Click here to switch to the map view.

The map label for this gene is ctaA

Identifier: 99081176

GI number: 99081176

Start: 1422867

End: 1424012

Strand: Reverse

Name: ctaA

Synonym: TM1040_1335

Alternate gene names: 99081176

Gene position: 1424012-1422867 (Counterclockwise)

Preceding gene: 99081177

Following gene: 99081175

Centisome position: 44.49

GC content: 58.46

Gene sequence:

>1146_bases
ATGAGCAATCGCACGATTTTTGAGGAAGTCTCCTCCGACAGCAAACAACAGTCCTCGCCAACGCCGGGCGGGATTGATCG
CAAGCGCCGGGGCGCGCGCGGTGCGATCCGTGTCTGGCTTGCGGTGCTGTTTGCACTGGTGGTGGCCATGATTGCAGTCG
GCGGCCTGACGCGTCTCACCGACTCTGGTCTTTCGATCACGGAATGGCGTCCCGTGACCGGCGCGGTGCCGCCGATGAGC
GAAGCCGAATGGCAGGCCGAATTCGAGAAATACAAGCAGATCGACCAGTACCATCTGATGAACACATGGATGGAACTCTC
TGACTTTAAAACTATTTACTGGTGGGAATGGGGCCATCGCCAGCTTGGTCGTGTGATCGGATTGATCTGGGCCTTGGGCT
TTTTCGGCTTTCTTGTCACCCGAAGCATCCCAACTGGCTGGACCGGGCGTCTGCTTCTTCCGGGTATTCTCGGCGGTGTT
CAGGGCGCTATCGGTTGGTGGATGGTTGCCTCCGGTGTGACGCTTGGTGAGGGGATGACGTCGGTTGCCTCATACCGGCT
GGCGACACACCTTGGCCTGGCCTTTGTGATCCTCGGTTTCCTGGCCTGGTACATGTTTCTCCTCGGGCGCGAAGAACGCG
ACCTGATGCAGGCGCGGCGCCTGAAGGAAGAAAAGCTCTTTGGCATGAGCACCGGCCTTTTGCACTTTGCCTTCCTGCAG
ATCCTGCTGGGTGCGCTGGTGGCTGGCATTGATGCAGGGCGATCCTACACCGATTGGCCGCTTATGGGGGGGCAGATCTT
TCCACCGCGCCCCTTCATGATTGAGCCTCTGTGGAAAAACTTCTTTGAAAATCCTGGGCTTGTACAGTTCATTCACCGGG
TTGCCGGCTATCTTCTTTTTGCCTTTGCCGTTGTGGTCTGGCTGCGGGGACGCCGGAGCGCACACAAGGCGACGCAATTT
GCCTTCAACGCCGTGTTCGCAGCACTGAGCCTCCAACTCGTGATCGGCATCGTCACAGTCATGACCGCAGCCCCGGTCGA
GATCGCAATCGTTCACCAAGCCGTCGCCGTGCTGGTTTGGGTGCTGATCTTGCGCGCGCGCTTCCTCTCTGCCTATCCTG
TCGCAACTTCCATCAAAGGACATTGA

Upstream 100 bases:

>100_bases
ACAGATGGTCCGTTGGAAGCAGCGCGAAGAGGACTAACTCTCGCTGGACCTTTCCACCCTCAGACCCTAGCGTCCTGCAA
GATTAAGATGTGAGGCCAAG

Downstream 100 bases:

>100_bases
AGACATGAGCTCTTTTGAAGAACTGATTGCTTTTGAACGCCAAACGCAGGCTCTGGGTCAAATCGCAGGTCGGTTGGGCT
GGGATCAGGAGACCATGATG

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSNRTIFEEVSSDSKQQSSPTPGGIDRKRRGARGAIRVWLAVLFALVVAMIAVGGLTRLTDSGLSITEWRPVTGAVPPMS
EAEWQAEFEKYKQIDQYHLMNTWMELSDFKTIYWWEWGHRQLGRVIGLIWALGFFGFLVTRSIPTGWTGRLLLPGILGGV
QGAIGWWMVASGVTLGEGMTSVASYRLATHLGLAFVILGFLAWYMFLLGREERDLMQARRLKEEKLFGMSTGLLHFAFLQ
ILLGALVAGIDAGRSYTDWPLMGGQIFPPRPFMIEPLWKNFFENPGLVQFIHRVAGYLLFAFAVVVWLRGRRSAHKATQF
AFNAVFAALSLQLVIGIVTVMTAAPVEIAIVHQAVAVLVWVLILRARFLSAYPVATSIKGH

