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The map label for this gene is mhpC [C]

Identifier: 99081221

GI number: 99081221

Start: 1474186

End: 1475151

Strand: Direct

Name: mhpC [C]

Synonym: TM1040_1380

Alternate gene names: 99081221

Gene position: 1474186-1475151 (Clockwise)

Preceding gene: 99081220

Following gene: 99081222

Centisome position: 46.05

GC content: 62.73

Gene sequence:

>966_bases
ATGAGTGCCATCCTTGCTCTTGCCGTGACGCTTGGCTTTGCTGGGGTTGCGGGCTTTACCGCCCTGCGCGCCCCACTGCG
CGAGGCCGAGAGTATCGCCAATCATCCGCCTCAAGGACAGTTCCTGAACGTGGACGGCCATCAGATCCATGTGGTCGAGC
GCGGCCAGCCGCAAGGCAGCGCCCCTGATCTGGTGCTGATTCATGGGTCCAACGGCAGCATCCGGGACATGACGTTCCGA
CTGTCGCCCGCGCTCGAAGAGGCCTATCGCATCTTGATCTTTGATCGACCTGGGCTTGGCTATTCCGATGCAATCTCCGC
TGATGGGACCAGCATCCAAACCCAGGCGGCCATTTTGCAAAAAGCCAGCGCGCGCCTCGGCGCACAGCGCCCGATCGTGC
TGGGCCAAAGCTACGGGGGCGCCGTGGCGCTCGCCTGGGCGACGGAGTTTCCGCAGCATACCGCAGCCGTTGTCAGCGTT
TCTGGTGTATCGCACCCTTGGGACGCGGAACTACCGACCTTTTACAAACTGACCTCGTCGCGCTTTGGCAGCGCGGTCAT
CGTCCCGCTGCTCACCGCCTTTGTGCCCAAGAGCTATGTACGCGACTCGCTCAAGGACGTCTTTGCCCCGCAGGCGGTGC
CCGACGGGTTTGCAGATCATTTTGGGCTCGCCATGAGCCTGCGCCGCAGTTCCTTGCGGGCCAATGCCAAGCAGCGCGCC
AATCTTCTGACCGAGGTCGAGGCGATGGCGCCAAAGTATCCTGACCTCAGCATGCCCATCGAAGTGGTGCACGGCACCGC
CGACACCACCGTGGGCATATCAATTCATGCCGAGCGCCTTGTTGCGGACAGCCGGACCGCGCGTCTCACGCCGTTGCCGG
ATGTTGGACATATGCCGCATCAGACCCACACGCAGGAGGTGGTGGCAGCGGTCCATCGAGCGGCAACGCGGGCAAACTTG
CGTTAA

Upstream 100 bases:

>100_bases
GCTCTATGGCAACTGGGTGTCTGAAATCTATCAGACGACCCCATATGATGTGGAGCGCATCGGTCTCGACACGACGGACC
TTCGGGCCTGATCTTTGCGG

Downstream 100 bases:

>100_bases
TCGCTTTAACATTGAACAGTGACAGGGCAAGTGTGGGCGGGCGAGAAAGGACAGGGTGGAAATGACTTTGCCATTTGACG
GCGCAATCAGCCAGTATTTC

Product: alpha/beta hydrolase fold

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: Alpha/Beta Hydrolase; Alpha/Beta Hydrolase Fold Protein; Esterase; Alpha/Beta Hydrolase Fold-Containing Protein; Lactone-Specific Esterase; Alpha/Beta Fold Family Hydrolase; Hydrolase Alpha/Beta Fold Family; Hydrolase Or Acyltransferase; Hydrolase Alpha/Beta Fold Family Protein; Esterase/Hydrolase; Lactone-Specific Esterase Protein; Family; Alpha/Beta Fold Superfamily Hydrolase; Esterase/Hydrolase Protein; Esterase Protein; 2-Hydroxy-6-Oxo-6-Phenylhexa-2 4-Dienoate Hydrolase; Hydrolase; Lactone Esterase

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSAILALAVTLGFAGVAGFTALRAPLREAESIANHPPQGQFLNVDGHQIHVVERGQPQGSAPDLVLIHGSNGSIRDMTFR
LSPALEEAYRILIFDRPGLGYSDAISADGTSIQTQAAILQKASARLGAQRPIVLGQSYGGAVALAWATEFPQHTAAVVSV
SGVSHPWDAELPTFYKLTSSRFGSAVIVPLLTAFVPKSYVRDSLKDVFAPQAVPDGFADHFGLAMSLRRSSLRANAKQRA
NLLTEVEAMAPKYPDLSMPIEVVHGTADTTVGISIHAERLVADSRTARLTPLPDVGHMPHQTHTQEVVAAVHRAATRANL
R

Sequences:

>Translated_321_residues
MSAILALAVTLGFAGVAGFTALRAPLREAESIANHPPQGQFLNVDGHQIHVVERGQPQGSAPDLVLIHGSNGSIRDMTFR
LSPALEEAYRILIFDRPGLGYSDAISADGTSIQTQAAILQKASARLGAQRPIVLGQSYGGAVALAWATEFPQHTAAVVSV
SGVSHPWDAELPTFYKLTSSRFGSAVIVPLLTAFVPKSYVRDSLKDVFAPQAVPDGFADHFGLAMSLRRSSLRANAKQRA
NLLTEVEAMAPKYPDLSMPIEVVHGTADTTVGISIHAERLVADSRTARLTPLPDVGHMPHQTHTQEVVAAVHRAATRANL
R
>Mature_320_residues
SAILALAVTLGFAGVAGFTALRAPLREAESIANHPPQGQFLNVDGHQIHVVERGQPQGSAPDLVLIHGSNGSIRDMTFRL
SPALEEAYRILIFDRPGLGYSDAISADGTSIQTQAAILQKASARLGAQRPIVLGQSYGGAVALAWATEFPQHTAAVVSVS
GVSHPWDAELPTFYKLTSSRFGSAVIVPLLTAFVPKSYVRDSLKDVFAPQAVPDGFADHFGLAMSLRRSSLRANAKQRAN
LLTEVEAMAPKYPDLSMPIEVVHGTADTTVGISIHAERLVADSRTARLTPLPDVGHMPHQTHTQEVVAAVHRAATRANLR

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.7.1.- [C]

Molecular weight: Translated: 34238; Mature: 34107

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAILALAVTLGFAGVAGFTALRAPLREAESIANHPPQGQFLNVDGHQIHVVERGQPQGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCC
APDLVLIHGSNGSIRDMTFRLSPALEEAYRILIFDRPGLGYSDAISADGTSIQTQAAILQ
CCCEEEEECCCCCEEEEEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
KASARLGAQRPIVLGQSYGGAVALAWATEFPQHTAAVVSVSGVSHPWDAELPTFYKLTSS
HHHHHCCCCCCEEEECCCCCEEEEEEEHHCCCHHEEEEEECCCCCCCCCCCCHHHHHHHH
RFGSAVIVPLLTAFVPKSYVRDSLKDVFAPQAVPDGFADHFGLAMSLRRSSLRANAKQRA
CCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
NLLTEVEAMAPKYPDLSMPIEVVHGTADTTVGISIHAERLVADSRTARLTPLPDVGHMPH
HHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCC
QTHTQEVVAAVHRAATRANLR
CCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAILALAVTLGFAGVAGFTALRAPLREAESIANHPPQGQFLNVDGHQIHVVERGQPQGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCCCCC
APDLVLIHGSNGSIRDMTFRLSPALEEAYRILIFDRPGLGYSDAISADGTSIQTQAAILQ
CCCEEEEECCCCCEEEEEEEECHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
KASARLGAQRPIVLGQSYGGAVALAWATEFPQHTAAVVSVSGVSHPWDAELPTFYKLTSS
HHHHHCCCCCCEEEECCCCCEEEEEEEHHCCCHHEEEEEECCCCCCCCCCCCHHHHHHHH
RFGSAVIVPLLTAFVPKSYVRDSLKDVFAPQAVPDGFADHFGLAMSLRRSSLRANAKQRA
CCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHH
NLLTEVEAMAPKYPDLSMPIEVVHGTADTTVGISIHAERLVADSRTARLTPLPDVGHMPH
HHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCC
QTHTQEVVAAVHRAATRANLR
CCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA