Click here to switch to the map view.

The map label for this gene is dtd

Identifier: 99081660

GI number: 99081660

Start: 1913416

End: 1913886

Strand: Direct

Name: dtd

Synonym: TM1040_1819

Alternate gene names: 99081660

Gene position: 1913416-1913886 (Clockwise)

Preceding gene: 99081659

Following gene: 99081661

Centisome position: 59.78

GC content: 57.75

Gene sequence:

>471_bases
ATGCGTGCCCTCCTGCAACGTGTCAGCGCCGCCAGTGTCACCGTCGACAATGCGGTTATTGGCGAAATCGGCCCCGGTCT
TTTGGTCTTTGTCTGTGCCATGCGCGGAGATTCTGAGGCCGAGGCCACCCAACTGGTGCAAAAAATTGCGCGTCTGCGGA
TTTTTCGAGACGACGCGGGCAAAATGAACCGCTCGGTCAGCGATACCAGCGGCGCCGTTCTTGTGGTCAGCCAGTTCACC
CTGGGCGCCGACACGCGCAGCGGTACCCGTCCGGGCTTTTCCAAAGCAGCTGCACCGGATGAGGGAATGCGGCTTTATCA
TTGTTTTTGCGCGAAAATGCGTGAGACTGGGCTTACAGTGCAAACAGGAGAATTCGGCGCTGACATGAAAGTTTCACTTG
TGAACGATGGTCCTGTTACGCTCTGGCTGGACACAGATGACCGTCGCAACACGTCAGCCGGATCGGGGTAG

Upstream 100 bases:

>100_bases
CTCATGGGACTGGCCCGAGGGATCACGGCCGCGACAATGCCCGTCGCGCGCTGGCCCGCTGTGCCCACCCCGCCCATGAT
TCTAGTCTGAGAGGATAGGC

Downstream 100 bases:

>100_bases
AAACCCCGCATGAGCCGGAAAATTGCGGGCCAAGCGTCAGAGCATTCCCCCTGTTTTGGGCGCCTGACACAGATGCGCGC
GCAATTTTCTATCATTATTC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAGKMNRSVSDTSGAVLVVSQFT
LGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTVQTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG

Sequences:

>Translated_156_residues
MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAGKMNRSVSDTSGAVLVVSQFT
LGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTVQTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG
>Mature_156_residues
MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAGKMNRSVSDTSGAVLVVSQFT
LGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTVQTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=38.5135135135135, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=54.5454545454545, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=39.7350993377483, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=149, Percent_Identity=41.6107382550336, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281361569, Length=153, Percent_Identity=37.9084967320261, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SILST (Q1GFL4)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613814.1
- ProteinModelPortal:   Q1GFL4
- SMR:   Q1GFL4
- STRING:   Q1GFL4
- GeneID:   4076965
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1819
- NMPDR:   fig|292414.1.peg.207
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q1GFL4
- ProtClustDB:   PRK05273
- BioCyc:   SSP292414:TM1040_1819-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16587; Mature: 16587

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAG
CHHHHHHHHHHHEEECCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCH
KMNRSVSDTSGAVLVVSQFTLGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTV
HHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
QTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG
EECCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRALLQRVSAASVTVDNAVIGEIGPGLLVFVCAMRGDSEAEATQLVQKIARLRIFRDDAG
CHHHHHHHHHHHEEECCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCH
KMNRSVSDTSGAVLVVSQFTLGADTRSGTRPGFSKAAAPDEGMRLYHCFCAKMRETGLTV
HHCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE
QTGEFGADMKVSLVNDGPVTLWLDTDDRRNTSAGSG
EECCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA