTGTTCCAATTCGCCAAGCGGCGCGACCGGGGCACCAAGGTGCTGACCTATATCGCGGATATTTCCGTTAAC
GGTCATCCCGAGACCGAAGGCCGCGCCGCGCCAGCTGCCGACCTCAAAGAGCCGCGCGCGCCGCGCGCCGATACGGGCAA
CCTGCCCTATGGCACGCGGAACCTGCTGGAGCAAAAGGGCGCAAAGGCGGTTGCCGACTGGATGAAAGCGCAGCGTCAGC
TGCTCTTGACCGACACCACCATGCGCGACGGGCACCAGTCGCTGCTCGCCACCCGCATGCGGTCCATCGACATGATCAAG
GTCGCGCCTGCCTATGCACAGAACCTCAGCCAGCTGTTCTCGGTCGAGTGCTGGGGCGGGGCGACGTTCGATGTGGCCTA
TCGCTTTTTGCAGGAATGCCCCTGGCAGCGTCTGCGCGACCTGCGCGAGGCGATGCCGAACCTGATGACGCAGATGTTGC
TGCGCGCCTCCAACGGGGTGGGGTACACCAACTATCCCGACAACGTGGTGCAGTTCTTCGTCAAGGAAGCGGCCAAGGGT
ATCGACGTCTTCCGCGTGTTTGACAGCCTCAACTGGGTCGAGAACATGCGCGTCGCCATGGACGCCGTGGTCGAGAGCGG
CAAGATCTGCGAAGGCACCATCTGCTACACCGGCGACATCCTTGACCCGGCCCGCGCCAAATATGACGTGAAATACTACG
TCGGCATGGCCAAGGAACTGGAAGCCGCAGGCGCGCATGTGCTGGGCCTCAAGGACATGGCGGGTCTGTTGAAACCAGCC
TCGGCCAAGCTCTTGATCAAGGCGCTGAAGGAAGAGGTCGGCCTGCCGATCCACTTCCACACCCATGACACCTCTGGCAT
CGCGGGCGCGACCATTCTGGCCGCGGCAGATGCGGGCGTTGATGCGGTCGATGCGGCGATGGACGCGTTTTCCGGCGGCA
CCTCGCAGCCCTGTCTGGGGTCGATCGTGGAGGCGCTCAAGAACACAGACCGCGACACCGGTCTGGACATTGGCAACATC
CGCGAGATCTCGGAATACTGGGAGCAGGTGCGCGCGCAATACGCCGCCTTTGAATCCGGGCTGCAAGCGCCCGCGTCTGA
GGTCTATCTCCATGAGATGCCCGGCGGTCAGTTCACCAACCTCAAGGCACAGGCCCGCAGCCTTGGACTTGAGGAGCGCT
GGCACGAGGTTGCGCAGACCTATGCGGATGTGAACCAGATGTTTGGCGACATCGTCAAAGTGACCCCCTCCTCCAAGGTG
GTGGGTGACATGGCGCTGATGATGGTCTCTCAGGGGCTTACCCGCGCGCAGGTCGAAGATCCCAAATCCGAAGTCTCCTT
CCCCGACTCGGTGGTGGACATGATGCGCGGCAACCTGGGCCAGCCTCCGGGCGGTTTCCCCGAAAGCATCGTCAAGAAGG
TGCTGAAAGGCGAAGCCCCCAATGTTGAGCGCCCCGGTGCGCATCTGGAGCCGGTCGACATCGAGAGCACCCGCGCCGAA
CTCTCCAAAGAGCTCGAAGGCTTCAAGGTCGATGACGAGGATCTCAACGGCTATCTAATGTATCCGAAGGTGTTCCTCGA
TTACATGGGCCGCCATCGCCAATACGGCCCGGTGCGCGCGCTGCCGACCAAGACGTTCTTTTACGGGATGGAACCCGGTG
ACGAGATCACCGCTGAGATCGACCCCGGCAAGACGCTGGAAATCCGCCTGCAAGCCATTGGCGAGACGGATGAAAAAGGC
GAAGTGAAGGTGTTTTTCGAGCTGAACGGCCAGCCGCGCGTCATCCGCGTGCCCAACCGTCTGGTGAAATCCTCCACCAC
CCAGCGCCCAAAGGCCGAAGTAGGGAACATCAACCACATCGGTGCGCCGATGCCGGGTGTTGTGGCCTCCATCGGGGTTC
AGGTGGGCCAGCAGGTGCACGAGGGCGATCTCTTGCTGACCATCGAGGCGATGAAGATGGAGACCGGCCTGCACGCCGAG
CGCGACGCGGTGGTCAAGGCCGTCCACGTCCAGCCCGGTGGTCAGATCGACGCCAAGGATCTGCTGGTCGAACTGGAATG
A

Upstream 100 bases:

>100_bases
AAGTGAGCGCAATCATGCCGCAGATACCCAGAACCACGGATGGTCTGCGTGTCATACAGCCGTTACCACTTGCCCAACCT
AGCAAGACCTCGGGGGAAAG

Downstream 100 bases:

>100_bases
CCCAGGCCCCATGCTAAAATTCAGCCGCAGCTCCCCATCGGGGCTGCGGCTTTTTCATTTGGGGAATTCACATGAGCGAA
GAGACGACCGGACAGCTCCC

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1146; Mature: 1145

Protein sequence:

>1146_residues
MTEFNKILIANRGEIAIRVMRAANEMGKRTVAVYAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKECGADA
IHPGYGLLSENPDFVDACARNGITFIGPKAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMDAIRKEAAEVGYPLML
KASWGGGGRGMRPIHSEDELEEKVLEGRREAEAAFGNGEGYLEKMITRARHVEVQILGDKHGEIYHLYERDCSVQRRNQK
VVERAPAPYLTDAQRAEICDLGRKICQHVNYECAGTVEFLMDMETEKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIA
EGKTLAEATGKASQEEISLNGHALQTRVTTEDPLNNFIPDYGRITAYRSATGMGIRLDGGTAYAGGVITRYYDSLLTKVT
AKAPTPEKAIARMDRALREFRVRGVSTNIAFVENLLKHPTFLNNEYTTKFIDETPELFQFAKRRDRGTKVLTYIADISVN
GHPETEGRAAPAADLKEPRAPRADTGNLPYGTRNLLEQKGAKAVADWMKAQRQLLLTDTTMRDGHQSLLATRMRSIDMIK
VAPAYAQNLSQLFSVECWGGATFDVAYRFLQECPWQRLRDLREAMPNLMTQMLLRASNGVGYTNYPDNVVQFFVKEAAKG
IDVFRVFDSLNWVENMRVAMDAVVESGKICEGTICYTGDILDPARAKYDVKYYVGMAKELEAAGAHVLGLKDMAGLLKPA
SAKLLIKALKEEVGLPIHFHTHDTSGIAGATILAAADAGVDAVDAAMDAFSGGTSQPCLGSIVEALKNTDRDTGLDIGNI
REISEYWEQVRAQYAAFESGLQAPASEVYLHEMPGGQFTNLKAQARSLGLEERWHEVAQTYADVNQMFGDIVKVTPSSKV
VGDMALMMVSQGLTRAQVEDPKSEVSFPDSVVDMMRGNLGQPPGGFPESIVKKVLKGEAPNVERPGAHLEPVDIESTRAE
LSKELEGFKVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRALPTKTFFYGMEPGDEITAEIDPGKTLEIRLQAIGETDEKG
EVKVFFELNGQPRVIRVPNRLVKSSTTQRPKAEVGNINHIGAPMPGVVASIGVQVGQQVHEGDLLLTIEAMKMETGLHAE
RDAVVKAVHVQPGGQIDAKDLLVELE

Sequences:

>Translated_1146_residues
MTEFNKILIANRGEIAIRVMRAANEMGKRTVAVYAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKECGADA
IHPGYGLLSENPDFVDACARNGITFIGPKAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMDAIRKEAAEVGYPLML
KASWGGGGRGMRPIHSEDELEEKVLEGRREAEAAFGNGEGYLEKMITRARHVEVQILGDKHGEIYHLYERDCSVQRRNQK
VVERAPAPYLTDAQRAEICDLGRKICQHVNYECAGTVEFLMDMETEKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIA
EGKTLAEATGKASQEEISLNGHALQTRVTTEDPLNNFIPDYGRITAYRSATGMGIRLDGGTAYAGGVITRYYDSLLTKVT
AKAPTPEKAIARMDRALREFRVRGVSTNIAFVENLLKHPTFLNNEYTTKFIDETPELFQFAKRRDRGTKVLTYIADISVN
GHPETEGRAAPAADLKEPRAPRADTGNLPYGTRNLLEQKGAKAVADWMKAQRQLLLTDTTMRDGHQSLLATRMRSIDMIK
VAPAYAQNLSQLFSVECWGGATFDVAYRFLQECPWQRLRDLREAMPNLMTQMLLRASNGVGYTNYPDNVVQFFVKEAAKG
IDVFRVFDSLNWVENMRVAMDAVVESGKICEGTICYTGDILDPARAKYDVKYYVGMAKELEAAGAHVLGLKDMAGLLKPA
SAKLLIKALKEEVGLPIHFHTHDTSGIAGATILAAADAGVDAVDAAMDAFSGGTSQPCLGSIVEALKNTDRDTGLDIGNI
REISEYWEQVRAQYAAFESGLQAPASEVYLHEMPGGQFTNLKAQARSLGLEERWHEVAQTYADVNQMFGDIVKVTPSSKV
VGDMALMMVSQGLTRAQVEDPKSEVSFPDSVVDMMRGNLGQPPGGFPESIVKKVLKGEAPNVERPGAHLEPVDIESTRAE
LSKELEGFKVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRALPTKTFFYGMEPGDEITAEIDPGKTLEIRLQAIGETDEKG
EVKVFFELNGQPRVIRVPNRLVKSSTTQRPKAEVGNINHIGAPMPGVVASIGVQVGQQVHEGDLLLTIEAMKMETGLHAE
RDAVVKAVHVQPGGQIDAKDLLVELE
>Mature_1145_residues
TEFNKILIANRGEIAIRVMRAANEMGKRTVAVYAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKECGADAI
HPGYGLLSENPDFVDACARNGITFIGPKAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMDAIRKEAAEVGYPLMLK
ASWGGGGRGMRPIHSEDELEEKVLEGRREAEAAFGNGEGYLEKMITRARHVEVQILGDKHGEIYHLYERDCSVQRRNQKV
VERAPAPYLTDAQRAEICDLGRKICQHVNYECAGTVEFLMDMETEKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIAE
GKTLAEATGKASQEEISLNGHALQTRVTTEDPLNNFIPDYGRITAYRSATGMGIRLDGGTAYAGGVITRYYDSLLTKVTA
KAPTPEKAIARMDRALREFRVRGVSTNIAFVENLLKHPTFLNNEYTTKFIDETPELFQFAKRRDRGTKVLTYIADISVNG
HPETEGRAAPAADLKEPRAPRADTGNLPYGTRNLLEQKGAKAVADWMKAQRQLLLTDTTMRDGHQSLLATRMRSIDMIKV
APAYAQNLSQLFSVECWGGATFDVAYRFLQECPWQRLRDLREAMPNLMTQMLLRASNGVGYTNYPDNVVQFFVKEAAKGI
DVFRVFDSLNWVENMRVAMDAVVESGKICEGTICYTGDILDPARAKYDVKYYVGMAKELEAAGAHVLGLKDMAGLLKPAS
AKLLIKALKEEVGLPIHFHTHDTSGIAGATILAAADAGVDAVDAAMDAFSGGTSQPCLGSIVEALKNTDRDTGLDIGNIR
EISEYWEQVRAQYAAFESGLQAPASEVYLHEMPGGQFTNLKAQARSLGLEERWHEVAQTYADVNQMFGDIVKVTPSSKVV
GDMALMMVSQGLTRAQVEDPKSEVSFPDSVVDMMRGNLGQPPGGFPESIVKKVLKGEAPNVERPGAHLEPVDIESTRAEL
SKELEGFKVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRALPTKTFFYGMEPGDEITAEIDPGKTLEIRLQAIGETDEKGE
VKVFFELNGQPRVIRVPNRLVKSSTTQRPKAEVGNINHIGAPMPGVVASIGVQVGQQVHEGDLLLTIEAMKMETGLHAER
DAVVKAVHVQPGGQIDAKDLLVELE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1146, Percent_Identity=49.738219895288, Blast_Score=1075, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1146, Percent_Identity=49.738219895288, Blast_Score=1075, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1146, Percent_Identity=49.738219895288, Blast_Score=1075, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=455, Percent_Identity=42.4175824175824, Blast_Score=365, Evalue=1e-100,
Organism=Homo sapiens, GI189095269, Length=463, Percent_Identity=40.1727861771058, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI65506442, Length=460, Percent_Identity=40.4347826086956, Blast_Score=327, Evalue=4e-89,
Organism=Homo sapiens, GI295821183, Length=460, Percent_Identity=40.4347826086956, Blast_Score=327, Evalue=5e-89,
Organism=Homo sapiens, GI38679960, Length=559, Percent_Identity=30.4114490161002, Blast_Score=226, Evalue=7e-59,
Organism=Homo sapiens, GI38679977, Length=559, Percent_Identity=30.4114490161002, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI38679967, Length=559, Percent_Identity=30.4114490161002, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI38679974, Length=559, Percent_Identity=30.4114490161002, Blast_Score=226, Evalue=9e-59,
Organism=Homo sapiens, GI38679971, Length=559, Percent_Identity=30.4114490161002, Blast_Score=226, Evalue=1e-58,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=31.7647058823529, Blast_Score=216, Evalue=9e-56,
Organism=Escherichia coli, GI1789654, Length=451, Percent_Identity=44.7893569844789, Blast_Score=350, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17562816, Length=1154, Percent_Identity=51.1265164644714, Blast_Score=1126, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=457, Percent_Identity=44.6389496717724, Blast_Score=358, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17567343, Length=461, Percent_Identity=41.2147505422993, Blast_Score=333, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI133931226, Length=498, Percent_Identity=30.1204819277108, Blast_Score=213, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI71997163, Length=441, Percent_Identity=29.4784580498866, Blast_Score=199, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71997168, Length=441, Percent_Identity=29.4784580498866, Blast_Score=199, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1166, Percent_Identity=46.8267581475129, Blast_Score=1041, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1166, Percent_Identity=47.0840480274443, Blast_Score=1023, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=449, Percent_Identity=39.6436525612472, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6323863, Length=439, Percent_Identity=32.1184510250569, Blast_Score=211, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6324343, Length=516, Percent_Identity=30.8139534883721, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24652212, Length=1151, Percent_Identity=48.8271068635969, Blast_Score=1069, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1151, Percent_Identity=48.8271068635969, Blast_Score=1069, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1151, Percent_Identity=48.8271068635969, Blast_Score=1069, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1151, Percent_Identity=48.8271068635969, Blast_Score=1069, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1151, Percent_Identity=48.8271068635969, Blast_Score=1069, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1167, Percent_Identity=48.3290488431877, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1167, Percent_Identity=48.3290488431877, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1167, Percent_Identity=48.3290488431877, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1167, Percent_Identity=48.3290488431877, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1167, Percent_Identity=48.3290488431877, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=453, Percent_Identity=40.3973509933775, Blast_Score=347, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24651759, Length=415, Percent_Identity=39.0361445783133, Blast_Score=306, Evalue=8e-83,
Organism=Drosophila melanogaster, GI161076409, Length=512, Percent_Identity=29.1015625, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24586458, Length=512, Percent_Identity=29.1015625, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI161076407, Length=512, Percent_Identity=29.1015625, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24586460, Length=512, Percent_Identity=29.1015625, Blast_Score=197, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126090; Mature: 125959

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFNKILIANRGEIAIRVMRAANEMGKRTVAVYAEEDKLGLHRFKADEAYRIGEGLGPV
CCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHCCCCHHHHCCCCCHH
AAYLSIDEIIRVAKECGADAIHPGYGLLSENPDFVDACARNGITFIGPKAETMRALGDKA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEECCCHHHHHHHCCCC
SARRVAIEAGVPVIPATEVLGDDMDAIRKEAAEVGYPLMLKASWGGGGRGMRPIHSEDEL
CCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHH
EEKVLEGRREAEAAFGNGEGYLEKMITRARHVEVQILGDKHGEIYHLYERDCSVQRRNQK
HHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVERAPAPYLTDAQRAEICDLGRKICQHVNYECAGTVEFLMDMETEKFYFIEVNPRVQVE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEE
HTVTEEVTGIDIVQAQILIAEGKTLAEATGKASQEEISLNGHALQTRVTTEDPLNNFIPD
EEHHHHHCCCEEEEEEEEEECCCHHHHHCCCCCCHHEECCCCEEEEEECCCCCHHHHCCC
YGRITAYRSATGMGIRLDGGTAYAGGVITRYYDSLLTKVTAKAPTPEKAIARMDRALREF
CCCEEEEECCCCCEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RVRGVSTNIAFVENLLKHPTFLNNEYTTKFIDETPELFQFAKRRDRGTKVLTYIADISVN
HHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEEC
GHPETEGRAAPAADLKEPRAPRADTGNLPYGTRNLLEQKGAKAVADWMKAQRQLLLTDTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHEEEECCC
MRDGHQSLLATRMRSIDMIKVAPAYAQNLSQLFSVECWGGATFDVAYRFLQECPWQRLRD
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCHHHHHH
LREAMPNLMTQMLLRASNGVGYTNYPDNVVQFFVKEAAKGIDVFRVFDSLNWVENMRVAM
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAVVESGKICEGTICYTGDILDPARAKYDVKYYVGMAKELEAAGAHVLGLKDMAGLLKPA
HHHHHCCCCCCCEEEEECCCCCCHHCCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHCCC
SAKLLIKALKEEVGLPIHFHTHDTSGIAGATILAAADAGVDAVDAAMDAFSGGTSQPCLG
HHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHH
SIVEALKNTDRDTGLDIGNIREISEYWEQVRAQYAAFESGLQAPASEVYLHEMPGGQFTN
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCC
LKAQARSLGLEERWHEVAQTYADVNQMFGDIVKVTPSSKVVGDMALMMVSQGLTRAQVED
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHCCC
PKSEVSFPDSVVDMMRGNLGQPPGGFPESIVKKVLKGEAPNVERPGAHLEPVDIESTRAE
CHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
LSKELEGFKVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRALPTKTFFYGMEPGDEITAEI
HHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEE
DPGKTLEIRLQAIGETDEKGEVKVFFELNGQPRVIRVPNRLVKSSTTQRPKAEVGNINHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEECCHHHHHCCCCCCCCHHCCCCCCC
GAPMPGVVASIGVQVGQQVHEGDLLLTIEAMKMETGLHAERDAVVKAVHVQPGGQIDAKD
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCHHEEEEEECCCCCCCHHH
LLVELE
CEEECC
>Mature Secondary Structure 
TEFNKILIANRGEIAIRVMRAANEMGKRTVAVYAEEDKLGLHRFKADEAYRIGEGLGPV
CCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHCCCCHHHHCCCCCHH
AAYLSIDEIIRVAKECGADAIHPGYGLLSENPDFVDACARNGITFIGPKAETMRALGDKA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEECCCHHHHHHHCCCC
SARRVAIEAGVPVIPATEVLGDDMDAIRKEAAEVGYPLMLKASWGGGGRGMRPIHSEDEL
CCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHH
EEKVLEGRREAEAAFGNGEGYLEKMITRARHVEVQILGDKHGEIYHLYERDCSVQRRNQK
HHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVERAPAPYLTDAQRAEICDLGRKICQHVNYECAGTVEFLMDMETEKFYFIEVNPRVQVE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEE
HTVTEEVTGIDIVQAQILIAEGKTLAEATGKASQEEISLNGHALQTRVTTEDPLNNFIPD
EEHHHHHCCCEEEEEEEEEECCCHHHHHCCCCCCHHEECCCCEEEEEECCCCCHHHHCCC
YGRITAYRSATGMGIRLDGGTAYAGGVITRYYDSLLTKVTAKAPTPEKAIARMDRALREF
CCCEEEEECCCCCEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RVRGVSTNIAFVENLLKHPTFLNNEYTTKFIDETPELFQFAKRRDRGTKVLTYIADISVN
HHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEEC
GHPETEGRAAPAADLKEPRAPRADTGNLPYGTRNLLEQKGAKAVADWMKAQRQLLLTDTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHEEEECCC
MRDGHQSLLATRMRSIDMIKVAPAYAQNLSQLFSVECWGGATFDVAYRFLQECPWQRLRD
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCHHHHHH
LREAMPNLMTQMLLRASNGVGYTNYPDNVVQFFVKEAAKGIDVFRVFDSLNWVENMRVAM
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAVVESGKICEGTICYTGDILDPARAKYDVKYYVGMAKELEAAGAHVLGLKDMAGLLKPA
HHHHHCCCCCCCEEEEECCCCCCHHCCEEEHHHHHHHHHHHHCCCEEEEHHHHHHHHCCC
SAKLLIKALKEEVGLPIHFHTHDTSGIAGATILAAADAGVDAVDAAMDAFSGGTSQPCLG
HHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHH
SIVEALKNTDRDTGLDIGNIREISEYWEQVRAQYAAFESGLQAPASEVYLHEMPGGQFTN
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCC
LKAQARSLGLEERWHEVAQTYADVNQMFGDIVKVTPSSKVVGDMALMMVSQGLTRAQVED
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHCCC
PKSEVSFPDSVVDMMRGNLGQPPGGFPESIVKKVLKGEAPNVERPGAHLEPVDIESTRAE
CHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
LSKELEGFKVDDEDLNGYLMYPKVFLDYMGRHRQYGPVRALPTKTFFYGMEPGDEITAEI
HHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCEEEEE
DPGKTLEIRLQAIGETDEKGEVKVFFELNGQPRVIRVPNRLVKSSTTQRPKAEVGNINHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEECCHHHHHCCCCCCCCHHCCCCCCC
GAPMPGVVASIGVQVGQQVHEGDLLLTIEAMKMETGLHAERDAVVKAVHVQPGGQIDAKD
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCHHEEEEEECCCCCCCHHH
LLVELE
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]