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The map label for this gene is lldD [H]

Identifier: 99081866

GI number: 99081866

Start: 2132061

End: 2133230

Strand: Direct

Name: lldD [H]

Synonym: TM1040_2026

Alternate gene names: 99081866

Gene position: 2132061-2133230 (Clockwise)

Preceding gene: 99081865

Following gene: 99081868

Centisome position: 66.61

GC content: 66.32

Gene sequence:

>1170_bases
ATGGCGGGCATGACTTTGGATCAACGCTACCCCGCATTGGATGATTTGCGCGCCAAGGCCCGCACGCGTCTGCCCCGATT
TGTCTGGGAATACCTCGACAGCGCCACCGGGCGCGAAGCCACGCAGGCGCGCAACCGGCTCTGCCTTGACCGGATCGGGC
TGATGCCCGCAATCCTTGGTGGCCCGCAGGAGGTGGACCTTGGCACCACCTTGTTTGGTACCCCGTTGCCGCGCCCCTTT
GGCATTGCGCCGGTGGGGATGTCGGGGCTGATCTGGCCCGATGCCGAGGGTCATCTGGCCCGCCATGCCGCGCAGACCAA
TATCCCCTATGGGCTCTCGACGGTGGCAAGCCAAAGCCCCGAGGATCTGGCCCCGCATCTGGGCGCGCAGGGCTGGTTCC
AGATGTATCCGCCCAAAGATGAAGGCATCCGCAAGGACATGCTGGAGCGTGCGCGGGCGGCGGGTTTCAAGGTGCTGGTG
CTGACAGTCGATGTGCCGGTGGCGTCGCGCCGGGAGCGGCAGACCCGCTCGGGGCTGACGCAGCCGCCGCGTCTGACACC
GCGCCTGCTGGCGCAGGTGGCGATCCGCCCGGCGTGGGCGCTGGGGATGGCGCGGCAGCATCGCGGCGAAGGGGGCATGC
CGCATATGCGCACCCTTGATAAATACATCGAGGGCGCGGCCTCGGCTTTGTCCTCTACCGCCCATATTGGCTATTTGCTG
CGGACTGCGCCCGATTGGGCGTACCTTGAATGGCTGCGCGATCATTGGGAGGGGCCGCTGGTGGTCAAGGGCGTTCTGGA
TGCGTGCGACGCGCCCCGGCTGGAGGCGGCAGGGGCTGATGCGATCTGGATCTCCAACCACGCGGGCCGTCAGTTTGATG
CGGCCCCTGCCCCGATCGAGGTGCTCGAGGACATCCGTGCGGCCACCACCCTGCCGCTGATCCTCGACAGTGGTATCGAG
GGCGGGCTTGATATTTTGCGCGCGCTGGCGCTCGGGGCTGATTTTGTGATGCTGGGTCGGGCCTGGCATTATGCGCTTGC
AGCATTGGGCGCGGCCGGCCCTGCACATCTGCACGACATCCTGAGCAAAGATCTGACCGCCAACATGGGCCAGCTTGGCA
TCCGTACCCTGGCAGAGGTGCGCGACCTGAAGCGGCTCAGCCTCGACTAA

Upstream 100 bases:

>100_bases
CCCCATAGAGAGCCAAACCGCCGAGACTCATCCGGCGCAGATGTCTTTGTGCGGTCTTCCCCGCGCAAAGGGGATAGACA
GCGCCAGCGTTTTGCAAATG

Downstream 100 bases:

>100_bases
AGGCGGCTCGATCAAAGGCAGCGTGCCGCAAAGGACCGCGCGGTGCGCGCCAAAAAGCGAGGGCGCAGCCCTCTGGACCG
CGCCCTGCGTCTGTCCCCCC

Product: L-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAGMTLDQRYPALDDLRAKARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILGGPQEVDLGTTLFGTPLPRPF
GIAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSPEDLAPHLGAQGWFQMYPPKDEGIRKDMLERARAAGFKVLV
LTVDVPVASRRERQTRSGLTQPPRLTPRLLAQVAIRPAWALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLL
RTAPDWAYLEWLRDHWEGPLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIEVLEDIRAATTLPLILDSGIE
GGLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDILSKDLTANMGQLGIRTLAEVRDLKRLSLD

Sequences:

>Translated_389_residues
MAGMTLDQRYPALDDLRAKARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILGGPQEVDLGTTLFGTPLPRPF
GIAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSPEDLAPHLGAQGWFQMYPPKDEGIRKDMLERARAAGFKVLV
LTVDVPVASRRERQTRSGLTQPPRLTPRLLAQVAIRPAWALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLL
RTAPDWAYLEWLRDHWEGPLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIEVLEDIRAATTLPLILDSGIE
GGLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDILSKDLTANMGQLGIRTLAEVRDLKRLSLD
>Mature_388_residues
AGMTLDQRYPALDDLRAKARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILGGPQEVDLGTTLFGTPLPRPFG
IAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSPEDLAPHLGAQGWFQMYPPKDEGIRKDMLERARAAGFKVLVL
TVDVPVASRRERQTRSGLTQPPRLTPRLLAQVAIRPAWALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLLR
TAPDWAYLEWLRDHWEGPLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIEVLEDIRAATTLPLILDSGIEG
GLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDILSKDLTANMGQLGIRTLAEVRDLKRLSLD

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=382, Percent_Identity=30.8900523560209, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI7705393, Length=382, Percent_Identity=30.8900523560209, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI11068137, Length=374, Percent_Identity=28.3422459893048, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1790033, Length=375, Percent_Identity=38.1333333333333, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193208036, Length=378, Percent_Identity=31.2169312169312, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32566217, Length=297, Percent_Identity=29.6296296296296, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323587, Length=389, Percent_Identity=29.0488431876607, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI281363140, Length=374, Percent_Identity=33.4224598930481, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI78707190, Length=374, Percent_Identity=33.4224598930481, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI78707188, Length=374, Percent_Identity=33.4224598930481, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42280; Mature: 42149

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGMTLDQRYPALDDLRAKARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPQEVDLGTTLFGTPLPRPFGIAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSP
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCC
EDLAPHLGAQGWFQMYPPKDEGIRKDMLERARAAGFKVLVLTVDVPVASRRERQTRSGLT
HHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCC
QPPRLTPRLLAQVAIRPAWALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAPDWAYLEWLRDHWEGPLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIE
HCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHH
VLEDIRAATTLPLILDSGIEGGLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSKDLTANMGQLGIRTLAEVRDLKRLSLD
HHHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGMTLDQRYPALDDLRAKARTRLPRFVWEYLDSATGREATQARNRLCLDRIGLMPAILG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
GPQEVDLGTTLFGTPLPRPFGIAPVGMSGLIWPDAEGHLARHAAQTNIPYGLSTVASQSP
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCC
EDLAPHLGAQGWFQMYPPKDEGIRKDMLERARAAGFKVLVLTVDVPVASRRERQTRSGLT
HHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCC
QPPRLTPRLLAQVAIRPAWALGMARQHRGEGGMPHMRTLDKYIEGAASALSSTAHIGYLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAPDWAYLEWLRDHWEGPLVVKGVLDACDAPRLEAAGADAIWISNHAGRQFDAAPAPIE
HCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHH
VLEDIRAATTLPLILDSGIEGGLDILRALALGADFVMLGRAWHYALAALGAAGPAHLHDI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSKDLTANMGQLGIRTLAEVRDLKRLSLD
HHHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA