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The map label for this gene is appB [H]

Identifier: 99081259

GI number: 99081259

Start: 1512170

End: 1513222

Strand: Direct

Name: appB [H]

Synonym: TM1040_1418

Alternate gene names: 99081259

Gene position: 1512170-1513222 (Clockwise)

Preceding gene: 99081258

Following gene: 99081260

Centisome position: 47.24

GC content: 56.98

Gene sequence:

>1053_bases
ATGGGACCATTCATATTGCGCCGCACGGGTGTGATGATCATTACGGCTTTGTGCCTGACGTTCATCGTCTTCGTGATGAC
CAATCTCTATCCAAACCTCGAAAAACTCGCCAAGACCGAAGGCAACTTCCGCATGTCGGACGAAGCGGTTGCAAGCTGGC
TTGATAAGAATGGCTACGGTCAGCCGATGCTGTTGAAATACGGCCAGTGGCTGGGCGTGGTTCCCGGTTGGCAGCGCAGC
GGCGAGGAAGGCGTCACCGGGCGTTGCATTGATGGAACCGTCACCCCGGAAGAAGCCGCGCAGGCCGCGCGGTTTTGTGG
CATTCTGCAAGGCGACTGGGGCTATTCCACACGTTTCAAAACAGACGTGAGCGAAATCATCCAGACCCGGCTGGGCAACA
CCGGCTATCTGATGATGTGGGTTTTGATCCTCATGGTGCCCTCGGCCCTGATCGTGGGCGTTCTGGCCGGGATGCGCGAA
GGTTCGGCAACCGACAGGTCCCTGTCGACCGTGTCGATCATGACGACCGCGACGCCGGAATATGTGTCGGGCGTGATCTT
CATTGCGGTCTTTGCCTCCTCCACAGTGGGGCTCAAATGGTTCAAAGGCACCGCAACCGCTGCCATGGAGAACCCGACGT
TTGAGAATTTCTTCCTGCCGGTACTGACCATCGCGCTCTATGGCATGGGCTATATCGCCCGGATGACACGCGCCTCCATG
ACCGAAGTGATGACGGCCCAATACATCCGGACTGCACGCCTTAAGGGGGTGAGTTTTCCAAACATCGTTCTGCGCCACGC
GCTGCGCAATGCGTTGATTGCCCCCTTCACGGTAATCATGCTGCAGTTCCCCTGGTTGTTGAACGGAGTCGTGATTGTCG
AAACCTTGTTTAACTACAAGGGCTTCGGCTGGGCACTGGTCGAGGCGGCCAGCAACAACGACATCGAGCTTCTGCTGGCG
ATTTCGGTCGTCTCCGTCATCGTGGTTCTGTTGACGCAGCTGATTTCCGACATCGGCTACATCTTCTTGAACCCCCGTAT
CCGTATCTCGTAA

Upstream 100 bases:

>100_bases
GCACCACGCCTGAATTCAAAACAATAAAGGCCTCCGCGATTTGGACGACCCACGTCCAAATGTCTCAGGGCCAGCTGACC
GCCAGTCTGCAGGGGAACAC

Downstream 100 bases:

>100_bases
GGCAGGAGGCTTTTCATGGACCCTTTGACTTGGACTGGCGCTCTTGGCTTTCTCACACCGATCCTGGTGATCGCGCTCAT
CCTGCTGGCGGCGAGCATTG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MGPFILRRTGVMIITALCLTFIVFVMTNLYPNLEKLAKTEGNFRMSDEAVASWLDKNGYGQPMLLKYGQWLGVVPGWQRS
GEEGVTGRCIDGTVTPEEAAQAARFCGILQGDWGYSTRFKTDVSEIIQTRLGNTGYLMMWVLILMVPSALIVGVLAGMRE
GSATDRSLSTVSIMTTATPEYVSGVIFIAVFASSTVGLKWFKGTATAAMENPTFENFFLPVLTIALYGMGYIARMTRASM
TEVMTAQYIRTARLKGVSFPNIVLRHALRNALIAPFTVIMLQFPWLLNGVVIVETLFNYKGFGWALVEAASNNDIELLLA
ISVVSVIVVLLTQLISDIGYIFLNPRIRIS

Sequences:

>Translated_350_residues
MGPFILRRTGVMIITALCLTFIVFVMTNLYPNLEKLAKTEGNFRMSDEAVASWLDKNGYGQPMLLKYGQWLGVVPGWQRS
GEEGVTGRCIDGTVTPEEAAQAARFCGILQGDWGYSTRFKTDVSEIIQTRLGNTGYLMMWVLILMVPSALIVGVLAGMRE
GSATDRSLSTVSIMTTATPEYVSGVIFIAVFASSTVGLKWFKGTATAAMENPTFENFFLPVLTIALYGMGYIARMTRASM
TEVMTAQYIRTARLKGVSFPNIVLRHALRNALIAPFTVIMLQFPWLLNGVVIVETLFNYKGFGWALVEAASNNDIELLLA
ISVVSVIVVLLTQLISDIGYIFLNPRIRIS
>Mature_349_residues
GPFILRRTGVMIITALCLTFIVFVMTNLYPNLEKLAKTEGNFRMSDEAVASWLDKNGYGQPMLLKYGQWLGVVPGWQRSG
EEGVTGRCIDGTVTPEEAAQAARFCGILQGDWGYSTRFKTDVSEIIQTRLGNTGYLMMWVLILMVPSALIVGVLAGMREG
SATDRSLSTVSIMTTATPEYVSGVIFIAVFASSTVGLKWFKGTATAAMENPTFENFFLPVLTIALYGMGYIARMTRASMT
EVMTAQYIRTARLKGVSFPNIVLRHALRNALIAPFTVIMLQFPWLLNGVVIVETLFNYKGFGWALVEAASNNDIELLLAI
SVVSVIVVLLTQLISDIGYIFLNPRIRIS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=240, Percent_Identity=32.0833333333333, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789965, Length=368, Percent_Identity=27.7173913043478, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787497, Length=346, Percent_Identity=25.4335260115607, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789888, Length=348, Percent_Identity=25, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788504, Length=390, Percent_Identity=24.3589743589744, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787761, Length=359, Percent_Identity=24.5125348189415, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787550, Length=287, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38550; Mature: 38419

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPFILRRTGVMIITALCLTFIVFVMTNLYPNLEKLAKTEGNFRMSDEAVASWLDKNGYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECHHHHHHHHHCCCCC
QPMLLKYGQWLGVVPGWQRSGEEGVTGRCIDGTVTPEEAAQAARFCGILQGDWGYSTRFK
CCHHHHHCCHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCH
TDVSEIIQTRLGNTGYLMMWVLILMVPSALIVGVLAGMREGSATDRSLSTVSIMTTATPE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHH
YVSGVIFIAVFASSTVGLKWFKGTATAAMENPTFENFFLPVLTIALYGMGYIARMTRASM
HHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVMTAQYIRTARLKGVSFPNIVLRHALRNALIAPFTVIMLQFPWLLNGVVIVETLFNYK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GFGWALVEAASNNDIELLLAISVVSVIVVLLTQLISDIGYIFLNPRIRIS
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEC
>Mature Secondary Structure 
GPFILRRTGVMIITALCLTFIVFVMTNLYPNLEKLAKTEGNFRMSDEAVASWLDKNGYG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEECHHHHHHHHHCCCCC
QPMLLKYGQWLGVVPGWQRSGEEGVTGRCIDGTVTPEEAAQAARFCGILQGDWGYSTRFK
CCHHHHHCCHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCH
TDVSEIIQTRLGNTGYLMMWVLILMVPSALIVGVLAGMREGSATDRSLSTVSIMTTATPE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHH
YVSGVIFIAVFASSTVGLKWFKGTATAAMENPTFENFFLPVLTIALYGMGYIARMTRASM
HHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVMTAQYIRTARLKGVSFPNIVLRHALRNALIAPFTVIMLQFPWLLNGVVIVETLFNYK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
GFGWALVEAASNNDIELLLAISVVSVIVVLLTQLISDIGYIFLNPRIRIS
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]