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The map label for this gene is gsiD [H]

Identifier: 99081260

GI number: 99081260

Start: 1513238

End: 1514674

Strand: Direct

Name: gsiD [H]

Synonym: TM1040_1419

Alternate gene names: 99081260

Gene position: 1513238-1514674 (Clockwise)

Preceding gene: 99081259

Following gene: 99081261

Centisome position: 47.27

GC content: 58.66

Gene sequence:

>1437_bases
ATGGACCCTTTGACTTGGACTGGCGCTCTTGGCTTTCTCACACCGATCCTGGTGATCGCGCTCATCCTGCTGGCGGCGAG
CATTGTGATCTGGATGTTGGCGTCCGCAATGAGCGCGGGCACACGCTATGTGGCAAATGCCGATGGCAGCCTCTCTCTTG
CAGGCAATCCGCAGGCGATGGCCGCGCTGGCGGTGCGCGCCACATTCGGCGCGGTCGCGGCGATCGCACTCGCCTATCTC
GTCCTGGGCCTGATCATGGGCACGGGTGCGGGGATCATCGGAGCAATTTCACAGCAGATGTGGCCCACCTGGGTCGCGCT
GCTCTTGCTGTTCTCGCTGTCGATCAAGTTCAAGAGACGCCTTGGGCTCTATGGCAAGCTCTTTGACAGCCCCATCGGCA
TGATCGGGTTTGGCCTCGTGATGTTCTGGGTCTTCACCGGCGTCTTTGGTGCGATGGACCTTATCGCCACCCATGACCCG
CTGGCGCAGGTCTCCGGCATGAAAAACAAAGTCCCCGGCACTCCGTTGCGCAGCGTGGAAGACGGAGAATATGCCTGGTA
TCTTCTCGGTGGAGACAACCTTGCACGGGACGTGTTCTCTCGCATGGTCAAAGGGGCGTGGGAGGTATTGAAGTACGCGC
CTCTGGCAACGCTTTTTGCCTTTATGGTTGGGATCACATTGGGGCTTCCGGCAGGCTATTACGGTGGCAAGCTCGATACG
TTCCTGTCCTTCCTTGCCAACCTCATTCTGGCCTTTCCGGTGATCCTGCTGTTCTACCTTCTGGTGACGCCCGAGATCGT
TGCGACAGGCCTGCCGCAGTATATGGCGGTGGTGCTCTTTGCCTTTCCAATGGTGTTTTGCGGGGTCTTGATCCACTCAA
GATTTCGCACACAGCCCAGCAAGAACGCTTTCTGGCTGGCGTTGGTTCTGGTTCCGATGGTCCTGATGTACATGTCGCTC
ATCAACGCCGAAGGTTCCAAAATCGCGTTTTGGCCGCTGGATTTCTTTGACATTCCCGGGGGGGTGCTGGTGGTGTTTGT
CTCGGTGGTGTTTGTGAACTCCCCCACGGTGTTTCGGATCGTGCGTGGCCTTGCGCTGGACATCAAGACCCGCGACTACG
TCGCTGCCGCGCAGACCCGTGGTGAGCGCCCCTGGTACATCATGCTGTGGGAGATCCTGCCCAATGTCCGCGGTCCATTG
ATCGTCGATTTCTGCCTGCGCATTGGGTACACCACCATCCTACTGGGAACACTTGGATTTTTTGGCCTTGGCCTGCCGCC
GGAAAGCCCCGATTGGGGCTCCACCATCAATGATGGACGCAAGCTGTTGTCGATCTATCTGCACCCCGCCCTGCCGCCCG
CCATTGCCCTGATGAGCCTTGTTCTTGGGCTCAACCTGCTGGCAGATGGATTGCGTGAAGAGAGCCTTCGGGACTGA

Upstream 100 bases:

>100_bases
CGTCTCCGTCATCGTGGTTCTGTTGACGCAGCTGATTTCCGACATCGGCTACATCTTCTTGAACCCCCGTATCCGTATCT
CGTAAGGCAGGAGGCTTTTC

Downstream 100 bases:

>100_bases
TGAGAACACGGCCGGGGGCGCTGCCCCCGGACCCCCGGGATATTTTGGGTTAGAAGAGGCTTTGAGGTCTCGGCTGACCC
GTCAGGGAGAGCAAAATGAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MDPLTWTGALGFLTPILVIALILLAASIVIWMLASAMSAGTRYVANADGSLSLAGNPQAMAALAVRATFGAVAAIALAYL
VLGLIMGTGAGIIGAISQQMWPTWVALLLLFSLSIKFKRRLGLYGKLFDSPIGMIGFGLVMFWVFTGVFGAMDLIATHDP
LAQVSGMKNKVPGTPLRSVEDGEYAWYLLGGDNLARDVFSRMVKGAWEVLKYAPLATLFAFMVGITLGLPAGYYGGKLDT
FLSFLANLILAFPVILLFYLLVTPEIVATGLPQYMAVVLFAFPMVFCGVLIHSRFRTQPSKNAFWLALVLVPMVLMYMSL
INAEGSKIAFWPLDFFDIPGGVLVVFVSVVFVNSPTVFRIVRGLALDIKTRDYVAAAQTRGERPWYIMLWEILPNVRGPL
IVDFCLRIGYTTILLGTLGFFGLGLPPESPDWGSTINDGRKLLSIYLHPALPPAIALMSLVLGLNLLADGLREESLRD

Sequences:

>Translated_478_residues
MDPLTWTGALGFLTPILVIALILLAASIVIWMLASAMSAGTRYVANADGSLSLAGNPQAMAALAVRATFGAVAAIALAYL
VLGLIMGTGAGIIGAISQQMWPTWVALLLLFSLSIKFKRRLGLYGKLFDSPIGMIGFGLVMFWVFTGVFGAMDLIATHDP
LAQVSGMKNKVPGTPLRSVEDGEYAWYLLGGDNLARDVFSRMVKGAWEVLKYAPLATLFAFMVGITLGLPAGYYGGKLDT
FLSFLANLILAFPVILLFYLLVTPEIVATGLPQYMAVVLFAFPMVFCGVLIHSRFRTQPSKNAFWLALVLVPMVLMYMSL
INAEGSKIAFWPLDFFDIPGGVLVVFVSVVFVNSPTVFRIVRGLALDIKTRDYVAAAQTRGERPWYIMLWEILPNVRGPL
IVDFCLRIGYTTILLGTLGFFGLGLPPESPDWGSTINDGRKLLSIYLHPALPPAIALMSLVLGLNLLADGLREESLRD
>Mature_478_residues
MDPLTWTGALGFLTPILVIALILLAASIVIWMLASAMSAGTRYVANADGSLSLAGNPQAMAALAVRATFGAVAAIALAYL
VLGLIMGTGAGIIGAISQQMWPTWVALLLLFSLSIKFKRRLGLYGKLFDSPIGMIGFGLVMFWVFTGVFGAMDLIATHDP
LAQVSGMKNKVPGTPLRSVEDGEYAWYLLGGDNLARDVFSRMVKGAWEVLKYAPLATLFAFMVGITLGLPAGYYGGKLDT
FLSFLANLILAFPVILLFYLLVTPEIVATGLPQYMAVVLFAFPMVFCGVLIHSRFRTQPSKNAFWLALVLVPMVLMYMSL
INAEGSKIAFWPLDFFDIPGGVLVVFVSVVFVNSPTVFRIVRGLALDIKTRDYVAAAQTRGERPWYIMLWEILPNVRGPL
IVDFCLRIGYTTILLGTLGFFGLGLPPESPDWGSTINDGRKLLSIYLHPALPPAIALMSLVLGLNLLADGLREESLRD

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=134, Percent_Identity=35.8208955223881, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787760, Length=129, Percent_Identity=37.984496124031, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787549, Length=287, Percent_Identity=25.7839721254355, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789964, Length=127, Percent_Identity=32.2834645669291, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 51860; Mature: 51860

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00761 SPASE_I_3 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLTWTGALGFLTPILVIALILLAASIVIWMLASAMSAGTRYVANADGSLSLAGNPQAM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHH
AALAVRATFGAVAAIALAYLVLGLIMGTGAGIIGAISQQMWPTWVALLLLFSLSIKFKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGKLFDSPIGMIGFGLVMFWVFTGVFGAMDLIATHDPLAQVSGMKNKVPGTPLRSVE
HCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC
DGEYAWYLLGGDNLARDVFSRMVKGAWEVLKYAPLATLFAFMVGITLGLPAGYYGGKLDT
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
FLSFLANLILAFPVILLFYLLVTPEIVATGLPQYMAVVLFAFPMVFCGVLIHSRFRTQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNAFWLALVLVPMVLMYMSLINAEGSKIAFWPLDFFDIPGGVLVVFVSVVFVNSPTVFRI
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHHHCCCCHHHHH
VRGLALDIKTRDYVAAAQTRGERPWYIMLWEILPNVRGPLIVDFCLRIGYTTILLGTLGF
HHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGLGLPPESPDWGSTINDGRKLLSIYLHPALPPAIALMSLVLGLNLLADGLREESLRD
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPLTWTGALGFLTPILVIALILLAASIVIWMLASAMSAGTRYVANADGSLSLAGNPQAM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHH
AALAVRATFGAVAAIALAYLVLGLIMGTGAGIIGAISQQMWPTWVALLLLFSLSIKFKRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLYGKLFDSPIGMIGFGLVMFWVFTGVFGAMDLIATHDPLAQVSGMKNKVPGTPLRSVE
HCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC
DGEYAWYLLGGDNLARDVFSRMVKGAWEVLKYAPLATLFAFMVGITLGLPAGYYGGKLDT
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
FLSFLANLILAFPVILLFYLLVTPEIVATGLPQYMAVVLFAFPMVFCGVLIHSRFRTQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KNAFWLALVLVPMVLMYMSLINAEGSKIAFWPLDFFDIPGGVLVVFVSVVFVNSPTVFRI
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHHHCCCCHHHHH
VRGLALDIKTRDYVAAAQTRGERPWYIMLWEILPNVRGPLIVDFCLRIGYTTILLGTLGF
HHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FGLGLPPESPDWGSTINDGRKLLSIYLHPALPPAIALMSLVLGLNLLADGLREESLRD
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA