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The map label for this gene is rpiA

Identifier: 99081800

GI number: 99081800

Start: 2064158

End: 2064946

Strand: Reverse

Name: rpiA

Synonym: TM1040_1960

Alternate gene names: 99081800

Gene position: 2064946-2064158 (Counterclockwise)

Preceding gene: 99081803

Following gene: 99081798

Centisome position: 64.51

GC content: 61.85

Gene sequence:

>789_bases
ATGAGCGGCGATCTATCCCCCATCGACAAGGCGAAATTCGTGGCTGCCAAACGCGCGGCAGAGCTGGTGGAGGACGGCAT
GCGTGTCGGACTGGGCACCGGGTCCACCGCCGCGTGGCTGGTGCGGTGTCTTGGCGAAATGGTGCGCGAGGACGGGCTCA
AGATCACCGGCGTGCCGACCTCTGCCCGTACCGCCGAGCTGGCGCGCGAGGTCGGGATTGAGCTGATCACCCTGGATGAG
GCGCGCTGGCTCGACCTCACGATTGACGGTGCGGATGAATTCGACAGCGAACTCAATCTCATCAAGGGCGGGGGAGGCGC
GCTCTTGCAGGAAAAGATCGTCGCGACGGCCTCCGATCAGATGGTGGTGATCGCCGACAAGGCCAAGGAAGTGGAGACGC
TGGGGGCCTTCCCGCTGCCCATCGAGGTAATCCCCTTTGGCTGGCAGACCTCGCAGGCGCTGGTGGAAGAGACGCTGATC
TCGATGGATGTAATGGGGCGCAGCTCGACGTTGCGGATGAATGGTGCCAGCCCCTATGTGACCGACGAGGGCAATCACAT
CCTTGATCTGCATCTCAACCGGATCGGCAATCCGCGCCAGCTGGCGTTGGTGCTGAACCAGATCCCCGGCGTGGTTGAGA
ACGGGCTGTTCATCGACATCTGCGACACGGTGGTGATCGGCTATGGCGATGGCAAGGTCGAGGTGCGCGACATCAACGAG
GGCACTATCGAGACGGACCGGATCGATTTTGTCGAGACCGACAATCTCTTTGCGGATTTGAACGACTGA

Upstream 100 bases:

>100_bases
CCCTCGCGCGAGACTTGGAAAGCGCCTATAACGGGCGGGCTGGCAGCGGGCGGTTTGTCCAGACGCCATGCCACATCCAA
AAATGCGGAGGTCCATTCCC

Downstream 100 bases:

>100_bases
AGGCAGATACGCCGCCCCCAGGTTTAGGGCGGCTCTCTGTGTGCTCTGGTGGGGGCGCCGCAGCCTAGTGTTGCGCGGCG
TGGTCCTCCTGCCATTCTTT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSGDLSPIDKAKFVAAKRAAELVEDGMRVGLGTGSTAAWLVRCLGEMVREDGLKITGVPTSARTAELAREVGIELITLDE
ARWLDLTIDGADEFDSELNLIKGGGGALLQEKIVATASDQMVVIADKAKEVETLGAFPLPIEVIPFGWQTSQALVEETLI
SMDVMGRSSTLRMNGASPYVTDEGNHILDLHLNRIGNPRQLALVLNQIPGVVENGLFIDICDTVVIGYGDGKVEVRDINE
GTIETDRIDFVETDNLFADLND

Sequences:

>Translated_262_residues
MSGDLSPIDKAKFVAAKRAAELVEDGMRVGLGTGSTAAWLVRCLGEMVREDGLKITGVPTSARTAELAREVGIELITLDE
ARWLDLTIDGADEFDSELNLIKGGGGALLQEKIVATASDQMVVIADKAKEVETLGAFPLPIEVIPFGWQTSQALVEETLI
SMDVMGRSSTLRMNGASPYVTDEGNHILDLHLNRIGNPRQLALVLNQIPGVVENGLFIDICDTVVIGYGDGKVEVRDINE
GTIETDRIDFVETDNLFADLND
>Mature_261_residues
SGDLSPIDKAKFVAAKRAAELVEDGMRVGLGTGSTAAWLVRCLGEMVREDGLKITGVPTSARTAELAREVGIELITLDEA
RWLDLTIDGADEFDSELNLIKGGGGALLQEKIVATASDQMVVIADKAKEVETLGAFPLPIEVIPFGWQTSQALVEETLIS
MDVMGRSSTLRMNGASPYVTDEGNHILDLHLNRIGNPRQLALVLNQIPGVVENGLFIDICDTVVIGYGDGKVEVRDINEG
TIETDRIDFVETDNLFADLND

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=239, Percent_Identity=39.3305439330544, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=38.3928571428571, Blast_Score=131, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17551758, Length=240, Percent_Identity=40.4166666666667, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324669, Length=245, Percent_Identity=33.0612244897959, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281364072, Length=225, Percent_Identity=35.1111111111111, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_SILST (Q1GF74)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613954.1
- ProteinModelPortal:   Q1GF74
- SMR:   Q1GF74
- STRING:   Q1GF74
- GeneID:   4077144
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1960
- NMPDR:   fig|292414.1.peg.346
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- PhylomeDB:   Q1GF74
- ProtClustDB:   PRK00702
- BioCyc:   SSP292414:TM1040_1960-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 28239; Mature: 28108

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDLSPIDKAKFVAAKRAAELVEDGMRVGLGTGSTAAWLVRCLGEMVREDGLKITGVPT
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCC
SARTAELAREVGIELITLDEARWLDLTIDGADEFDSELNLIKGGGGALLQEKIVATASDQ
CHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHEECCCC
MVVIADKAKEVETLGAFPLPIEVIPFGWQTSQALVEETLISMDVMGRSSTLRMNGASPYV
EEEEECCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
TDEGNHILDLHLNRIGNPRQLALVLNQIPGVVENGLFIDICDTVVIGYGDGKVEVRDINE
ECCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEEECEEEEECCCCEEEEEECCC
GTIETDRIDFVETDNLFADLND
CCEECCCEEEEECCCEEEECCC
>Mature Secondary Structure 
SGDLSPIDKAKFVAAKRAAELVEDGMRVGLGTGSTAAWLVRCLGEMVREDGLKITGVPT
CCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCC
SARTAELAREVGIELITLDEARWLDLTIDGADEFDSELNLIKGGGGALLQEKIVATASDQ
CHHHHHHHHHHCCEEEEECCCEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHEECCCC
MVVIADKAKEVETLGAFPLPIEVIPFGWQTSQALVEETLISMDVMGRSSTLRMNGASPYV
EEEEECCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
TDEGNHILDLHLNRIGNPRQLALVLNQIPGVVENGLFIDICDTVVIGYGDGKVEVRDINE
ECCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEEECEEEEECCCCEEEEEECCC
GTIETDRIDFVETDNLFADLND
CCEECCCEEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA