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The map label for this gene is yciL [C]

Identifier: 99081768

GI number: 99081768

Start: 2026097

End: 2027365

Strand: Direct

Name: yciL [C]

Synonym: TM1040_1927

Alternate gene names: 99081768

Gene position: 2026097-2027365 (Clockwise)

Preceding gene: 99081762

Following gene: 99081769

Centisome position: 63.3

GC content: 64.78

Gene sequence:

>1269_bases
ATGCTTTCGCCGCTCTCGCGAATAGGCTATGGCAGCGCCATGAGCAAGAAAACCCCATCCAAACCGCCCGCGCGCCGCGC
CGCCAACGCTGCCCGGCCAAAGGCCACCCCCTCCGCGACGCCGCGCGCACACAAGGGCCTGCAGGCAGGCGCACCCGCAG
ACGCGCGGCCCTCGCAAGACGGTGACCGCATCGCCAAGGTGCTGTCGCGCGCAGGCGTGGCCTCTCGTCGCGAGGCGGAA
CGGATGATTGCGGAGGGTCGCGTTGCGGTCAATGGCAAGGTCATCGACAGCCCCGCGCTCAATGTGACCAATCTGGATCG
CATCGTGGTGGATGGCAATCCGCTGCCCGAGGCCGAGGCCCCGCGGCTTTGGCTCTATTACAAGCCCAACGGGTTGGTCA
CCACGACCTCCGACGAGAAAGGGCGCAAGACGATCTTTGACGCATTGCCCGAGGACCTGCCGCGGGTGATGACAGTGGGC
CGGCTTGACCTCAATTCCGAAGGCCTGCTGCTGCTGACCAACGACGGCGGCGTCAAACGCCAGTTGGAGCTGCCCTCGAC
AGGCTGGCTACGCCGCTACCGCGTGCGGATCAATGGCCGCCCGCAGGATCATGAATTTGACGTGCTGCGCAAAGGCGTGG
TGATCGACGGCGAGCGTTTTCAGCCGATGACCATCTCGCTCGATCGCCAGCAAGGCGCCAACGCATGGCTCACCATCGGG
CTGCGCGAAGGCAAGAACCGCGAAATTCGCCGCGCCATGGAAGAGGTTGGCTATCCGGTAAACCGGCTTCTGCGGATCTC
TTATGGGCCGTTCCAGCTCGGCACGCTCAAGGAAGGCGAAGTAGAGGAGTTGCGCCCACGCGTGGTGCGGGATCAACTGG
GTCTCGCCGCACCCGAAGGGGATGGCGAAGCCAAGAAGAAACCCACCCGCCCCGGACGCGGCCCGCGCAATCCTGGCGCA
AAGACTGCTGGAAAAGGCATCGGCGCGCCCAACGCTCGCCCGACAGGTAAAGGCGCAGTCAAAGCCCCCGAAGGCAGAGT
TTTTTCTGGCAAGACCTTCTCGGGCAAAACCACCGGCAAAACCGCTGGCAAACCTGCGGCTCATAAGGGCCAGGGCGGCA
AACCCTCGGGTCCCAAGAGTTTTGGGACCAAACAGGGCGGCGGCTCGGGCGCGCGAGGATCCGGTAAACCCAATGGCGCA
TCCGGTGGGGCATCCGGCGGCAAATTCAGCCCCGGCGGGCGCCGTTTTGGCAAAAAACCGCAGGACTGA

Upstream 100 bases:

>100_bases
TCCACCTCTGCGTTGCTCCTTTTGTCGCCCGTTCCAATGCCCGTTGGCACGCTCCGGCCCCATCATCGCGGGACGTCCGT
GCGGCTGGCCGGTGTAATGG

Downstream 100 bases:

>100_bases
GCCCCCCTTGCCGGACTTCCCCCTAGCAGGAGCGCCTGCAATCTCCTAGGTTTCAAGAGGTTGGGGAACGTTTTTGGGGG
CGAAAGAGGTGCAAACCGTC

Product: pseudouridine synthase, Rsu

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLSPLSRIGYGSAMSKKTPSKPPARRAANAARPKATPSATPRAHKGLQAGAPADARPSQDGDRIAKVLSRAGVASRREAE
RMIAEGRVAVNGKVIDSPALNVTNLDRIVVDGNPLPEAEAPRLWLYYKPNGLVTTTSDEKGRKTIFDALPEDLPRVMTVG
RLDLNSEGLLLLTNDGGVKRQLELPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDGERFQPMTISLDRQQGANAWLTIG
LREGKNREIRRAMEEVGYPVNRLLRISYGPFQLGTLKEGEVEELRPRVVRDQLGLAAPEGDGEAKKKPTRPGRGPRNPGA
KTAGKGIGAPNARPTGKGAVKAPEGRVFSGKTFSGKTTGKTAGKPAAHKGQGGKPSGPKSFGTKQGGGSGARGSGKPNGA
SGGASGGKFSPGGRRFGKKPQD

Sequences:

>Translated_422_residues
MLSPLSRIGYGSAMSKKTPSKPPARRAANAARPKATPSATPRAHKGLQAGAPADARPSQDGDRIAKVLSRAGVASRREAE
RMIAEGRVAVNGKVIDSPALNVTNLDRIVVDGNPLPEAEAPRLWLYYKPNGLVTTTSDEKGRKTIFDALPEDLPRVMTVG
RLDLNSEGLLLLTNDGGVKRQLELPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDGERFQPMTISLDRQQGANAWLTIG
LREGKNREIRRAMEEVGYPVNRLLRISYGPFQLGTLKEGEVEELRPRVVRDQLGLAAPEGDGEAKKKPTRPGRGPRNPGA
KTAGKGIGAPNARPTGKGAVKAPEGRVFSGKTFSGKTTGKTAGKPAAHKGQGGKPSGPKSFGTKQGGGSGARGSGKPNGA
SGGASGGKFSPGGRRFGKKPQD
>Mature_422_residues
MLSPLSRIGYGSAMSKKTPSKPPARRAANAARPKATPSATPRAHKGLQAGAPADARPSQDGDRIAKVLSRAGVASRREAE
RMIAEGRVAVNGKVIDSPALNVTNLDRIVVDGNPLPEAEAPRLWLYYKPNGLVTTTSDEKGRKTIFDALPEDLPRVMTVG
RLDLNSEGLLLLTNDGGVKRQLELPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDGERFQPMTISLDRQQGANAWLTIG
LREGKNREIRRAMEEVGYPVNRLLRISYGPFQLGTLKEGEVEELRPRVVRDQLGLAAPEGDGEAKKKPTRPGRGPRNPGA
KTAGKGIGAPNARPTGKGAVKAPEGRVFSGKTFSGKTTGKTAGKPAAHKGQGGKPSGPKSFGTKQGGGSGARGSGKPNGA
SGGASGGKFSPGGRRFGKKPQD

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=218, Percent_Identity=40.3669724770642, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081838, Length=184, Percent_Identity=33.695652173913, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790453, Length=236, Percent_Identity=32.6271186440678, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788510, Length=204, Percent_Identity=28.4313725490196, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 44764; Mature: 44764

Theoretical pI: Translated: 11.39; Mature: 11.39

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPLSRIGYGSAMSKKTPSKPPARRAANAARPKATPSATPRAHKGLQAGAPADARPSQD
CCCCHHHHCCCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
GDRIAKVLSRAGVASRREAERMIAEGRVAVNGKVIDSPALNVTNLDRIVVDGNPLPEAEA
HHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCEEECCCCCCCCCCCEEEECCCCCCCCCC
PRLWLYYKPNGLVTTTSDEKGRKTIFDALPEDLPRVMTVGRLDLNSEGLLLLTNDGGVKR
CEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEECCCCCEE
QLELPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDGERFQPMTISLDRQQGANAWLTIG
EEECCCCCCEEEEEEEECCCCCCCHHHHHHCCEEECCCCCCCEEEEECCCCCCCEEEEEE
LREGKNREIRRAMEEVGYPVNRLLRISYGPFQLGTLKEGEVEELRPRVVRDQLGLAAPEG
ECCCCCHHHHHHHHHHCCCHHHEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
DGEAKKKPTRPGRGPRNPGAKTAGKGIGAPNARPTGKGAVKAPEGRVFSGKTFSGKTTGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCCCCCCCCCCC
TAGKPAAHKGQGGKPSGPKSFGTKQGGGSGARGSGKPNGASGGASGGKFSPGGRRFGKKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCC
QD
CC
>Mature Secondary Structure
MLSPLSRIGYGSAMSKKTPSKPPARRAANAARPKATPSATPRAHKGLQAGAPADARPSQD
CCCCHHHHCCCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
GDRIAKVLSRAGVASRREAERMIAEGRVAVNGKVIDSPALNVTNLDRIVVDGNPLPEAEA
HHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCEEECCCCCCCCCCCEEEECCCCCCCCCC
PRLWLYYKPNGLVTTTSDEKGRKTIFDALPEDLPRVMTVGRLDLNSEGLLLLTNDGGVKR
CEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEECCCCCEE
QLELPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDGERFQPMTISLDRQQGANAWLTIG
EEECCCCCCEEEEEEEECCCCCCCHHHHHHCCEEECCCCCCCEEEEECCCCCCCEEEEEE
LREGKNREIRRAMEEVGYPVNRLLRISYGPFQLGTLKEGEVEELRPRVVRDQLGLAAPEG
ECCCCCHHHHHHHHHHCCCHHHEEEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
DGEAKKKPTRPGRGPRNPGAKTAGKGIGAPNARPTGKGAVKAPEGRVFSGKTFSGKTTGK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCCCCCCCCCCC
TAGKPAAHKGQGGKPSGPKSFGTKQGGGSGARGSGKPNGASGGASGGKFSPGGRRFGKKP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCC
QD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA