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The map label for this gene is putA [H]

Identifier: 99081536

GI number: 99081536

Start: 1789603

End: 1793010

Strand: Direct

Name: putA [H]

Synonym: TM1040_1695

Alternate gene names: 99081536

Gene position: 1789603-1793010 (Clockwise)

Preceding gene: 99081533

Following gene: 99081537

Centisome position: 55.91

GC content: 62.97

Gene sequence:

>3408_bases
ATGACTCGTGATATGCGCCTACGCGACCGGATTGATGCCGGCACCTATTTGGATCAGGCCAATATGCGCGATGCGCTGGT
GGCTCTGGCCGCTCTGTCCGAAGCGGATCGCTCCGCCATCTGTGCCTCGGCCACCCAATTGGTGAAAGACATCCGTGGCC
ATTCCTCGCCCGGCTTGATGGAAGTGTTCCTCGCCGAATATGGCCTATCGACCGACGAAGGCGTGGCCCTCATGTGCCTC
GCAGAAGCGCTCTTGCGGGTGCCGGATGCGGACACCATCGATGCGCTCATCGAAGACAAGATCGCCCCCTCCGATTGGGG
TAAGCACATGGGCAAGTCGACCTCCTCTCTGGTCAATGCCTCCACTTGGGCGCTGATGCTGACGGGCAAGGTTCTGGACG
AGGAAAAGAGCCCCGTCGGCGCGCTGCGTGGGGCCATCAAACGGCTGGGCGAGCCGGTGATCCGCACCGCCGTGGGCCGC
GCCATGAAGGAAATGGGCCGTCAGTTTGTTCTTGGGGAGACCATCGAGAGTGCGATGAAACGCGCGTCGAACATGGAAGC
CAAGGGCTATACCTATTCCTACGACATGCTGGGCGAGGCTGCGCGTACCGAGGCAGACGCCTCGCGCTATCACCTGGCCT
ATTCCCGCGCGATTTCGGCCATTGCCAGCGCCTGCACCAGCACCGACATCCGCGAAAACCCCGGCATCTCGGTCAAACTC
TCGGCGCTGCATCCACGCTACGAGATCGCCAAGGAAGAGTCCGTCATGCAACAGCTGGTGCCGCGTCTGAAGGCACTGGC
GCTTCTGGCCAAGGCGGCCAAGATGGGGCTCAACATCGACGCCGAAGAAGCTGATCGCCTGTCGCTGTCGCTCGAAGTGA
TCGAAGAAGTGATCTCTGACCCCGCGCTCAAGGGTTGGGACGGTTTTGGCGTGGTGGTGCAGGCTTATGGGCCCCGCACC
GGGCTGGCGATTGATGCCCTTTATGAGATGGCCGAAAAATACGACCGCCGCTTTATGGTTCGCCTGGTAAAAGGCGCCTA
CTGGGACACCGAGATCAAGCGCGCTCAGGTTGAAGGCATGGACGGTTTCCCGGTCTTCACCTCCAAGGCGCTGACGGATG
TGTCCTACATCGCCAATGCACGCAAACTCCTGTCGCGCACCGATCGGATCTATCCGCAGTTTGCCACCCACAACGCCCAC
ACCGTCAGCGCCATTCTGCATATGGCCGAAGAAGGTCAGGCCTATGAGTTCCAGCGCTTGCACGGCATGGGCGAAACCCT
GCACCAGATGGTGATGGACCAGAACAAGACGCGCTGCCGGATCTACGCGCCAGTGGGCGCGCATCGCGATCTTCTGGCCT
ATCTGGTGCGTCGCCTGCTGGAAAACGGTGCGAACTCTTCTTTTGTGAACCAGATCGTTGACGAGGACGTACCACCGCAA
GTGGTGGCAGCTGATCCGTTCCAGGAGGTCGATGACCTGACAACCGATATCCCCACCGGCCCCAATCTGTTCCAGCCCGA
GCGCATCAACTCCAAAGGGTTTGATCTGCGTCACGCGCCAACCTTGGCCGCAATCGAGAAGGCCCGCGCGCCCTTCCGGG
AGGCCACCTGGGACGCGGTTCCGCTGATCGCGGGCGAAGCACAGCCCGAGGCCCGCGTTGCGGTCACAAACCCAAGCGAT
CTCAGTGAAATCGGCAGCGTGTCTCAATCCAGTGCCGAAGACGTGGAACTGGCGCTTGCCTCGGCCAACACCTGGGACGC
CCCCGCTGAGGAGCGCGCCGCCGCACTGAACAAGGCGGCTGACCTCTATGAGGCGCATTACGGCGAGCTCTTTGCGCTCT
TGGCCCGTGAGGCCGGCAAAACCCAGATGGATGCCGTCGCAGAGCTGCGCGAAGCGGTGGACTTCCTGCGCTATTATGCC
TCCCGCATCCCGGATGCAGCGCCAGCGGGTATCTTCACCTGCATCTCACCCTGGAACTTCCCGCTCGCGATCTTCACCGG
GCAGGTTTCGGCTGCGCTTGCCACGGGCAATGCGGTGCTGGCAAAACCTGCGGACCAGACCCCGCTGGTGGCCTTCCGCG
CCGTGGAACTGCTGCATGAGGCAGGTGTTCCACGCGATGTGCTGCAGTTCCTCCCCGGGCGCGGCTCCAAGGTTGGCGCA
GCCATCACGGGTGATGCACGCATCAACGGCGTTGCGTTTACCGGCTCCACCGCAACCGCCATGCGGATCCGCTCGGCCAT
GGCCGAGCATTGCGCCCCCGGCACGCCTCTCATTGCAGAGACAGGCGGTCTAAATGCGATGATCGTTGATTCAACCGCGC
TGCCCGAACAAGCGGTGCAGGCCGTGGTCGAAAGCGCGTTTCAGTCTGCAGGCCAGCGTTGCTCGGCGCTGCGCTGCCTC
TACCTGCAGGAGGACGTGGCCGAAGACGTGCTGACGATGCTTAAAGGCGCGATGGAGCTCCTTGATCTTGATGATCCCTG
GCATCTTGCGACCGACAGCGGCCCGGTGATCGACGAAGGATCACGCGCCAAGATCCTCGCCCATATCGACGAGGCCCGCG
CTGAGGGGCGCGTCCTGAAGGAAATGCAGGCGCCACAGAGCGGCACCTTTGTGGCGCCGACAATGATTTCGATCAACGGG
ATCAGCGACCTCAAGGAAGAGATCTTTGGCCCCGTCCTGCATGTCGCCACCTTCAAATCGCGCGAGCTTGATGCCGTGAT
CGACGCGATCAACGCCACGGGCTATGGGCTGACCTTCGGCCTGCAGACAAGAATTGATGACCGCGTACAGCACGTCTGCG
ACCGCATCCACGCGGGCAACATCTATGTGAACCGCAACCAGATCGGCGCTATTGTCGGCAGCCAACCCTTTGGGGGCGAA
GGCCTTTCCGGCACTGGTCCCAAAGCAGGCGGCCCGAACTACCTGGCCCGTTTCTGTGCTCCGGATCGCCGCCAGGTTGA
CGCCGCATGGAAAGACACCATGGGCGAGATCCCCGCGGCACGCGGCCAAGCCGGACATCCCGAAACCACCTCCCTGCCCG
GCCCCACAGGTGAATCAAACCGCCTCACGGTCTCGGCACGCCCGCCACTTCTCTGTGCGGGCCCCGGCGCCGAGGCCGTC
TCTGAACAGGCCAAACTGGTCGCGTCTCTGGGCGGCATCGCCATCGAGGCCGACGGCATGGTGGACCTGCACCGGCTGGC
GCATATGGATGGGATCTCTGGCGTTCTATGGTGGGGCGATGCGGACACGGGGCGCGAGATCGAACAGAGCCTCGCCAAAC
GTGAGGGACCGATTGTGCCGCTCATTCCCGGCGCGCCGGATCGCGCGCGGGTGCTCGCTGAACGCCATGTCTGTGTCGAC
ACCACGGCAGCCGGGGGCAACGCAGCCCTTCTGGGTGGCAACGCCTGA

Upstream 100 bases:

>100_bases
GCAAATAAGCGCATTTGACCTGTACTATTGCGACAATCGGGACAAATGACCAGTGATGACGCGATAAAAGGGGAAAAATC
TCTTAACAAGGGGAACACTC

Downstream 100 bases:

>100_bases
TCTGACAACGATGCGCTGCCCGGCCTCTGCGCCGGGCAGCACTTCTGCCCAAGCCTTTCATTTCGCTTGACCTCCCTGCG
CCGACGCCCCAGCTTCAGCG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1135; Mature: 1134

Protein sequence:

>1135_residues
MTRDMRLRDRIDAGTYLDQANMRDALVALAALSEADRSAICASATQLVKDIRGHSSPGLMEVFLAEYGLSTDEGVALMCL
AEALLRVPDADTIDALIEDKIAPSDWGKHMGKSTSSLVNASTWALMLTGKVLDEEKSPVGALRGAIKRLGEPVIRTAVGR
AMKEMGRQFVLGETIESAMKRASNMEAKGYTYSYDMLGEAARTEADASRYHLAYSRAISAIASACTSTDIRENPGISVKL
SALHPRYEIAKEESVMQQLVPRLKALALLAKAAKMGLNIDAEEADRLSLSLEVIEEVISDPALKGWDGFGVVVQAYGPRT
GLAIDALYEMAEKYDRRFMVRLVKGAYWDTEIKRAQVEGMDGFPVFTSKALTDVSYIANARKLLSRTDRIYPQFATHNAH
TVSAILHMAEEGQAYEFQRLHGMGETLHQMVMDQNKTRCRIYAPVGAHRDLLAYLVRRLLENGANSSFVNQIVDEDVPPQ
VVAADPFQEVDDLTTDIPTGPNLFQPERINSKGFDLRHAPTLAAIEKARAPFREATWDAVPLIAGEAQPEARVAVTNPSD
LSEIGSVSQSSAEDVELALASANTWDAPAEERAAALNKAADLYEAHYGELFALLAREAGKTQMDAVAELREAVDFLRYYA
SRIPDAAPAGIFTCISPWNFPLAIFTGQVSAALATGNAVLAKPADQTPLVAFRAVELLHEAGVPRDVLQFLPGRGSKVGA
AITGDARINGVAFTGSTATAMRIRSAMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQAVVESAFQSAGQRCSALRCL
YLQEDVAEDVLTMLKGAMELLDLDDPWHLATDSGPVIDEGSRAKILAHIDEARAEGRVLKEMQAPQSGTFVAPTMISING
ISDLKEEIFGPVLHVATFKSRELDAVIDAINATGYGLTFGLQTRIDDRVQHVCDRIHAGNIYVNRNQIGAIVGSQPFGGE
GLSGTGPKAGGPNYLARFCAPDRRQVDAAWKDTMGEIPAARGQAGHPETTSLPGPTGESNRLTVSARPPLLCAGPGAEAV
SEQAKLVASLGGIAIEADGMVDLHRLAHMDGISGVLWWGDADTGREIEQSLAKREGPIVPLIPGAPDRARVLAERHVCVD
TTAAGGNAALLGGNA

Sequences:

>Translated_1135_residues
MTRDMRLRDRIDAGTYLDQANMRDALVALAALSEADRSAICASATQLVKDIRGHSSPGLMEVFLAEYGLSTDEGVALMCL
AEALLRVPDADTIDALIEDKIAPSDWGKHMGKSTSSLVNASTWALMLTGKVLDEEKSPVGALRGAIKRLGEPVIRTAVGR
AMKEMGRQFVLGETIESAMKRASNMEAKGYTYSYDMLGEAARTEADASRYHLAYSRAISAIASACTSTDIRENPGISVKL
SALHPRYEIAKEESVMQQLVPRLKALALLAKAAKMGLNIDAEEADRLSLSLEVIEEVISDPALKGWDGFGVVVQAYGPRT
GLAIDALYEMAEKYDRRFMVRLVKGAYWDTEIKRAQVEGMDGFPVFTSKALTDVSYIANARKLLSRTDRIYPQFATHNAH
TVSAILHMAEEGQAYEFQRLHGMGETLHQMVMDQNKTRCRIYAPVGAHRDLLAYLVRRLLENGANSSFVNQIVDEDVPPQ
VVAADPFQEVDDLTTDIPTGPNLFQPERINSKGFDLRHAPTLAAIEKARAPFREATWDAVPLIAGEAQPEARVAVTNPSD
LSEIGSVSQSSAEDVELALASANTWDAPAEERAAALNKAADLYEAHYGELFALLAREAGKTQMDAVAELREAVDFLRYYA
SRIPDAAPAGIFTCISPWNFPLAIFTGQVSAALATGNAVLAKPADQTPLVAFRAVELLHEAGVPRDVLQFLPGRGSKVGA
AITGDARINGVAFTGSTATAMRIRSAMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQAVVESAFQSAGQRCSALRCL
YLQEDVAEDVLTMLKGAMELLDLDDPWHLATDSGPVIDEGSRAKILAHIDEARAEGRVLKEMQAPQSGTFVAPTMISING
ISDLKEEIFGPVLHVATFKSRELDAVIDAINATGYGLTFGLQTRIDDRVQHVCDRIHAGNIYVNRNQIGAIVGSQPFGGE
GLSGTGPKAGGPNYLARFCAPDRRQVDAAWKDTMGEIPAARGQAGHPETTSLPGPTGESNRLTVSARPPLLCAGPGAEAV
SEQAKLVASLGGIAIEADGMVDLHRLAHMDGISGVLWWGDADTGREIEQSLAKREGPIVPLIPGAPDRARVLAERHVCVD
TTAAGGNAALLGGNA
>Mature_1134_residues
TRDMRLRDRIDAGTYLDQANMRDALVALAALSEADRSAICASATQLVKDIRGHSSPGLMEVFLAEYGLSTDEGVALMCLA
EALLRVPDADTIDALIEDKIAPSDWGKHMGKSTSSLVNASTWALMLTGKVLDEEKSPVGALRGAIKRLGEPVIRTAVGRA
MKEMGRQFVLGETIESAMKRASNMEAKGYTYSYDMLGEAARTEADASRYHLAYSRAISAIASACTSTDIRENPGISVKLS
ALHPRYEIAKEESVMQQLVPRLKALALLAKAAKMGLNIDAEEADRLSLSLEVIEEVISDPALKGWDGFGVVVQAYGPRTG
LAIDALYEMAEKYDRRFMVRLVKGAYWDTEIKRAQVEGMDGFPVFTSKALTDVSYIANARKLLSRTDRIYPQFATHNAHT
VSAILHMAEEGQAYEFQRLHGMGETLHQMVMDQNKTRCRIYAPVGAHRDLLAYLVRRLLENGANSSFVNQIVDEDVPPQV
VAADPFQEVDDLTTDIPTGPNLFQPERINSKGFDLRHAPTLAAIEKARAPFREATWDAVPLIAGEAQPEARVAVTNPSDL
SEIGSVSQSSAEDVELALASANTWDAPAEERAAALNKAADLYEAHYGELFALLAREAGKTQMDAVAELREAVDFLRYYAS
RIPDAAPAGIFTCISPWNFPLAIFTGQVSAALATGNAVLAKPADQTPLVAFRAVELLHEAGVPRDVLQFLPGRGSKVGAA
ITGDARINGVAFTGSTATAMRIRSAMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQAVVESAFQSAGQRCSALRCLY
LQEDVAEDVLTMLKGAMELLDLDDPWHLATDSGPVIDEGSRAKILAHIDEARAEGRVLKEMQAPQSGTFVAPTMISINGI
SDLKEEIFGPVLHVATFKSRELDAVIDAINATGYGLTFGLQTRIDDRVQHVCDRIHAGNIYVNRNQIGAIVGSQPFGGEG
LSGTGPKAGGPNYLARFCAPDRRQVDAAWKDTMGEIPAARGQAGHPETTSLPGPTGESNRLTVSARPPLLCAGPGAEAVS
EQAKLVASLGGIAIEADGMVDLHRLAHMDGISGVLWWGDADTGREIEQSLAKREGPIVPLIPGAPDRARVLAERHVCVDT
TAAGGNAALLGGNA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=455, Percent_Identity=31.6483516483516, Blast_Score=194, Evalue=6e-49,
Organism=Homo sapiens, GI21361176, Length=451, Percent_Identity=32.5942350332594, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI25777736, Length=447, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI25777734, Length=447, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI238859541, Length=447, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI25777732, Length=446, Percent_Identity=32.2869955156951, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI25777724, Length=447, Percent_Identity=31.3199105145414, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777730, Length=446, Percent_Identity=31.8385650224215, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI21614513, Length=408, Percent_Identity=30.1470588235294, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI25777728, Length=405, Percent_Identity=32.5925925925926, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI238814322, Length=451, Percent_Identity=29.2682926829268, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI12007648, Length=455, Percent_Identity=29.010989010989, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25952152, Length=446, Percent_Identity=28.2511210762332, Blast_Score=140, Evalue=9e-33,
Organism=Homo sapiens, GI115387104, Length=439, Percent_Identity=26.1958997722096, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI4507229, Length=421, Percent_Identity=28.978622327791, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI188035924, Length=448, Percent_Identity=28.125, Blast_Score=134, Evalue=5e-31,
