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The map label for this gene is ccdA [H]

Identifier: 99081298

GI number: 99081298

Start: 1555970

End: 1556722

Strand: Reverse

Name: ccdA [H]

Synonym: TM1040_1457

Alternate gene names: 99081298

Gene position: 1556722-1555970 (Counterclockwise)

Preceding gene: 99081300

Following gene: 99081297

Centisome position: 48.63

GC content: 58.03

Gene sequence:

>753_bases
ATGTTTGGAATCGAGATCATAGACGCGAGCCTTCTGCCCGCCATGTTTGTTGCCCTTGTCGGGGGCATTATCAGCTTTCT
GAGCCCCTGCGTGCTGCCGATCGTTCCGCCCTATCTGGCGTATATGAGCGGCGTGACGATTGGCGAGATCCAAGGCACGG
CCGCTGCTCGGCGCAAGGCCATCCTGGCGGCGGTATTCTTTGTGATGGGGCTGTCGACGGTTTTCCTGCTCCTGGGGTTC
ACGGCCTCCGCGTTTGGCGCATTTGTTCTTCAAAATCAGGAGCTTTTTGCCAAAGCTTCAGGTGTCGTCGTGATCATTTT
TGGTCTGCATTTCCTGTCGGTTTTTCGGATTCCGATCCTGGATCGCGAAGCGCGGATGGAAACCGGCGAGACCGGCGGCT
CGGCACTTGGGGCCTATGTGCTTGGTCTGGCCTTTGCCTTTGGCTGGACGCCTTGCATCGGTCCGCAGCTTGGCGCGATC
CTGTCGCTTGCCGCCTCCGAGGCGTCCGTGAGCCGTGGTACGCTCCTGTTGGGGGTTTATGCACTGGGGTTGGGCGTGCC
GTTCCTTCTGGCAGCGATCTTCCTCAACAGATCCATGGTGCTGATGAACCGTATCAAACGCCACATGAGCCTCATTGAGA
AACTGATGGGCGGGTTGCTTCTGGTGGTGGGCTTCATGCTGGTCACAGGGCTTTTCACCAGCTTCTCTTTCTGGCTTCTC
GAAACCTTCCCGGCACTCGCAACTCTGGGCTAA

Upstream 100 bases:

>100_bases
AGTCATGCTTTCCGAGATAAGGCGCGTGTTACAGCCTGTCCACAAGGATGTGACACAGCGTGCAGGTGACGCCGTTGTGC
GCAGCGACTATGTACGGGTC

Downstream 100 bases:

>100_bases
GGACCAATCCCACCGCCACCCCGCCGCCCACGCGGGGTGCACGCACCATCTTACACTGCGCAGCAAGCTGAGTTAGGCTT
GGGCGCATAAAGATCGGGGC

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MFGIEIIDASLLPAMFVALVGGIISFLSPCVLPIVPPYLAYMSGVTIGEIQGTAAARRKAILAAVFFVMGLSTVFLLLGF
TASAFGAFVLQNQELFAKASGVVVIIFGLHFLSVFRIPILDREARMETGETGGSALGAYVLGLAFAFGWTPCIGPQLGAI
LSLAASEASVSRGTLLLGVYALGLGVPFLLAAIFLNRSMVLMNRIKRHMSLIEKLMGGLLLVVGFMLVTGLFTSFSFWLL
ETFPALATLG

Sequences:

>Translated_250_residues
MFGIEIIDASLLPAMFVALVGGIISFLSPCVLPIVPPYLAYMSGVTIGEIQGTAAARRKAILAAVFFVMGLSTVFLLLGF
TASAFGAFVLQNQELFAKASGVVVIIFGLHFLSVFRIPILDREARMETGETGGSALGAYVLGLAFAFGWTPCIGPQLGAI
LSLAASEASVSRGTLLLGVYALGLGVPFLLAAIFLNRSMVLMNRIKRHMSLIEKLMGGLLLVVGFMLVTGLFTSFSFWLL
ETFPALATLG
>Mature_250_residues
MFGIEIIDASLLPAMFVALVGGIISFLSPCVLPIVPPYLAYMSGVTIGEIQGTAAARRKAILAAVFFVMGLSTVFLLLGF
TASAFGAFVLQNQELFAKASGVVVIIFGLHFLSVFRIPILDREARMETGETGGSALGAYVLGLAFAFGWTPCIGPQLGAI
LSLAASEASVSRGTLLLGVYALGLGVPFLLAAIFLNRSMVLMNRIKRHMSLIEKLMGGLLLVVGFMLVTGLFTSFSFWLL
ETFPALATLG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=193, Percent_Identity=31.6062176165803, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26434; Mature: 26434

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCC
>Mature Secondary Structure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HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]