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The map label for this gene is yafC [H]

Identifier: 99081589

GI number: 99081589

Start: 1841365

End: 1842276

Strand: Reverse

Name: yafC [H]

Synonym: TM1040_1748

Alternate gene names: 99081589

Gene position: 1842276-1841365 (Counterclockwise)

Preceding gene: 99081591

Following gene: 99081587

Centisome position: 57.55

GC content: 58.77

Gene sequence:

>912_bases
ATGCATTTATGCATGAACTGGAGTGCAATCAACTTTGACTGGAACCAGGTGAGATCCTTTCTGGCGACTGCCGAGGAAGG
CTCGTTCTCGGCTGCCGCGCGCGTGCTGAACCAGACGCAGCCGACCGTGGGCCGTCAGGTTGGCGCACTCGAGGAGGCGC
TTGGGGTCACCGTGTTTGAGCGTGTCGGCAAGTCGCTCCGACTTACGACGGCGGGTACGGAGCTATTGGTCCATGTCCGG
GAGATGGCGGATGTCGCGAACAAGATTTCGCTGACTGCAACCGGCCAGTCGCAATCTGTCGAAGGGCAGGTCAGGATCAC
CGCGTCCGATGTGATGTCGACCTATCAACTGCCTGCCATGCTCAAACAGATCAGGCTTGCGGCGCCCCGGCTCGAAATCG
ACGTGGTTGCCGCCAATGATCTCCGGGACCTTCACCGGCGCGAGGCCGACATCGCGATCCGGCACATCCGCCCGACGCAG
CCGGATTTGATCGCGCGGCTTGTGGCGCAGGCGAGCGCGCATCTCTATGCGGCTTCCTCCTATCTGGATCAGGTCGGACG
GCCCAGAAGCGAGGAAGAGCTGGCTCAGTTGGACTTTGTCAGCTTTGGCGATGTCGAGAGGTTCATCGGGTTTCTCAATC
CGGCGGGCATTCCGGTAACGCGCAAAAATTTCCGTATCGGATCGCACAGCGGGGTCGTGTCATGGGAACTGGTGCGCCAA
GGCTTTGGCGTTAGTGTCATGTCAGATGATGTAGCAGCCCCAACCCCCGGAATTGAGAGAATTTTGCCGGACCGAGATCC
TTTTGCGTTTCCGATTTGGCTGGCAACCCATTCAGAGCTGCACACCGCACGTCGGATCAGGCTGGTTTTTGACCAATTGG
CCGAGCAATTTAAGGCGAGAGAAACCTCTTAA

Upstream 100 bases:

>100_bases
TTGAAGAAGCGGCCATATCTCTACTTTCCGTTTGTGGTGTCAGAGCAACCTTTACATCCAAACACAGTTTTATGGAATTG
ATCCGCTTTGCAGGATGGTT

Downstream 100 bases:

>100_bases
GGCACTCGTTTGGCGCAGAGTTCCGCACTTCGGGGGCCCCTCGAGCCGGCTATATACCCATGTTCGGCTCGCACGCCGGA
TGCGGACGACGCGCCTGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MHLCMNWSAINFDWNQVRSFLATAEEGSFSAAARVLNQTQPTVGRQVGALEEALGVTVFERVGKSLRLTTAGTELLVHVR
EMADVANKISLTATGQSQSVEGQVRITASDVMSTYQLPAMLKQIRLAAPRLEIDVVAANDLRDLHRREADIAIRHIRPTQ
PDLIARLVAQASAHLYAASSYLDQVGRPRSEEELAQLDFVSFGDVERFIGFLNPAGIPVTRKNFRIGSHSGVVSWELVRQ
GFGVSVMSDDVAAPTPGIERILPDRDPFAFPIWLATHSELHTARRIRLVFDQLAEQFKARETS

Sequences:

>Translated_303_residues
MHLCMNWSAINFDWNQVRSFLATAEEGSFSAAARVLNQTQPTVGRQVGALEEALGVTVFERVGKSLRLTTAGTELLVHVR
EMADVANKISLTATGQSQSVEGQVRITASDVMSTYQLPAMLKQIRLAAPRLEIDVVAANDLRDLHRREADIAIRHIRPTQ
PDLIARLVAQASAHLYAASSYLDQVGRPRSEEELAQLDFVSFGDVERFIGFLNPAGIPVTRKNFRIGSHSGVVSWELVRQ
GFGVSVMSDDVAAPTPGIERILPDRDPFAFPIWLATHSELHTARRIRLVFDQLAEQFKARETS
>Mature_303_residues
MHLCMNWSAINFDWNQVRSFLATAEEGSFSAAARVLNQTQPTVGRQVGALEEALGVTVFERVGKSLRLTTAGTELLVHVR
EMADVANKISLTATGQSQSVEGQVRITASDVMSTYQLPAMLKQIRLAAPRLEIDVVAANDLRDLHRREADIAIRHIRPTQ
PDLIARLVAQASAHLYAASSYLDQVGRPRSEEELAQLDFVSFGDVERFIGFLNPAGIPVTRKNFRIGSHSGVVSWELVRQ
GFGVSVMSDDVAAPTPGIERILPDRDPFAFPIWLATHSELHTARRIRLVFDQLAEQFKARETS

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=26.9360269360269, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87082132, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788626, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789440, Length=282, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790208, Length=263, Percent_Identity=26.615969581749, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=264, Percent_Identity=26.8939393939394, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=110, Percent_Identity=35.4545454545455, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33540; Mature: 33540

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLCMNWSAINFDWNQVRSFLATAEEGSFSAAARVLNQTQPTVGRQVGALEEALGVTVFE
CEEEEECEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RVGKSLRLTTAGTELLVHVREMADVANKISLTATGQSQSVEGQVRITASDVMSTYQLPAM
HCCCCEEEEECHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHH
LKQIRLAAPRLEIDVVAANDLRDLHRREADIAIRHIRPTQPDLIARLVAQASAHLYAASS
HHHHHHHCCCEEEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YLDQVGRPRSEEELAQLDFVSFGDVERFIGFLNPAGIPVTRKNFRIGSHSGVVSWELVRQ
HHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCEECCCEEECCCCCCEEHHHHHC
GFGVSVMSDDVAAPTPGIERILPDRDPFAFPIWLATHSELHTARRIRLVFDQLAEQFKAR
CCCCEEECCCCCCCCCCHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
ETS
CCC
>Mature Secondary Structure
MHLCMNWSAINFDWNQVRSFLATAEEGSFSAAARVLNQTQPTVGRQVGALEEALGVTVFE
CEEEEECEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RVGKSLRLTTAGTELLVHVREMADVANKISLTATGQSQSVEGQVRITASDVMSTYQLPAM
HCCCCEEEEECHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHH
LKQIRLAAPRLEIDVVAANDLRDLHRREADIAIRHIRPTQPDLIARLVAQASAHLYAASS
HHHHHHHCCCEEEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
YLDQVGRPRSEEELAQLDFVSFGDVERFIGFLNPAGIPVTRKNFRIGSHSGVVSWELVRQ
HHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCEECCCEEECCCCCCEEHHHHHC
GFGVSVMSDDVAAPTPGIERILPDRDPFAFPIWLATHSELHTARRIRLVFDQLAEQFKAR
CCCCEEECCCCCCCCCCHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHC
ETS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]