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The map label for this gene is quiP [H]

Identifier: 99081195

GI number: 99081195

Start: 1444280

End: 1446769

Strand: Direct

Name: quiP [H]

Synonym: TM1040_1354

Alternate gene names: 99081195

Gene position: 1444280-1446769 (Clockwise)

Preceding gene: 99081193

Following gene: 99081205

Centisome position: 45.12

GC content: 61.65

Gene sequence:

>2490_bases
ATGGCACGCCTCTTCCGCTGGCTCCTCCGCCTCACGGCTGGTACGATTCTGCTTGGTATTCTGGGGGCGATCCTGGTCTA
TTTCCTCGCGGCGCAGTCCTTGCCAGACTATGACAAGGAGATCGCCCTGCCCGGCCCTACGGCTCCGGTCGAGATCGTGC
GCGACAACGCGAATGTGCCGCATATCTTTGGCAGCTTTGGTGCCTCGGATGAGGACGTGTTTTTTGGGCTCGGGTATGCT
CATGCGCAGGATCGACTGTGGCAGATGGCCGTGATGCGACGCACGGCGCAGGGTCGGCTTTCCGAGGTCTTTGGCCCCCG
TACCGTCCGCACAGACAGTTTTTTGCGGCGGCTTGATCTTTATGGGGCGGCGCGAAGTTCGGTTTCCGCCCAGAGCCCCG
AAACGCTCCGGGCGCTGCAGGCCTATGCTGCGGGCGTGAATGCGCGCCTGCAAGAGATCAACGAAGACGCGCTGGGGCGT
GGGGCACCGGAAATGTTCCTGTTCAACATGCCCATAGCGCCGTGGCAGCCCGCCGACAGCATCGCCATTATGAAACTGAT
GGCCGTGCAGCTCTCATCCAATATGCAAGAAGAGATCCTGCGCGCGCAGACTTCCATTGCCCTCGATGATCCCAAACGCC
TTGAGGATATCCTGCCCGATGCTCCCGGCTCTGGGACGGCGACGCTTCCGGAATATACGGAGCTGTTTCCCGGCCTCCCG
GGATTTCGTGGTCTCGAGGAACAGCGCCGGGCGCAAACGGCGCATGCTGCGTTGATGCCCCTGGCGCCACGTGGGCTTGG
TGGGGCTTCGAATGCCTGGGCTGCGGCGCCCAATCGTTCGGCGGCGGGTGGCACGCTTCTTGCCAATGACCCGCATCTGA
AGCTGACAGCGCCCGGAACCTGGTATCTGGCACGTCTTGAGCTTGGCACCGGCGGTGTGATTGGTGGCACAATCCCGGGC
ATCCCGGCTGTGCTCACCGGGCGTTCTCAGCAGTTGGGATGGGGGCTCACCTCTTCCTATCTGGATGATCAGGACCTCTT
TATCGAGAAGATCAACCCGGACAACCCGCAGCAGTATCTGACCCCAAATGGCTACAAGGACTTCACATCGCGGCCTTCGA
TCGTGCAGATAAAGGGCAATGCGCCGCTGACGCTGACCCTGCGCTGGACCGAAAACGGGCCGGTTCTGCCCGGCTCGCTG
TTTGAGCTCAGCACCATTACGCCGCCCGGCCACGTTGTGAGCCTAGGGTGGACGGCATTGTCGCGCGAGGACACCTCGAT
GACTGCGGCGCTCGATCTGATGCGGGCAGAAAATGTCGCGCAGGCCATTGCCGCAGGCGAGAACTTCATCGCGCCTTCCC
AAAATATCACGCTGGCGGATCATGACACCATCGCGCTCAAGACCGTGGGCGTCATGCCCGACCGCGACCTGCGCAACCAA
AGCCGGGGACGCCTGCCCAACCAGGGCTGGCGGCGCGAAAACCGCTGGCAAGGGCGCTTGCCCTATGCGGCGAACCCGGA
GTTCATTGCGCCCAGCGGTGGGATTTTGGGAAATACAAACAACAAGTTGCTAGAGCGCCCCTTTCCCAACCACGTCAGTT
ATTCCTGGGGCGACACACAGCGGATCAATCGCTGGCGCCGTCTGATGCAGAGCCGCGAGGTGCATACCCGCGACAGTTTC
ATCGAAGCGCAGCTCGATACGGTTTCCTATAGCGCGCAAACCCTCCTGCCTCTTATCGGGGCGGATCTGTGGTTCACCGG
TGAAGCTGCGCCCAATGGCACGCCGGAACGCCAGCGCCAGATCGCATTGTCGCTCTTGGCGGAGTGGAACGGCGAGATGA
ACGAGCATTTGCCCGAGCCTCTGATCTACGCAAGTTGGGTGCGTGCTTTGCAAAAACGTCTGATCGAGGACGACCTAGGC
CCCCTTGCGGATGCGTTTGACCGGGTTGAGCCGCTGTTCCTGGAACGGGTGTTCCGCAATATCGATGGCGCTGCAGCCTG
GTGTGATGTCGCCCAGAGCGCCCCGACCGAGAGCTGCACCGACATGGCGCGCCTCGCGCTGGACGACGCGCTCGTCTACA
TCAGCGAAAACTACGGCAGTACATTGGAAAGCCTGCGCTGGGGGGATGCGCATCAGGCCACCCAGGATCACGAGGTCTTG
GGCGAGGTGCCGTTCCTGCGCTATTTCGTCAACATCCGTCAATCCACCAGTGGTGGAGACAATACGCTGCAGCGCGGCCT
CACCTCGGGCGAGGAGCCGGCGCCCTTCAACAATGTGCATGGGGCGGGCTATCGCGGTGTCTATGATTTCGCCGATCCCG
AAAGCTCTGTTTTCATTATAGCAACAGGCCAGTCCGGGCATTTCCTGTCGCGCTACTACGATGACATGGCACAGTACTGG
CGGCGTGGGGAGTATATCCCGATGTCTCTCGACGAAAAACTGGCGCGCGCCGCTTCCGTCGGCGTCACCCGTATCCTGCC
GCGCAACTAA

Upstream 100 bases:

>100_bases
GTTCTGTCTTCGCATATGTTGGCGCCAACCCTAGCAGCACCCGCCCAAAGCGCAATGCGGCTTGGCAACAAACACAGAAA
TACCAAGGGAATAGAAAAGA

Downstream 100 bases:

>100_bases
AGAAAAACGCAGCGCTCTAGAGCGCTGCGTATTGTGCTTTTTGCTTTTCGGTCCAGCGCACGGAAATCTCAAACCCGGTG
TCGGTCTGGTTTTCCTCTTG

Product: penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MARLFRWLLRLTAGTILLGILGAILVYFLAAQSLPDYDKEIALPGPTAPVEIVRDNANVPHIFGSFGASDEDVFFGLGYA
HAQDRLWQMAVMRRTAQGRLSEVFGPRTVRTDSFLRRLDLYGAARSSVSAQSPETLRALQAYAAGVNARLQEINEDALGR
GAPEMFLFNMPIAPWQPADSIAIMKLMAVQLSSNMQEEILRAQTSIALDDPKRLEDILPDAPGSGTATLPEYTELFPGLP
GFRGLEEQRRAQTAHAALMPLAPRGLGGASNAWAAAPNRSAAGGTLLANDPHLKLTAPGTWYLARLELGTGGVIGGTIPG
IPAVLTGRSQQLGWGLTSSYLDDQDLFIEKINPDNPQQYLTPNGYKDFTSRPSIVQIKGNAPLTLTLRWTENGPVLPGSL
FELSTITPPGHVVSLGWTALSREDTSMTAALDLMRAENVAQAIAAGENFIAPSQNITLADHDTIALKTVGVMPDRDLRNQ
SRGRLPNQGWRRENRWQGRLPYAANPEFIAPSGGILGNTNNKLLERPFPNHVSYSWGDTQRINRWRRLMQSREVHTRDSF
IEAQLDTVSYSAQTLLPLIGADLWFTGEAAPNGTPERQRQIALSLLAEWNGEMNEHLPEPLIYASWVRALQKRLIEDDLG
PLADAFDRVEPLFLERVFRNIDGAAAWCDVAQSAPTESCTDMARLALDDALVYISENYGSTLESLRWGDAHQATQDHEVL
GEVPFLRYFVNIRQSTSGGDNTLQRGLTSGEEPAPFNNVHGAGYRGVYDFADPESSVFIIATGQSGHFLSRYYDDMAQYW
RRGEYIPMSLDEKLARAASVGVTRILPRN

Sequences:

>Translated_829_residues
MARLFRWLLRLTAGTILLGILGAILVYFLAAQSLPDYDKEIALPGPTAPVEIVRDNANVPHIFGSFGASDEDVFFGLGYA
HAQDRLWQMAVMRRTAQGRLSEVFGPRTVRTDSFLRRLDLYGAARSSVSAQSPETLRALQAYAAGVNARLQEINEDALGR
GAPEMFLFNMPIAPWQPADSIAIMKLMAVQLSSNMQEEILRAQTSIALDDPKRLEDILPDAPGSGTATLPEYTELFPGLP
GFRGLEEQRRAQTAHAALMPLAPRGLGGASNAWAAAPNRSAAGGTLLANDPHLKLTAPGTWYLARLELGTGGVIGGTIPG
IPAVLTGRSQQLGWGLTSSYLDDQDLFIEKINPDNPQQYLTPNGYKDFTSRPSIVQIKGNAPLTLTLRWTENGPVLPGSL
FELSTITPPGHVVSLGWTALSREDTSMTAALDLMRAENVAQAIAAGENFIAPSQNITLADHDTIALKTVGVMPDRDLRNQ
SRGRLPNQGWRRENRWQGRLPYAANPEFIAPSGGILGNTNNKLLERPFPNHVSYSWGDTQRINRWRRLMQSREVHTRDSF
IEAQLDTVSYSAQTLLPLIGADLWFTGEAAPNGTPERQRQIALSLLAEWNGEMNEHLPEPLIYASWVRALQKRLIEDDLG
PLADAFDRVEPLFLERVFRNIDGAAAWCDVAQSAPTESCTDMARLALDDALVYISENYGSTLESLRWGDAHQATQDHEVL
GEVPFLRYFVNIRQSTSGGDNTLQRGLTSGEEPAPFNNVHGAGYRGVYDFADPESSVFIIATGQSGHFLSRYYDDMAQYW
RRGEYIPMSLDEKLARAASVGVTRILPRN
>Mature_828_residues
ARLFRWLLRLTAGTILLGILGAILVYFLAAQSLPDYDKEIALPGPTAPVEIVRDNANVPHIFGSFGASDEDVFFGLGYAH
AQDRLWQMAVMRRTAQGRLSEVFGPRTVRTDSFLRRLDLYGAARSSVSAQSPETLRALQAYAAGVNARLQEINEDALGRG
APEMFLFNMPIAPWQPADSIAIMKLMAVQLSSNMQEEILRAQTSIALDDPKRLEDILPDAPGSGTATLPEYTELFPGLPG
FRGLEEQRRAQTAHAALMPLAPRGLGGASNAWAAAPNRSAAGGTLLANDPHLKLTAPGTWYLARLELGTGGVIGGTIPGI
PAVLTGRSQQLGWGLTSSYLDDQDLFIEKINPDNPQQYLTPNGYKDFTSRPSIVQIKGNAPLTLTLRWTENGPVLPGSLF
ELSTITPPGHVVSLGWTALSREDTSMTAALDLMRAENVAQAIAAGENFIAPSQNITLADHDTIALKTVGVMPDRDLRNQS
RGRLPNQGWRRENRWQGRLPYAANPEFIAPSGGILGNTNNKLLERPFPNHVSYSWGDTQRINRWRRLMQSREVHTRDSFI
EAQLDTVSYSAQTLLPLIGADLWFTGEAAPNGTPERQRQIALSLLAEWNGEMNEHLPEPLIYASWVRALQKRLIEDDLGP
LADAFDRVEPLFLERVFRNIDGAAAWCDVAQSAPTESCTDMARLALDDALVYISENYGSTLESLRWGDAHQATQDHEVLG
EVPFLRYFVNIRQSTSGGDNTLQRGLTSGEEPAPFNNVHGAGYRGVYDFADPESSVFIIATGQSGHFLSRYYDDMAQYWR
RGEYIPMSLDEKLARAASVGVTRILPRN

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 91185; Mature: 91054

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLFRWLLRLTAGTILLGILGAILVYFLAAQSLPDYDKEIALPGPTAPVEIVRDNANVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
HIFGSFGASDEDVFFGLGYAHAQDRLWQMAVMRRTAQGRLSEVFGPRTVRTDSFLRRLDL
EEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YGAARSSVSAQSPETLRALQAYAAGVNARLQEINEDALGRGAPEMFLFNMPIAPWQPADS
HHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCHHHHCCCCCCEEEEECCCCCCCCCCH
IAIMKLMAVQLSSNMQEEILRAQTSIALDDPKRLEDILPDAPGSGTATLPEYTELFPGLP
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCC
GFRGLEEQRRAQTAHAALMPLAPRGLGGASNAWAAAPNRSAAGGTLLANDPHLKLTAPGT
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCC
WYLARLELGTGGVIGGTIPGIPAVLTGRSQQLGWGLTSSYLDDQDLFIEKINPDNPQQYL
EEEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHCCCCHHEEEECCCCCCHHCC
TPNGYKDFTSRPSIVQIKGNAPLTLTLRWTENGPVLPGSLFELSTITPPGHVVSLGWTAL
CCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEECCHHH
SREDTSMTAALDLMRAENVAQAIAAGENFIAPSQNITLADHDTIALKTVGVMPDRDLRNQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
SRGRLPNQGWRRENRWQGRLPYAANPEFIAPSGGILGNTNNKLLERPFPNHVSYSWGDTQ
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCCCCHHHCCCCCCCCCCCCCCHH
RINRWRRLMQSREVHTRDSFIEAQLDTVSYSAQTLLPLIGADLWFTGEAAPNGTPERQRQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHH
IALSLLAEWNGEMNEHLPEPLIYASWVRALQKRLIEDDLGPLADAFDRVEPLFLERVFRN
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
IDGAAAWCDVAQSAPTESCTDMARLALDDALVYISENYGSTLESLRWGDAHQATQDHEVL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCCHHCCCCHHHHH
GEVPFLRYFVNIRQSTSGGDNTLQRGLTSGEEPAPFNNVHGAGYRGVYDFADPESSVFII
HCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
ATGQSGHFLSRYYDDMAQYWRRGEYIPMSLDEKLARAASVGVTRILPRN
EECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCCCCC
>Mature Secondary Structure 
ARLFRWLLRLTAGTILLGILGAILVYFLAAQSLPDYDKEIALPGPTAPVEIVRDNANVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCC
HIFGSFGASDEDVFFGLGYAHAQDRLWQMAVMRRTAQGRLSEVFGPRTVRTDSFLRRLDL
EEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YGAARSSVSAQSPETLRALQAYAAGVNARLQEINEDALGRGAPEMFLFNMPIAPWQPADS
HHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCHHHHCCCCCCEEEEECCCCCCCCCCH
IAIMKLMAVQLSSNMQEEILRAQTSIALDDPKRLEDILPDAPGSGTATLPEYTELFPGLP
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCC
GFRGLEEQRRAQTAHAALMPLAPRGLGGASNAWAAAPNRSAAGGTLLANDPHLKLTAPGT
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCC
WYLARLELGTGGVIGGTIPGIPAVLTGRSQQLGWGLTSSYLDDQDLFIEKINPDNPQQYL
EEEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHCCCCHHEEEECCCCCCHHCC
TPNGYKDFTSRPSIVQIKGNAPLTLTLRWTENGPVLPGSLFELSTITPPGHVVSLGWTAL
CCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCEEEECCHHH
SREDTSMTAALDLMRAENVAQAIAAGENFIAPSQNITLADHDTIALKTVGVMPDRDLRNQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
SRGRLPNQGWRRENRWQGRLPYAANPEFIAPSGGILGNTNNKLLERPFPNHVSYSWGDTQ
HCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCCCCHHHCCCCCCCCCCCCCCHH
RINRWRRLMQSREVHTRDSFIEAQLDTVSYSAQTLLPLIGADLWFTGEAAPNGTPERQRQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHH
IALSLLAEWNGEMNEHLPEPLIYASWVRALQKRLIEDDLGPLADAFDRVEPLFLERVFRN
HHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
IDGAAAWCDVAQSAPTESCTDMARLALDDALVYISENYGSTLESLRWGDAHQATQDHEVL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHCCCCHHCCCCHHHHH
GEVPFLRYFVNIRQSTSGGDNTLQRGLTSGEEPAPFNNVHGAGYRGVYDFADPESSVFII
HCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
ATGQSGHFLSRYYDDMAQYWRRGEYIPMSLDEKLARAASVGVTRILPRN
EECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]