Sequences:

>Translated_381_residues
MSNRTIFEEVSSDSKQQSSPTPGGIDRKRRGARGAIRVWLAVLFALVVAMIAVGGLTRLTDSGLSITEWRPVTGAVPPMS
EAEWQAEFEKYKQIDQYHLMNTWMELSDFKTIYWWEWGHRQLGRVIGLIWALGFFGFLVTRSIPTGWTGRLLLPGILGGV
QGAIGWWMVASGVTLGEGMTSVASYRLATHLGLAFVILGFLAWYMFLLGREERDLMQARRLKEEKLFGMSTGLLHFAFLQ
ILLGALVAGIDAGRSYTDWPLMGGQIFPPRPFMIEPLWKNFFENPGLVQFIHRVAGYLLFAFAVVVWLRGRRSAHKATQF
AFNAVFAALSLQLVIGIVTVMTAAPVEIAIVHQAVAVLVWVLILRARFLSAYPVATSIKGH
>Mature_380_residues
SNRTIFEEVSSDSKQQSSPTPGGIDRKRRGARGAIRVWLAVLFALVVAMIAVGGLTRLTDSGLSITEWRPVTGAVPPMSE
AEWQAEFEKYKQIDQYHLMNTWMELSDFKTIYWWEWGHRQLGRVIGLIWALGFFGFLVTRSIPTGWTGRLLLPGILGGVQ
GAIGWWMVASGVTLGEGMTSVASYRLATHLGLAFVILGFLAWYMFLLGREERDLMQARRLKEEKLFGMSTGLLHFAFLQI
LLGALVAGIDAGRSYTDWPLMGGQIFPPRPFMIEPLWKNFFENPGLVQFIHRVAGYLLFAFAVVVWLRGRRSAHKATQFA
FNAVFAALSLQLVIGIVTVMTAAPVEIAIVHQAVAVLVWVLILRARFLSAYPVATSIKGH

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=336, Percent_Identity=34.5238095238095, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI17921987, Length=293, Percent_Identity=35.4948805460751, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17536069, Length=336, Percent_Identity=36.0119047619048, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320989, Length=348, Percent_Identity=35.632183908046, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI19922860, Length=334, Percent_Identity=35.6287425149701, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_SILST (Q1GGZ8)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613330.1
- STRING:   Q1GGZ8
- GeneID:   4075906
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1335
- NMPDR:   fig|292414.1.peg.3556
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q1GGZ8
- ProtClustDB:   CLSK2767268
- BioCyc:   SSP292414:TM1040_1335-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 42488; Mature: 42356

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: BINDING 352-352

Signals:

None

Transmembrane regions:

HASH(0xe7f73e8)-; HASH(0xf85d88c)-; HASH(0xe14c138)-; HASH(0xfd255c8)-; HASH(0xfd45354)-; HASH(0xfd256d0)-; HASH(0xba7d0b0)-; HASH(0xfd25910)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
SNRTIFEEVSSDSKQQSSPTPGGIDRKRRGARGAIRVWLAVLFALVVAMIAVGGLTRLT
CCCHHHHHHCCCCHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHC
DSGLSITEWRPVTGAVPPMSEAEWQAEFEKYKQIDQYHLMNTWMELSDFKTIYWWEWGHR
CCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHH
QLGRVIGLIWALGFFGFLVTRSIPTGWTGRLLLPGILGGVQGAIGWWMVASGVTLGEGMT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
SVASYRLATHLGLAFVILGFLAWYMFLLGREERDLMQARRLKEEKLFGMSTGLLHFAFLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLGALVAGIDAGRSYTDWPLMGGQIFPPRPFMIEPLWKNFFENPGLVQFIHRVAGYLLF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECHHHHHHCCCCCHHHHHHHHHHHHHH
AFAVVVWLRGRRSAHKATQFAFNAVFAALSLQLVIGIVTVMTAAPVEIAIVHQAVAVLVW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VLILRARFLSAYPVATSIKGH
HHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA