Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 99081400

GI number: 99081400

Start: 1664004

End: 1665167

Strand: Direct

Name: mmgC [H]

Synonym: TM1040_1559

Alternate gene names: 99081400

Gene position: 1664004-1665167 (Clockwise)

Preceding gene: 99081399

Following gene: 99081401

Centisome position: 51.98

GC content: 59.11

Gene sequence:

>1164_bases
ATGAGCGCAGAGCTGGATTTTCGCACATCATCGGTGTGGATGACCGACGAGCATAAGATGCTCGCCGATATGACGCAGAG
CTTTATCACCAACGAATGGGCGCCCAAATTCGAGCGCTGGCGCAAACAGGGCGAGATGGATCGCTCGACATGGGCGCAGG
CCGGAGAACTGGGCCTGCTCTGCCCCTCCATCCCCGAGGAATACGGCGGTGCGGGCGGCGATTTTGGCCATGAGGCGGCG
ATCCTGATTGAGGCCAGCCGCGCCAATCTCGCCAGCTGGGGCCACGGGATCCACTCGGGCATCGTGGCGCATTACATCCT
CTCCTACGGTACCGAAGAGCAAAAACAGCGCTGGCTGCCCAAGATGGTGTCCGGCGAGTTGGTCGGCGCGCTGGCGATGA
CAGAGCCGTGTACCGGATCTGACGTGCAGGCGATCAAAACCAAGGCCATTCGTGATGGCAATGTTTATCGGCTCTCGGGC
CAGAAAACCTTTATTACCAATGGGCAACACGCCAACCTGATCCTTGTTGCGGCCAAGACCGACCCGTCCCAGGGCGCAAA
AGGCATCTCGCTTGTGGCGCTTGAAACCGAGGGCGCTGAAGGGTTCAGCCGGGGGCGTAACCTCGAGAAGGTCGGCCTGC
ACGCGGCGGATACCTCGGAGCTCTTTTTCGACAATATCGCTGTGCCACCGGAGAACATTCTGGGCGCAACGGAGGCGCAA
GGCTTTTACCAGATGATGCAGCAATTGCCGCAGGAACGGCTGATCATCGCCTGCGGCGCGGTTGGCGCGATGCAGGGCGC
GGTCGAGCGCACCATCGCATATTGTAAAGAGCGCGAAGCCTTTGGCGGGCCGCTCACGCAGTTCCAGAATACCCGTTTCA
AACTCGCCGAATGCCTGACCAAGAGTAAAGTCGCCCGCGCCTTCCTTGATGACTGCATGGTCCAGCACCTACGTGGAGAG
TTGACCGTCGAAAAGGCGGCGATGGCTAAATACTGGATCACCGACGCGCAAGGCGCTGTGCTTGATGAGTGCCTGCAATT
GCACGGAGGATATGGGTTCATGCAAGAATACGCCGTGGCAGAAATGTGGACCGATGCCCGTGTGCAGCGCATTTACGGCG
GCACCAATGAGATTATGAAAGAGCTGATTGCGAGGTCTCTATGA

Upstream 100 bases:

>100_bases
CGAGAACCTGACCCACCGGTTGCGGCTGTTCAATGCCGAATTGGAGGATCGAAAACGCTAGCGCAGGGCACGCACCGCCA
CGCGCCCAAGGGGGAGAGAG

Downstream 100 bases:

>100_bases
CAGTTCCAGCGCTTTCCCTTGCCGCGTCTGACGGATGCCTCCGGCGGGGATATTTCAGAGAAGTTGAAGGGATGGGGCGC
GCCTGCCCCCGAGCTCTCCG

Product: acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSAELDFRTSSVWMTDEHKMLADMTQSFITNEWAPKFERWRKQGEMDRSTWAQAGELGLLCPSIPEEYGGAGGDFGHEAA
ILIEASRANLASWGHGIHSGIVAHYILSYGTEEQKQRWLPKMVSGELVGALAMTEPCTGSDVQAIKTKAIRDGNVYRLSG
QKTFITNGQHANLILVAAKTDPSQGAKGISLVALETEGAEGFSRGRNLEKVGLHAADTSELFFDNIAVPPENILGATEAQ
GFYQMMQQLPQERLIIACGAVGAMQGAVERTIAYCKEREAFGGPLTQFQNTRFKLAECLTKSKVARAFLDDCMVQHLRGE
LTVEKAAMAKYWITDAQGAVLDECLQLHGGYGFMQEYAVAEMWTDARVQRIYGGTNEIMKELIARSL

Sequences:

>Translated_387_residues
MSAELDFRTSSVWMTDEHKMLADMTQSFITNEWAPKFERWRKQGEMDRSTWAQAGELGLLCPSIPEEYGGAGGDFGHEAA
ILIEASRANLASWGHGIHSGIVAHYILSYGTEEQKQRWLPKMVSGELVGALAMTEPCTGSDVQAIKTKAIRDGNVYRLSG
QKTFITNGQHANLILVAAKTDPSQGAKGISLVALETEGAEGFSRGRNLEKVGLHAADTSELFFDNIAVPPENILGATEAQ
GFYQMMQQLPQERLIIACGAVGAMQGAVERTIAYCKEREAFGGPLTQFQNTRFKLAECLTKSKVARAFLDDCMVQHLRGE
LTVEKAAMAKYWITDAQGAVLDECLQLHGGYGFMQEYAVAEMWTDARVQRIYGGTNEIMKELIARSL
>Mature_386_residues
SAELDFRTSSVWMTDEHKMLADMTQSFITNEWAPKFERWRKQGEMDRSTWAQAGELGLLCPSIPEEYGGAGGDFGHEAAI
LIEASRANLASWGHGIHSGIVAHYILSYGTEEQKQRWLPKMVSGELVGALAMTEPCTGSDVQAIKTKAIRDGNVYRLSGQ
KTFITNGQHANLILVAAKTDPSQGAKGISLVALETEGAEGFSRGRNLEKVGLHAADTSELFFDNIAVPPENILGATEAQG
FYQMMQQLPQERLIIACGAVGAMQGAVERTIAYCKEREAFGGPLTQFQNTRFKLAECLTKSKVARAFLDDCMVQHLRGEL
TVEKAAMAKYWITDAQGAVLDECLQLHGGYGFMQEYAVAEMWTDARVQRIYGGTNEIMKELIARSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=45.8885941644562, Blast_Score=329, Evalue=2e-90,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=34.0369393139842, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=35.2601156069364, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=31.6489361702128, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=34.1207349081365, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI7656849, Length=381, Percent_Identity=32.2834645669291, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=34.4729344729345, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=34.4729344729345, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=32.3759791122715, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=32.3759791122715, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=30.8093994778068, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=29.0488431876607, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=29.9168975069252, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI211971008, Length=294, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI48976061, Length=294, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.4429708222812, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=26.3852242744063, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=33.6870026525199, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=31.6353887399464, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=31.9034852546917, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=34.2541436464088, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=31.0077519379845, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=31.1855670103093, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=29.8666666666667, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=30.7106598984772, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=29.8666666666667, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=31.9371727748691, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=33.7883959044369, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=36.5638766519824, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=335, Percent_Identity=31.6417910447761, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=277, Percent_Identity=28.158844765343, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=26.5789473684211, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=294, Percent_Identity=29.9319727891156, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=25.9259259259259, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=33.5978835978836, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI21356377, Length=382, Percent_Identity=32.7225130890052, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24666513, Length=388, Percent_Identity=29.8969072164948, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=31.5926892950392, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=30.5699481865285, Blast_Score=167, Evalue=8e-42,
Organism=Drosophila melanogaster, GI281363737, Length=384, Percent_Identity=30.7291666666667, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=28.8311688311688, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42559; Mature: 42428

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELDFRTSSVWMTDEHKMLADMTQSFITNEWAPKFERWRKQGEMDRSTWAQAGELGLL
CCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCCCCC
CPSIPEEYGGAGGDFGHEAAILIEASRANLASWGHGIHSGIVAHYILSYGTEEQKQRWLP
CCCCCHHHCCCCCCCCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
KMVSGELVGALAMTEPCTGSDVQAIKTKAIRDGNVYRLSGQKTFITNGQHANLILVAAKT
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCEEEEECCCCCCEEEEEECC
DPSQGAKGISLVALETEGAEGFSRGRNLEKVGLHAADTSELFFDNIAVPPENILGATEAQ
CCCCCCCCEEEEEEECCCCHHHHHCCCCHHHCCCCCCCHHHHHCCCCCCHHHHCCCHHHH
GFYQMMQQLPQERLIIACGAVGAMQGAVERTIAYCKEREAFGGPLTQFQNTRFKLAECLT
HHHHHHHHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHH
KSKVARAFLDDCMVQHLRGELTVEKAAMAKYWITDAQGAVLDECLQLHGGYGFMQEYAVA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
EMWTDARVQRIYGGTNEIMKELIARSL
HHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAELDFRTSSVWMTDEHKMLADMTQSFITNEWAPKFERWRKQGEMDRSTWAQAGELGLL
CCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCCCCC
CPSIPEEYGGAGGDFGHEAAILIEASRANLASWGHGIHSGIVAHYILSYGTEEQKQRWLP
CCCCCHHHCCCCCCCCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
KMVSGELVGALAMTEPCTGSDVQAIKTKAIRDGNVYRLSGQKTFITNGQHANLILVAAKT
HHHCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCEEEEECCCCCCEEEEEECC
DPSQGAKGISLVALETEGAEGFSRGRNLEKVGLHAADTSELFFDNIAVPPENILGATEAQ
CCCCCCCCEEEEEEECCCCHHHHHCCCCHHHCCCCCCCHHHHHCCCCCCHHHHCCCHHHH
GFYQMMQQLPQERLIIACGAVGAMQGAVERTIAYCKEREAFGGPLTQFQNTRFKLAECLT
HHHHHHHHCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHH
KSKVARAFLDDCMVQHLRGELTVEKAAMAKYWITDAQGAVLDECLQLHGGYGFMQEYAVA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
EMWTDARVQRIYGGTNEIMKELIARSL
HHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]