Organism=Homo sapiens, GI310128103, Length=448, Percent_Identity=28.125, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI310128093, Length=448, Percent_Identity=28.125, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI25777726, Length=447, Percent_Identity=27.2930648769575, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25777721, Length=434, Percent_Identity=27.8801843317972, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI310128091, Length=392, Percent_Identity=28.3163265306122, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI11095441, Length=408, Percent_Identity=26.7156862745098, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI71773324, Length=386, Percent_Identity=27.4611398963731, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI4502043, Length=407, Percent_Identity=26.7813267813268, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI238814371, Length=407, Percent_Identity=26.7813267813268, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI301500698, Length=275, Percent_Identity=29.0909090909091, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI310128089, Length=322, Percent_Identity=28.2608695652174, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI73695881, Length=325, Percent_Identity=25.8461538461538, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73695879, Length=325, Percent_Identity=25.8461538461538, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=28.3870967741935, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI206597441, Length=412, Percent_Identity=22.5728155339806, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI206597439, Length=412, Percent_Identity=22.5728155339806, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI22907049, Length=412, Percent_Identity=22.5728155339806, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128097, Length=254, Percent_Identity=30.3149606299213, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI310128087, Length=272, Percent_Identity=27.9411764705882, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI4557303, Length=330, Percent_Identity=22.1212121212121, Blast_Score=78, Evalue=6e-14,
Organism=Homo sapiens, GI73466520, Length=330, Percent_Identity=22.1212121212121, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI310128101, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=9e-12,
Organism=Homo sapiens, GI310128099, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787250, Length=1198, Percent_Identity=47.0784641068447, Blast_Score=960, Evalue=0.0,
Organism=Escherichia coli, GI87081896, Length=474, Percent_Identity=30.8016877637131, Blast_Score=189, Evalue=9e-49,
Organism=Escherichia coli, GI1789015, Length=468, Percent_Identity=32.6923076923077, Blast_Score=174, Evalue=4e-44,
Organism=Escherichia coli, GI1787558, Length=440, Percent_Identity=31.8181818181818, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1787684, Length=455, Percent_Identity=29.010989010989, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1786504, Length=446, Percent_Identity=29.1479820627803, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI1788042, Length=415, Percent_Identity=30.6024096385542, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1787715, Length=453, Percent_Identity=29.8013245033113, Blast_Score=150, Evalue=6e-37,
Organism=Escherichia coli, GI87082295, Length=438, Percent_Identity=28.9954337899543, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081926, Length=473, Percent_Identity=24.7357293868922, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534447, Length=445, Percent_Identity=32.3595505617978, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17562198, Length=445, Percent_Identity=31.685393258427, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25144435, Length=444, Percent_Identity=30.8558558558559, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=392, Percent_Identity=32.1428571428571, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI32564736, Length=404, Percent_Identity=31.9306930693069, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=451, Percent_Identity=28.8248337028825, Blast_Score=163, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=410, Percent_Identity=30.2439024390244, Blast_Score=152, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI25143876, Length=410, Percent_Identity=30.2439024390244, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=462, Percent_Identity=29.8701298701299, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=380, Percent_Identity=30.7894736842105, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=425, Percent_Identity=27.0588235294118, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71986308, Length=432, Percent_Identity=28.0092592592593, Blast_Score=130, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=447, Percent_Identity=26.3982102908277, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17551164, Length=456, Percent_Identity=25.219298245614, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=380, Percent_Identity=26.8421052631579, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=280, Percent_Identity=30, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=325, Percent_Identity=25.8461538461538, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25146391, Length=331, Percent_Identity=24.4712990936556, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32566756, Length=331, Percent_Identity=24.4712990936556, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=331, Percent_Identity=24.4712990936556, Blast_Score=86, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=444, Percent_Identity=34.009009009009, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324950, Length=441, Percent_Identity=31.0657596371882, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=461, Percent_Identity=30.58568329718, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=506, Percent_Identity=29.6442687747036, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=464, Percent_Identity=29.5258620689655, Blast_Score=157, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=455, Percent_Identity=28.5714285714286, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=420, Percent_Identity=25.7142857142857, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321828, Length=371, Percent_Identity=26.6846361185984, Blast_Score=101, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=442, Percent_Identity=22.8506787330317, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668425, Length=525, Percent_Identity=27.8095238095238, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24668417, Length=525, Percent_Identity=27.8095238095238, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24668413, Length=525, Percent_Identity=27.8095238095238, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24650465, Length=453, Percent_Identity=30.0220750551876, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI20129399, Length=445, Percent_Identity=29.6629213483146, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24585660, Length=558, Percent_Identity=26.5232974910394, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281362580, Length=449, Percent_Identity=28.9532293986637, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472918, Length=449, Percent_Identity=28.9532293986637, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472926, Length=449, Percent_Identity=28.9532293986637, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472936, Length=449, Percent_Identity=28.9532293986637, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21356737, Length=449, Percent_Identity=28.9532293986637, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571798, Length=400, Percent_Identity=27.25, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571796, Length=400, Percent_Identity=27.25, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571794, Length=400, Percent_Identity=27.25, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571806, Length=400, Percent_Identity=27.25, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571802, Length=400, Percent_Identity=27.25, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571800, Length=400, Percent_Identity=27.25, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24666674, Length=490, Percent_Identity=26.530612244898, Blast_Score=123, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28574525, Length=447, Percent_Identity=26.3982102908277, Blast_Score=120, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24638876, Length=431, Percent_Identity=26.6821345707657, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24638878, Length=431, Percent_Identity=26.6821345707657, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281360299, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281360297, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281360295, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586250, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281360301, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45552499, Length=334, Percent_Identity=25.4491017964072, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=25.4491017964072, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 121625; Mature: 121494

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDMRLRDRIDAGTYLDQANMRDALVALAALSEADRSAICASATQLVKDIRGHSSPGLM
CCCCCCHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EVFLAEYGLSTDEGVALMCLAEALLRVPDADTIDALIEDKIAPSDWGKHMGKSTSSLVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHH
STWALMLTGKVLDEEKSPVGALRGAIKRLGEPVIRTAVGRAMKEMGRQFVLGETIESAMK
HHEEEEEECHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
RASNMEAKGYTYSYDMLGEAARTEADASRYHLAYSRAISAIASACTSTDIRENPGISVKL
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SALHPRYEIAKEESVMQQLVPRLKALALLAKAAKMGLNIDAEEADRLSLSLEVIEEVISD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PALKGWDGFGVVVQAYGPRTGLAIDALYEMAEKYDRRFMVRLVKGAYWDTEIKRAQVEGM
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
DGFPVFTSKALTDVSYIANARKLLSRTDRIYPQFATHNAHTVSAILHMAEEGQAYEFQRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHH
HGMGETLHQMVMDQNKTRCRIYAPVGAHRDLLAYLVRRLLENGANSSFVNQIVDEDVPPQ
HHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
VVAADPFQEVDDLTTDIPTGPNLFQPERINSKGFDLRHAPTLAAIEKARAPFREATWDAV
EEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCC
PLIAGEAQPEARVAVTNPSDLSEIGSVSQSSAEDVELALASANTWDAPAEERAAALNKAA
EEEECCCCCCCEEEECCCCCHHHHHCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHH
DLYEAHYGELFALLAREAGKTQMDAVAELREAVDFLRYYASRIPDAAPAGIFTCISPWNF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
PLAIFTGQVSAALATGNAVLAKPADQTPLVAFRAVELLHEAGVPRDVLQFLPGRGSKVGA
CEEEEECCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCE
AITGDARINGVAFTGSTATAMRIRSAMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQ
EEECCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCHHHHH
AVVESAFQSAGQRCSALRCLYLQEDVAEDVLTMLKGAMELLDLDDPWHLATDSGPVIDEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
SRAKILAHIDEARAEGRVLKEMQAPQSGTFVAPTMISINGISDLKEEIFGPVLHVATFKS
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCEECCEEEEECCHHHHHHHHHHHHHHHHHCCC
RELDAVIDAINATGYGLTFGLQTRIDDRVQHVCDRIHAGNIYVNRNQIGAIVGSQPFGGE
CHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCC
GLSGTGPKAGGPNYLARFCAPDRRQVDAAWKDTMGEIPAARGQAGHPETTSLPGPTGESN
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
RLTVSARPPLLCAGPGAEAVSEQAKLVASLGGIAIEADGMVDLHRLAHMDGISGVLWWGD
EEEEECCCCEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCEEEEECC
ADTGREIEQSLAKREGPIVPLIPGAPDRARVLAERHVCVDTTAAGGNAALLGGNA
CCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCEEEEECCCCCCEEEECCCC
>Mature Secondary Structure 
TRDMRLRDRIDAGTYLDQANMRDALVALAALSEADRSAICASATQLVKDIRGHSSPGLM
CCCCCHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EVFLAEYGLSTDEGVALMCLAEALLRVPDADTIDALIEDKIAPSDWGKHMGKSTSSLVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHH
STWALMLTGKVLDEEKSPVGALRGAIKRLGEPVIRTAVGRAMKEMGRQFVLGETIESAMK
HHEEEEEECHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
RASNMEAKGYTYSYDMLGEAARTEADASRYHLAYSRAISAIASACTSTDIRENPGISVKL
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SALHPRYEIAKEESVMQQLVPRLKALALLAKAAKMGLNIDAEEADRLSLSLEVIEEVISD
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PALKGWDGFGVVVQAYGPRTGLAIDALYEMAEKYDRRFMVRLVKGAYWDTEIKRAQVEGM
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
DGFPVFTSKALTDVSYIANARKLLSRTDRIYPQFATHNAHTVSAILHMAEEGQAYEFQRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHH
HGMGETLHQMVMDQNKTRCRIYAPVGAHRDLLAYLVRRLLENGANSSFVNQIVDEDVPPQ
HHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
VVAADPFQEVDDLTTDIPTGPNLFQPERINSKGFDLRHAPTLAAIEKARAPFREATWDAV
EEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCC
PLIAGEAQPEARVAVTNPSDLSEIGSVSQSSAEDVELALASANTWDAPAEERAAALNKAA
EEEECCCCCCCEEEECCCCCHHHHHCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHH
DLYEAHYGELFALLAREAGKTQMDAVAELREAVDFLRYYASRIPDAAPAGIFTCISPWNF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCC
PLAIFTGQVSAALATGNAVLAKPADQTPLVAFRAVELLHEAGVPRDVLQFLPGRGSKVGA
CEEEEECCHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCE
AITGDARINGVAFTGSTATAMRIRSAMAEHCAPGTPLIAETGGLNAMIVDSTALPEQAVQ
EEECCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCHHHHH
AVVESAFQSAGQRCSALRCLYLQEDVAEDVLTMLKGAMELLDLDDPWHLATDSGPVIDEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCC
SRAKILAHIDEARAEGRVLKEMQAPQSGTFVAPTMISINGISDLKEEIFGPVLHVATFKS
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCEECCEEEEECCHHHHHHHHHHHHHHHHHCCC
RELDAVIDAINATGYGLTFGLQTRIDDRVQHVCDRIHAGNIYVNRNQIGAIVGSQPFGGE
CHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCC
GLSGTGPKAGGPNYLARFCAPDRRQVDAAWKDTMGEIPAARGQAGHPETTSLPGPTGESN
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
RLTVSARPPLLCAGPGAEAVSEQAKLVASLGGIAIEADGMVDLHRLAHMDGISGVLWWGD
EEEEECCCCEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCEEEEECC
ADTGREIEQSLAKREGPIVPLIPGAPDRARVLAERHVCVDTTAAGGNAALLGGNA
CCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCEEEEECCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]